Anavex Life Sciences Corp.
AVXL • NASDAQ
Anavex Life Sciences Corp. is a biotechnology company in the healthcare sector on NASDAQ, led by Christopher Missling, with a market cap of $359.2M. As of Q3 2025, 39% of shares are held by 181 institutional investors, with BlackRock, Inc. as the largest holder at 8.37%.
Chief Executive OfficerChristopher Missling
Market Cap$359.2M
Biotechnology
Healthcare
Employees40.0
Websiteanavex.com
Country
United States of America
Overview
Overview of institutional ownership in AVXL as of Q3 2025 with a market cap of $764.5M
All Institutions
- Institutions
- 181
- Value Held
- $298.7M
- Shares Held
- 32.6M
- Avg Position
- $1.7M
- Median Position
- $181.1K
Hedge Funds
- Hedge Funds
- 12
- Value Held
- $21.4M
- Shares Held
- 2.4M
- Avg Position
- $1.8M
- Median Position
- $433.2K
Ownership Breakdown
Based on market cap of $764.5M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in AVXL as of Q3 2025
| Institution | Position Value |
|---|---|
B BlackRock, Inc. Institution | $64.0M 0.00% of portfolio |
 VANGUARD GROUP INC Institution | $45.4M 0.00% of portfolio |
 STATE STREET CORP Institution | $29.3M 0.00% of portfolio |
 GEODE CAPITAL MANAGEMENT LLC ETF Provider | $18.0M 0.00% of portfolio |
 FRANKLIN RESOURCES INC Institution | $11.0M 0.00% of portfolio |
 TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | $9.2M 0.01% of portfolio |
N NWAM LLC Institution | $8.2M 0.58% of portfolio |
 NORTHERN TRUST CORP Institution | $6.9M 0.00% of portfolio |
 TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy | $6.8M 0.01% of portfolio |
 SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager | $6.4M 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for AVXL in Q3 2025
- Traded
- +$16.6M
- Buyers
- 82
- Sellers
- 65
- Total Bought
- +$29.0M
- Total Sold
- −$12.4M
- Avg Position
- $1.5M
Biggest Buyers
| Institution | Net Bought |
|---|---|
FRANKLIN RESOURCES INC Institution | +$8.9M +302.4K shares |
STATE STREET CORP Institution | +$3.0M +338.3K shares |
 Summit Financial, LLC RIA/Wealth | +$2.0M +221.3K shares |
J JANE STREET GROUP, LLC Institution | +$1.8M +200.5K shares |
B BlackRock, Inc. Institution | +$1.7M +186.5K shares |
 Sheets Smith Investment Management RIA/Wealth | +$1.2M +135.9K shares |
 October Effect Ltd RIA/Wealth | +$1.1M +128.7K shares |
N NATIONAL BANK OF CANADA /FI/ Institution | +$960.2K +107.9K shares |
 WELLINGTON MANAGEMENT CO LLP Long Only Manager | +$835.6K +93.9K shares |
X XTX Topco Ltd Institution | +$727.1K +81.7K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$2.3M −245.6K shares |
 BANK OF AMERICA CORP /DE/ Institution | −$2.2M −243.7K shares |
N NWAM LLC Institution | −$1.4M −150.2K shares |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | −$1.1M −126.5K shares |
 MORGAN STANLEY RIA/Wealth | −$596.8K −67.1K shares |
 UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager | −$584.6K −65.7K shares |
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy | −$577.6K −64.9K shares |
 DIMENSIONAL FUND ADVISORS LP Long Only Manager | −$423.2K −45.9K shares |
 CITIGROUP INC Institution | −$415.0K −46.6K shares |
 Stratos Wealth Partners, LTD. RIA/Wealth | −$245.3K −26.6K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited AVXL in Q3 2025
- New Positions
- 7
- New Value
- $1.3M
- Exited Positions
- 17
- Exited Value
- $3.9M
New Positions
| Institution | Position Value |
|---|---|
Sheets Smith Investment Management RIA/Wealth | $1.2M 135.9K shares |
Q Quarry LP Institution | $36.0K 4.0K shares |
