Cabaletta Bio, Inc.

CABA • NASDAQ

Cabaletta Bio, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Shawn Tomasello, with a market cap of $227.2M. As of Q3 2025, 76% of shares are held by 75 institutional investors, with Bain Capital Life Sciences Investors, LLC as the largest holder at 10.58%.

CEOShawn Tomasello

Market Cap$227.2M

Biotechnology

Healthcare

Employees120.0

Websitecabalettabio.com

Country

United States of America

Overview

Overview of institutional ownership in CABA as of Q3 2025 with a market cap of $214.0M

All Institutions

Institutions: 75
Value Held: $162.0M
Shares Held: 69.2M
Avg Position: $2.2M
Median Position: $223.9K

Hedge Funds

Hedge Funds: 14
Value Held: $37.6M
Shares Held: 16.1M
Avg Position: $2.7M
Median Position: $1.8M

Ownership Breakdown

Institutional (non-HF)

58.08%

$124.3M

Hedge Funds

17.59%

$37.6M

Retail & Other

24.33%

$52.1M

Based on market cap of $214.0M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in CABA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B Bain Capital Life Sciences Investors, LLC Institution	-	$22.6M 1.50% of portfolio	10.58% 9.7M shares	Q2 2023 Held for 2y 5m	$1.5B
A ADAGE CAPITAL PARTNERS GP LLC Institution	-	$20.7M 0.03% of portfolio	9.65% 8.8M shares	Q4 2019 Held for 5y 11m	$63.0B
JENNISON ASSOCIATES LLC Long Only Manager	Jeffrey Todd Becker CEO	$19.9M 0.01% of portfolio	9.29% 8.5M shares	Q1 2023 Held for 2y 8m	$171.73B
T T. Rowe Price Investment Management, Inc. Insurance Manager	John Edward Robison President	$19.6M 0.01% of portfolio	9.14% 8.4M shares	Q4 2023 Held for 1y 11m	$161.58B
C Cormorant Asset Management, LLC Hedge Fund•Long/Short	Bihua Chen CEO	$11.7M 0.91% of portfolio	5.47% 5.0M shares	Q2 2025 Held for 5 months	$1.3B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$9.8M 0.00% of portfolio	4.58% 4.2M shares	Q4 2019 Held for 5y 11m	$6.69T
Woodline Partners LP Hedge Fund•Long/Short	Karl Heinz Kroeker CIO	$5.0M 0.02% of portfolio	2.33% 2.1M shares	Q2 2025 Held for 5 months	$21.3B
H HEIGHTS CAPITAL MANAGEMENT, INC Institution	-	$4.9M 1.73% of portfolio	2.28% 2.1M shares	Q2 2025 Held for 5 months	$282.2M
B BlackRock, Inc. Institution	-	$3.8M 0.00% of portfolio	1.77% 1.6M shares	Q4 2019 Held for 5y 11m	$5.67T
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short	Guo Ting Managing Partner	$3.6M 3.56% of portfolio	1.69% 1.5M shares	Q1 2024 Held for 1y 8m	$101.5M

Net Capital Flow

Institutional buying and selling activity for CABA in Q3 2025

Traded: +$466.4K
Buyers: 40
Sellers: 48
Total Bought: +$29.4M
Total Sold: −$28.9M
Avg Position: $1.7M

Biggest Buyers

Institution	Net Bought	Current Position
JENNISON ASSOCIATES LLC Long Only Manager	+$5.8M +2.5M shares	$19.9M 8.5M shares
T T. Rowe Price Investment Management, Inc. Insurance Manager	+$3.7M +1.6M shares	$19.6M 8.4M shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	+$2.8M +1.2M shares	$3.1M 1.3M shares
Marshall Wace LLP Institution	+$2.7M +1.1M shares	$3.1M 1.3M shares
Woodline Partners LP Hedge Fund•Long/Short	+$2.1M +916.9K shares	$5.0M 2.1M shares
O Opaleye Management Inc. Hedge Fund•Long/Short	+$1.9M +808.9K shares	$1.9M 808.9K shares
VANGUARD GROUP INC Institution	+$1.7M +740.0K shares	$9.8M 4.2M shares
B BlackRock, Inc. Institution	+$1.5M +650.3K shares	$3.8M 1.6M shares
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short	+$1.1M +483.8K shares	$3.6M 1.5M shares
JPMORGAN CHASE & CO Institution	+$1.1M +456.9K shares	$1.3M 537.6K shares

Biggest Sellers

Institution	Net Sold	Current Position
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy	−$8.2M −3.5M shares	$3.0M 1.3M shares
Burkehill Global Management, LP Hedge Fund•Event Driven	−$2.8M −1.2M shares	$1.6M 700.0K shares
Frigate Ventures LP RIA/Wealth	−$2.8M −1.8M shares	Sold Off 0 shares
H HEIGHTS CAPITAL MANAGEMENT, INC Institution	−$2.5M −1.1M shares	$4.9M 2.1M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$2.3M −982.5K shares	$1.7M 705.5K shares
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	−$2.1M −892.1K shares	$3.0M 1.3M shares
B Blue Owl Capital Holdings LP Institution	−$1.7M −1.1M shares	Sold Off 0 shares
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy	−$1.0M −440.7K shares	$2.4M 1.0M shares
C CANTOR FITZGERALD, L. P. Institution	−$809.4K −532.5K shares	Sold Off 0 shares
FEDERATED INVESTORS INC /PA/ Long Only Manager	−$544.1K −232.5K shares	$262.1K 112.0K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited CABA in Q3 2025

