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Ascendis Pharma
ASND • NASDAQ
Ascendis Pharma is a publicly traded company on NASDAQ, led by Jan Moller Mikkelsen. As of Q3 2025, 253 institutional investors hold shares in this company, with total holdings valued at $11.5B. RA CAPITAL MANAGEMENT, LLC is the largest holder with a position valued at $2.0B.
CEOJan Moller Mikkelsen
Employees879.0
Websiteascendispharma.com
Overview
Overview of institutional ownership in ASND as of Q3 2025
All Institutions
- Institutions
- 253
- Value Held
- $11.5B
- Shares Held
- 57.7M
- Avg Position
- $45.4M
- Median Position
- $2.0M
Hedge Funds
- Hedge Funds
- 48
- Value Held
- $2.8B
- Shares Held
- 14.2M
- Avg Position
- $58.9M
- Median Position
- $6.6M
Biggest Investors
Institutions with the largest positions in ASND as of Q3 2025
| Institution | Position Value |
|---|---|
 RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | $2.0B 25.39% of portfolio |
 WESTFIELD CAPITAL MANAGEMENT CO LP Long Only Manager | $1.0B 4.39% of portfolio |
 venBio Select Advisor LLC RIA/Wealth | $1.0B 13.14% of portfolio |
 FMR LLC Institution | $889.0M 0.05% of portfolio |
 HENDERSON GROUP PLC Institution | $859.4M 0.39% of portfolio |
 Artisan Partners Limited Partnership Long Only Manager | $739.7M 1.06% of portfolio |
C Capital International Investors Institution | $608.5M 0.10% of portfolio |
 MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Long Only Manager | $374.3M 0.12% of portfolio |
 WELLINGTON MANAGEMENT CO LLP Long Only Manager | $357.6M 0.06% of portfolio |
 FRANKLIN RESOURCES INC Institution | $316.1M 0.08% of portfolio |
Net Capital Flow
Institutional buying and selling activity for ASND in Q3 2025
- Traded
- +$1.6B
- Buyers
- 152
- Sellers
- 92
- Total Bought
- +$2.1B
- Total Sold
- −$476.4M
- Avg Position
- $41.9M
Biggest Buyers
| Institution | Net Bought |
|---|---|
venBio Select Advisor LLC RIA/Wealth | +$1.0B +130.0K shares |
WELLINGTON MANAGEMENT CO LLP Long Only Manager | +$175.1M +880.8K shares |
 PRINCIPAL FINANCIAL GROUP INC Institution | +$152.2M +765.6K shares |
 Spyglass Capital Management LLC Long Only Manager | +$77.3M +388.6K shares |
 TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | +$35.9M +180.8K shares |
N NEW YORK STATE COMMON RETIREMENT FUND Institution | +$33.8M +-12.7K shares |
F FRED ALGER MANAGEMENT INC Long Only Manager | +$33.2M +166.9K shares |
 ORBIMED ADVISORS LLC Hedge Fund•Sector | +$31.3M +157.5K shares |
 MORGAN STANLEY RIA/Wealth | +$30.2M +152.0K shares |
 PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short | +$24.8M +124.6K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
A ADAGE CAPITAL PARTNERS GP LLC Institution | −$79.3M −459.6K shares |
Artisan Partners Limited Partnership Long Only Manager | −$53.6M −269.5K shares |
 Woodline Partners LP Hedge Fund•Long/Short | −$40.4M −203.0K shares |
WESTFIELD CAPITAL MANAGEMENT CO LP Long Only Manager | −$38.1M −191.5K shares |
FRANKLIN RESOURCES INC Institution | −$32.5M −163.5K shares |
HENDERSON GROUP PLC Institution | −$20.8M −104.7K shares |
 Marshall Wace LLP Institution | −$19.8M −99.5K shares |
S Standard Life Aberdeen plc Institution | −$17.9M −90.2K shares |
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy | −$17.0M −85.3K shares |
 Partner Fund Management, L.P. Hedge Fund•Sector | −$15.2M −76.4K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited ASND in Q3 2025
- New Positions
- 31
- New Value
- $1.2B
- Exited Positions
- 20
- Exited Value
- $99.0M
New Positions
| Institution | Position Value |
|---|---|
venBio Select Advisor LLC RIA/Wealth | $1.0B 5.1M shares |
N NEW YORK STATE COMMON RETIREMENT FUND Institution | $33.8M 169.9K shares |
G GCIC Ltd. Institution | $21.9M 110.0K shares |
 BRAUN STACEY ASSOCIATES INC Private Equity | $18.7M 93.9K shares |
M MOORE CAPITAL MANAGEMENT, LP Hedge Fund•Global Macro | $17.9M 90.0K shares |