 Sontag Advisory, LLC RIA/Wealth | $13.4K 1.5K shares |
P POM Investment Strategies, LLC Institution | $8.9K 1.0K shares |
R Root Financial Partners, LLC RIA/Wealth | $6.1K 687.0 shares |
 Union Bankshares Corp Institution | $3.1K 350.0 shares |
O Optiver Holding B.V. Institution | $1.8K 204.0 shares |
Exited Positions
| Institution | Previous Position |
|---|---|
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | $2.3M 245.6K shares |
DIMENSIONAL FUND ADVISORS LP Long Only Manager | $423.2K 45.9K shares |
Stratos Wealth Partners, LTD. RIA/Wealth | $245.3K 26.6K shares |
C Corton Capital Inc. Institution | $226.0K 24.5K shares |
 SeaCrest Wealth Management, LLC RIA/Wealth | $181.6K 19.7K shares |
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short | $149.6K 16.2K shares |
A AMERICAN CENTURY COMPANIES INC Institution | $135.2K 14.7K shares |
 Lido Advisors, LLC RIA/Wealth | $111.6K 12.1K shares |
S Squarepoint Ops LLC Hedge Fund•Quant | $99.1K 10.7K shares |
B Berkshire Money Management, Inc. Institution | $92.2K 10.0K shares |
Options Activity
Institutions with the largest Call and Put options positions in AVXL as of Q3 2025
- Call Positions
- 12
- Call Value
- $15.2M
- Put Positions
- 6
- Put Value
- $9.2M
Call Positions
| Institution | Position Value |
|---|---|
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $5.3M 5.9K contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $3.5M 3.9K contracts |
N NOMURA HOLDINGS INC Institution | $1.8M 2.0K contracts |
W WOLVERINE TRADING, LLC Institution | $1.3M 1.5K contracts |
 DIADEMA PARTNERS LP Hedge Fund•Long/Short | $1.2M 1.4K contracts |
J JANE STREET GROUP, LLC Institution | $799.2K 898.0 contracts |
S SIG BROKERAGE, LP Institution | $551.8K 620.0 contracts |
 Caption Management, LLC Hedge Fund•Long/Short | $534.0K 600.0 contracts |
 Watts Gwilliam & Co., LLC RIA/Wealth | $126.1K 1.1K contracts |
$62.3K - contracts |
Put Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $6.2M 7.0K contracts |
 OZ MANAGEMENT LP Hedge Fund•Multi-Strategy | $1.4M 1.6K contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $716.5K 805.0 contracts |
W WOLVERINE TRADING, LLC Institution | $674.7K 780.0 contracts |
N NOMURA HOLDINGS INC Institution | $222.5K 250.0 contracts |
BANK OF AMERICA CORP /DE/ Institution | - - contracts |
Most Committed Institutions
Institutions with AVXL as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
October Effect Ltd RIA/Wealth | 2.41% $2.2M |
Sheets Smith Investment Management RIA/Wealth | 0.78% $1.2M |
 Pier Capital, LLC Long Only Manager | 0.58% $3.7M |
N NWAM LLC Institution | 0.58% $8.2M |
H HEARTLAND ADVISORS INC Long Only Manager | 0.08% $1.6M |
 SAXON INTERESTS, INC. RIA/Wealth | 0.07% $171.8K |
A AXQ CAPITAL, LP Hedge Fund•Market Neutral | 0.06% $170.0K |
H Hikari Power Ltd Institution | 0.06% $761.7K |
Summit Financial, LLC RIA/Wealth | 0.06% $4.0M |
 GSA CAPITAL PARTNERS LLP Hedge Fund•Quant | 0.05% $561.4K |
Hedge Fund Spotlight
Discover hedge funds investing in AVXL
TWO SIGMA ADVISERS, LLC
Hedge Fund • Multi-Strategy
Portfolio ManagerScott David Hoffman
- Portfolio Value
- $50.0B
- Positions
- 2,312
- Last Reported
- Q3 2025
Sector Allocation
Position in Anavex Life Sciences Corp.
- Market Value
- $6.8M
- Shares Held
- 758.5K
- Portfolio Weight
- 0.01%
- Owned Since
- 2022-Q1
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Semiconductors Technology | $1.5B | 3.07% | |
Software - Infrastructure Technology | $1.5B | 3.03% | |
Consumer Electronics Technology | $1.4B | 2.79% |