New Positions: 6
New Value: $2.1M
Exited Positions: 22
Exited Value: $6.9M

New Positions

Institution	Position Value
O Opaleye Management Inc. Hedge Fund•Long/Short	$1.9M 808.9K shares
Q Quadrature Capital Ltd Institution	$100.4K 42.9K shares
Susquehanna Portfolio Strategies, LLC Private Equity	$79.4K 33.9K shares
B BRYN MAWR TRUST CO/PA Institution	$1.1K 450.0 shares
O Optiver Holding B.V. Institution	$56.0 24.0 shares
SRS Capital Advisors, Inc. RIA/Wealth	$23.0 10.0 shares

Exited Positions

Institution	Previous Position
Frigate Ventures LP RIA/Wealth	$2.8M 1.8M shares
B Blue Owl Capital Holdings LP Institution	$1.7M 1.1M shares
C CANTOR FITZGERALD, L. P. Institution	$809.4K 532.5K shares
PRUDENTIAL FINANCIAL INC Institution	$431.7K 284.0K shares
A AXA Institution	$411.2K 270.5K shares
H HRT FINANCIAL LLC Institution	$189.1K 124.4K shares
THRIVENT FINANCIAL FOR LUTHERANS Insurance Manager	$144.9K 95.3K shares
TCG Crossover Management, LLC Venture Capital	$131.9K 86.8K shares
Jain Global LLC Hedge Fund•Multi-Strategy	$85.4K 56.2K shares
M MYDA Advisors LLC Hedge Fund•Long/Short	$60.8K 40.0K shares

Options Activity

Institutions with the largest Call and Put options positions in CABA as of Q3 2025

Call Positions: 4
Call Value: $2.6M
Put Positions: 2
Put Value: $34.9K

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$976.0K 4.2K contracts
Caption Management, LLC Hedge Fund•Long/Short	$585.0K 2.5K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$572.8K 2.4K contracts
J JANE STREET GROUP, LLC Institution	$445.1K 1.9K contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$34.9K 149.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	- - contracts

Most Committed Institutions

Institutions with CABA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short	Guo Ting Managing Partner	3.56% $3.6M	1.69% 1.5M shares	Q1 2024 Held for 1y 8m	$101.5M
H HEIGHTS CAPITAL MANAGEMENT, INC Institution	-	1.73% $4.9M	2.28% 2.1M shares	Q2 2025 Held for 5 months	$282.2M
B Bain Capital Life Sciences Investors, LLC Institution	-	1.50% $22.6M	10.58% 9.7M shares	Q2 2023 Held for 2y 5m	$1.5B
C Cormorant Asset Management, LLC Hedge Fund•Long/Short	Bihua Chen CEO	0.91% $11.7M	5.47% 5.0M shares	Q2 2025 Held for 5 months	$1.3B
O Opaleye Management Inc. Hedge Fund•Long/Short	James Aaron Silverman President	0.27% $1.9M	0.88% 808.9K shares	Q3 2025 Held for 2 months	$702.7M
Almitas Capital LLC RIA/Wealth	Ronald Dean Mass Managing Partner	0.21% $906.7K	0.42% 387.5K shares	Q1 2025 Held for 8 months	$435.9M
Burkehill Global Management, LP Hedge Fund•Event Driven	Christopher Daniel Rich Managing Partner	0.09% $1.6M	0.77% 700.0K shares	Q2 2025 Held for 5 months	$1.7B
X XTX Topco Ltd Institution	-	0.03% $665.3K	0.31% 284.3K shares	Q2 2025 Held for 5 months	$1.9B
A ADAGE CAPITAL PARTNERS GP LLC Institution	-	0.03% $20.7M	9.65% 8.8M shares	Q4 2019 Held for 5y 11m	$63.0B
R Rangeley Capital, LLC Hedge Fund•Event Driven	Christopher Clay Demuth Jr. Managing Partner	0.03% $26.4K	0.01% 11.3K shares	Q2 2025 Held for 5 months	$105.5M

Hedge Fund Spotlight

Discover hedge funds investing in CABA

Cormorant Asset Management, LLC

Hedge Fund • Long/Short

Portfolio ManagerBihua Chen

Portfolio Value: $1.3B
Positions: 35
Last Reported: Q3 2025

Sector Allocation

Position in Cabaletta Bio, Inc.

Market Value: $11.7M
Shares Held: 5.0M
Portfolio Weight: 0.91%
Owned Since: 2025-Q2

Top Holding	Sector	Market Value	Weight
1 BBOT BridgeBio Oncology Therapeutics, Inc. Common Stock BBOT	Unknown Unknown	$207.0M	16.13%
2 EyePoint, Inc. EYPT	Biotechnology Healthcare	$118.5M	9.23%
3 Rapport Therapeutics, Inc. RAPP	Unknown Unknown	$94.8M	7.39%

View full profile

Cabaletta Bio, Inc.

Overview

All Institutions

Hedge Funds

Ownership Breakdown

Biggest Investors

Net Capital Flow

Biggest Buyers

Biggest Sellers

Entry and Exit Activity

New Positions

Exited Positions

Options Activity

Call Positions

Put Positions

Most Committed Institutions

Hedge Fund Spotlight

Position in Cabaletta Bio, Inc.

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