 Ally Bridge Group LLC Hedge Fund•Sector | $10.2M 51.1K shares |
 LAZARD ASSET MANAGEMENT LLC Long Only Manager | $8.3M 41.7K shares |
 Jain Global LLC Hedge Fund•Multi-Strategy | $7.1M 36.0K shares |
 Voleon Capital Management LP Hedge Fund•Quant | $6.3M 31.9K shares |
T Troluce Capital Advisors LLC Hedge Fund•Multi-Strategy | $6.0M 30.0K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
A ADAGE CAPITAL PARTNERS GP LLC Institution | $79.3M 459.6K shares |
 Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy | $7.0M 40.4K shares |
S Saturn V Capital Management LLC Hedge Fund•Sector | $6.6M 38.2K shares |
 Verition Fund Management LLC Hedge Fund•Multi-Strategy | $2.6M 15.3K shares |
 Caption Management, LLC Hedge Fund•Long/Short | $1.1M 6.5K shares |
X XTX Topco Ltd Institution | $1.0M 6.1K shares |
 Walleye Trading LLC RIA/Wealth | $449.6K 2.6K shares |
 AIGEN INVESTMENT MANAGEMENT, LP Hedge Fund•Long/Short | $254.6K 1.5K shares |
 R Squared Ltd Private Equity | $209.2K 1.2K shares |
H Headlands Technologies LLC Institution | $206.4K 1.2K shares |
Options Activity
Institutions with the largest Call and Put options positions in ASND as of Q3 2025
- Call Positions
- 13
- Call Value
- $94.3M
- Put Positions
- 10
- Put Value
- $27.7M
Call Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $23.2M 1.2K contracts |
Caption Management, LLC Hedge Fund•Long/Short | $21.0M 1.1K contracts |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $18.6M 938.0 contracts |
J JANE STREET GROUP, LLC Institution | $14.6M 736.0 contracts |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $4.6M 230.0 contracts |
L LMR Partners LLP Institution | $4.2M 210.0 contracts |
Walleye Trading LLC RIA/Wealth | $3.3M 165.0 contracts |
 GOLDMAN SACHS GROUP INC Institution | $1.7M 83.0 contracts |
 Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | $1.5M 75.0 contracts |
D D. E. Shaw & Co., Inc. Institution | $994.1K 50.0 contracts |
Put Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $12.2M 616.0 contracts |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $4.0M 200.0 contracts |
Caption Management, LLC Hedge Fund•Long/Short | $3.0M 149.0 contracts |
J JANE STREET GROUP, LLC Institution | $2.8M 139.0 contracts |
 Lighthouse Investment Partners, LLC Fund of Funds | $2.0M 100.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $1.7M 84.0 contracts |
Walleye Trading LLC RIA/Wealth | $1.6M 80.0 contracts |
C CSS LLC/IL Institution | $397.6K 20.0 contracts |
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy | $59.6K 3.0 contracts |
W WOLVERINE TRADING, LLC Institution | - - contracts |
Most Committed Institutions
Institutions with ASND as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | 25.39% $2.0B |
R Resolute Capital Asset Partners LLC Hedge Fund•Long/Short | 17.38% $32.9M |
venBio Select Advisor LLC RIA/Wealth | 13.14% $1.0B |
Ally Bridge Group LLC Hedge Fund•Sector | 8.50% $10.2M |
T Tri Locum Partners LP Hedge Fund•Long/Short | 7.99% $34.8M |
G GREAT POINT PARTNERS LLC Private Equity | 6.57% $14.9M |
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short | 6.27% $216.4M |
 Catalio Capital Management, LP Venture Capital | 5.33% $28.8M |
N Nan Fung Group Holdings Ltd Institution | 4.54% $2.7M |
WESTFIELD CAPITAL MANAGEMENT CO LP Long Only Manager | 4.39% $1.0B |
Hedge Fund Spotlight
Discover hedge funds investing in ASND
Schonfeld Strategic Advisors LLC
Hedge Fund • Multi-Strategy
Portfolio ManagerRyan Andrew Tolkin
- Portfolio Value
- $14.3B
- Positions
- 1,880
- Last Reported
- Q3 2025
Sector Allocation
A
Position in Ascendis Pharma
- Market Value
- $7.6M
- Shares Held
- 38.3K
- Portfolio Weight
- 0.05%
- Owned Since
- 2022-Q4
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
ETF ETF | $1.3B | 9.09% | |
ETF ETF | $440.9M | 3.08% | |
Unknown Unknown | $337.6M | 2.36% |
