Frazier Life Sciences Management, L.P. logo

Frazier Life Sciences Management, L.P. Portfolio Analytics

Investment Analysis & Holdings Breakdown

Comprehensive portfolio analytics for Frazier Life Sciences Management, L.P. with $3.3B in long positions as of Q3 2025, 75% allocated to Healthcare, and 69% concentrated in top 10 positions.

Portfolio Value
$3.3B
Top 10 Concentration
69%
Top Sector
Healthcare (75%)
US Exposure
85%
Market Cap Focus
Mid Cap
Countries
4

Composition Analysis

Portfolio breakdown by sector, industry, and market capitalization

Sector Allocation

Healthcare: 74.70%Healthcare
Healthcare
74.70%

Industry Breakdown

2 industries across all sectors

Biotechnology: 74.21%BiotechnologyDrug Manufacturers - Specialty & Generic: 0.48%
Biotechnology
Healthcare
74.21%
Drug Manufacturers - Specialty & Generic
Healthcare
0.48%

Filter by Sector

Select a sector to filter industries

Market Cap Distribution

Mid Cap ($2B - $10B): 57.73%Mid Cap ($2B - $10B)Small Cap ($300M - $2B): 24.17%Small Cap ($300M - $2B)Micro Cap ($50M - $300M): 1.40%N/A (ETF or Unknown): 16.70%N/A (ETF or Unknown)
Mid Cap ($2B - $10B)
57.73%
Small Cap ($300M - $2B)
24.17%
Micro Cap ($50M - $300M)
1.40%
N/A (ETF or Unknown)
16.70%

Portfolio Concentration

Top 10 Holdings %
69.46%
Top 20 Holdings %
86.32%
Top 50 Holdings %
100.0%
Top 100 Holdings %
100.0%

Geographic Exposure

Portfolio breakdown by country of incorporation

Domestic (US)
84.64%
International
15.36%
Countries
4
Largest Int'l Market
Netherlands - 14.49%
United States of America
84.64% ($2.8B)
43 holdings
Netherlands
14.49% ($483.6M)
2 holdings
Ireland
0.63% ($21.0M)
1 holdings
Canada
0.24% ($7.9M)
1 holdings

Holding Behavior

Investment patterns and position management analysis

Portfolio Stability & Commitment

Avg. Top 10
10.3 quarters
Avg. Top 20
9 quarters
Avg. All Positions
6.5 quarters
Median Holding Period
5 quarters
Persistence Rate
65.96%
Persistent Holdings Weight
85.05%
Persistent Positions
31
Longest Held
Mirum Pharmaceuticals, Inc. Common Stock logo
Mirum Pharmaceuticals, Inc. Common StockMIRM - 14 quarters

Position Sizing & Influence

Current Quarter

Avg. New Position
0.52%
Avg. Position Weight
2.13%
Largest Position
Mirum Pharmaceuticals, Inc. Common Stock logo
Mirum Pharmaceuticals, Inc. Common StockMIRM - 14.93%
Largest Ownership Stake
Phathom Pharmaceuticals, Inc. Common Stock logo
Phathom Pharmaceuticals, Inc. Common StockPHAT - 17.57%
Avg. Ownership Stake
7.70%
Ownership Stake >5%
16
Ownership Stake >1%
29

Historical (Since Q1 2022)

Avg. New Position
2.03%
Avg. Ownership Stake
7.70%
Largest Position
Arcutis Biotherapeutics, Inc. Common Stock logo
Arcutis Biotherapeutics, Inc. Common StockARQT - 22.39% (Q2 2022)
Largest Ownership Stake
HilleVax, Inc. Common Stock logo
HilleVax, Inc. Common StockHLVX - 29.26% (Q4 2022)

Portfolio Turnover

Current Quarter

Turnover Ratio
4.1%
Value Traded
$136.92M
Positions Added
3
Positions Exited
6

Historical (Since Q1 2022)

Avg. Turnover Ratio
12.5%
Avg. Positions Added
8
Avg. Positions Exited
5
Highest Turnover
50.0%
Q1 2022
Lowest Turnover
4.1%
Q3 2025

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