AYTU BioPharma, Inc.
AYTU • NASDAQ
AYTU BioPharma, Inc. is a drug manufacturers - specialty & generic company in the healthcare sector on NASDAQ, led by Josh Disbrow, with a market cap of $23.4M. As of Q3 2025, 36% of shares are held by 31 institutional investors, with Nantahala Capital Management, LLC as the largest holder at 10.96%.
Chief Executive OfficerJosh Disbrow
Market Cap$23.4M
Drug Manufacturers - Specialty & Generic
Healthcare
Employees150.0
Websiteaytubio.com
Country
United States of America
Overview
Overview of institutional ownership in AYTU as of Q3 2025 with a market cap of $18.6M
All Institutions
- Institutions
- 31
- Value Held
- $6.7M
- Shares Held
- 3.6M
- Avg Position
- $217.1K
- Median Position
- $6.7K
Hedge Funds
- Hedge Funds
- 6
- Value Held
- $4.1M
- Shares Held
- 2.2M
- Avg Position
- $683.9K
- Median Position
- $345.7K
Ownership Breakdown
Based on market cap of $18.6M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in AYTU as of Q3 2025
| Institution | Position Value |
|---|---|
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy | $2.0M 0.13% of portfolio |
S Stonepine Capital Management, LLC Institution | $1.7M 1.36% of portfolio |
A AWM Investment Company, Inc. Hedge Fund•Event Driven | $1.2M 0.11% of portfolio |
 VANGUARD GROUP INC Institution | $523.7K 0.00% of portfolio |
 DIADEMA PARTNERS LP Hedge Fund•Long/Short | $512.6K 0.36% of portfolio |
 RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | $178.8K 0.00% of portfolio |
 GEODE CAPITAL MANAGEMENT LLC ETF Provider | $133.5K 0.00% of portfolio |
 TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | $129.2K 0.00% of portfolio |
P Persistent Asset Partners Ltd Institution | $117.4K 0.09% of portfolio |
 TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy | $74.8K 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for AYTU in Q3 2025
- Traded
- +$198.0K
- Buyers
- 15
- Sellers
- 6
- Total Bought
- +$1.5M
- Total Sold
- −$1.3M
- Avg Position
- $187.0K
Biggest Buyers
| Institution | Net Bought |
|---|---|
DIADEMA PARTNERS LP Hedge Fund•Long/Short | +$512.6K +272.7K shares |
VANGUARD GROUP INC Institution | +$471.3K +250.7K shares |
S Stonepine Capital Management, LLC Institution | +$148.9K +79.2K shares |
P Persistent Asset Partners Ltd Institution | +$117.4K +62.5K shares |
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy | +$74.8K +39.8K shares |
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | +$63.4K +33.7K shares |
 DIMENSIONAL FUND ADVISORS LP Long Only Manager | +$58.2K +31.0K shares |
GEODE CAPITAL MANAGEMENT LLC ETF Provider | +$32.2K +17.1K shares |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | +$9.8K +5.2K shares |
T Tower Research Capital LLC Institution | +$3.4K +1.8K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 Kanen Wealth Management LLC RIA/Wealth | −$1.2M −573.4K shares |
H HRT FINANCIAL LLC Institution | −$43.6K −20.0K shares |
A AWM Investment Company, Inc. Hedge Fund•Event Driven | −$564.0 −300.0 shares |
S SBI Securities Co., Ltd. Institution | −$281.2 −149.0 shares |
 RAYMOND JAMES FINANCIAL INC RIA/Wealth | −$120.0 −55.0 shares |
N NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO Institution | −$2.0 −1.0 shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited AYTU in Q3 2025
- New Positions
- 2
- New Value
- $630.0K
- Exited Positions
- 4
- Exited Value
- $1.3M
New Positions
| Institution | Position Value |
|---|---|
DIADEMA PARTNERS LP Hedge Fund•Long/Short | $512.6K 272.7K shares |
P Persistent Asset Partners Ltd Institution | $117.4K 62.5K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
Kanen Wealth Management LLC RIA/Wealth | $1.2M 573.4K shares |
H HRT FINANCIAL LLC Institution | $43.6K 20.0K shares |
RAYMOND JAMES FINANCIAL INC RIA/Wealth | $120.0 55.0 shares |
N NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO Institution | $2.0 1.0 shares |
Options Activity
Institutions with the largest Call and Put options positions in AYTU as of Q3 2025
- Call Positions
- 0
- Call Value
- -
- Put Positions
- 0
- Put Value
- -
Call Positions
| Institution | Position Value |
|---|---|
| No call positions found | |
Put Positions
| Institution | Position Value |
|---|---|
| No put positions found | |
Most Committed Institutions
Institutions with AYTU as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
S Stonepine Capital Management, LLC Institution | 1.36% $1.7M |
DIADEMA PARTNERS LP Hedge Fund•Long/Short | 0.36% $512.6K |
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy | 0.13% $2.0M |
A AWM Investment Company, Inc. Hedge Fund•Event Driven | 0.11% $1.2M |
P Persistent Asset Partners Ltd Institution | 0.09% $117.4K |
 Jaffetilchin Investment Partners, LLC RIA/Wealth | 0.00% $32.8K |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | 0.00% $178.8K |
T Tower Research Capital LLC Institution | 0.00% $8.1K |
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | 0.00% $129.2K |
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy | 0.00% $74.8K |
Hedge Fund Spotlight
Discover hedge funds investing in AYTU
N
Nantahala Capital Management, LLC
Hedge Fund • Multi-Strategy
Portfolio ManagerDaniel J. Mack
- Portfolio Value
- $1.6B
- Positions
- 129
- Last Reported
- Q3 2025
Sector Allocation
Position in AYTU BioPharma, Inc.
- Market Value
- $2.0M
- Shares Held
- 1.1M
- Portfolio Weight
- 0.13%
- Owned Since
- 2023-Q1
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Medical - Devices Healthcare | $80.9M | 5.01% | |
Gambling, Resorts & Casinos Consumer Cyclical | $69.7M | 4.32% | |
Banks - Regional Financial Services | $63.8M | 3.95% |
