Monte Rosa Therapeutics, Inc.

GLUE • NASDAQ

Monte Rosa Therapeutics, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Jennifer Champoux, with a market cap of $1.1B. As of Q3 2025, 97% of shares are held by 126 institutional investors, with NEA Management Company, LLC as the largest holder at 12.46%.

Chief Executive OfficerJennifer Champoux

Market Cap$1.1B

Biotechnology

Healthcare

Employees109.0

Websitemonterosatx.com

Country

United States of America

Overview

Overview of institutional ownership in GLUE as of Q3 2025 with a market cap of $457.6M

All Institutions

Institutions: 126
Value Held: $444.8M
Shares Held: 60.0M
Avg Position: $3.5M
Median Position: $257.1K

Hedge Funds

Hedge Funds: 22
Value Held: $95.1M
Shares Held: 12.8M
Avg Position: $4.3M
Median Position: $913.1K

Ownership Breakdown

Institutional (non-HF)

76.42%

$349.7M

Hedge Funds

20.77%

$95.1M

Retail & Other

2.8%

$12.8M

Based on market cap of $457.6M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in GLUE as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
NEA Management Company, LLC Venture Capital	Anthony Angelo Florence CEO	$57.0M 3.13% of portfolio	12.46% 7.7M shares	Q2 2021 Held for 4y 5m	$1.8B
B BVF INC/IL Institution	-	$41.9M 1.70% of portfolio	9.16% 5.7M shares	Q4 2024 Held for 11 months	$2.5B
V Versant Venture Management, LLC Institution	-	$41.9M 19.72% of portfolio	9.15% 5.7M shares	Q4 2024 Held for 11 months	$212.5M
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	$36.4M 0.34% of portfolio	7.96% 4.9M shares	Q1 2023 Held for 2y 8m	$10.8B
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	Robert W Sharps President	$34.4M 0.00% of portfolio	7.51% 4.6M shares	Q2 2021 Held for 4y 5m	$912.31B
B BlackRock, Inc. Institution	-	$28.3M 0.00% of portfolio	6.18% 3.8M shares	Q2 2021 Held for 4y 5m	$5.67T
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	$24.9M 0.75% of portfolio	5.44% 3.4M shares	Q2 2024 Held for 1y 5m	$3.3B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$22.1M 0.00% of portfolio	4.84% 3.0M shares	Q2 2021 Held for 4y 5m	$6.69T
FMR LLC Institution	-	$20.8M 0.00% of portfolio	4.55% 2.8M shares	Q2 2021 Held for 4y 5m	$1.92T
A Aisling Capital Management LP Private Equity	Steven Arnote Elms President	$10.9M 2.39% of portfolio	2.38% 1.5M shares	Q2 2021 Held for 4y 5m	$456.4M

Net Capital Flow

Institutional buying and selling activity for GLUE in Q3 2025

Net Flow: −$28.7M
Buyers: 36
Sellers: 55
Total Bought: +$16.9M
Total Sold: −$45.6M
Avg Position: $3.6M

Biggest Buyers

Institution	Net Bought	Current Position
FMR LLC Institution	+$3.9M +524.2K shares	$20.8M 2.8M shares
Marshall Wace LLP Institution	+$3.4M +456.8K shares	$6.7M 902.8K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$2.8M +380.3K shares	$3.3M 444.9K shares
A AMERICAN CENTURY COMPANIES INC Institution	+$1.4M +190.3K shares	$4.4M 593.4K shares
DIMENSIONAL FUND ADVISORS LP Long Only Manager	+$1.4M +184.0K shares	$4.7M 632.2K shares
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	+$1.2M +157.4K shares	$1.5M 203.6K shares
B BRIDGEWAY CAPITAL MANAGEMENT INC Long Only Manager	+$648.0K +87.5K shares	$2.7M 358.9K shares
MORGAN STANLEY RIA/Wealth	+$553.9K +74.7K shares	$4.8M 645.2K shares
S SIMPLEX TRADING, LLC Institution	+$245.4K +33.1K shares	$245.4K 33.1K shares
Invesco Ltd. ETF Provider	+$240.9K +32.5K shares	$725.4K 97.9K shares

Biggest Sellers

Institution	Net Sold	Current Position
venBio Select Advisor LLC RIA/Wealth	−$16.8M −3.7M shares	Sold Off 0 shares
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	−$12.5M −1.7M shares	$34.4M 4.6M shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$4.2M −566.7K shares	$5.3M 717.3K shares
GOLDMAN SACHS GROUP INC Institution	−$1.8M −247.1K shares	$749.5K 101.1K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	−$1.6M −219.4K shares	$2.9M 395.7K shares
VANGUARD GROUP INC Institution	−$1.1M −151.6K shares	$22.1M 3.0M shares
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	−$1.1M −150.4K shares	$988.9K 133.5K shares
S Squarepoint Ops LLC Hedge Fund•Quant	−$618.2K −83.4K shares	$701.8K 94.7K shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	−$581.4K −78.5K shares	$1.2M 161.5K shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	−$492.6K −109.2K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited GLUE in Q3 2025

New Positions: 16
New Value: $6.7M
Exited Positions: 14
Exited Value: $18.2M

New Positions

Institution	Position Value
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	$1.6M 215.8K shares
M MACQUARIE GROUP LTD Institution	$1.5M 200.0K shares
J JBF Capital, Inc. Institution	$1.1M 148.6K shares
R Rangeley Capital, LLC Hedge Fund•Event Driven	$837.3K 113.0K shares
Empowered Funds, LLC ETF Provider	$648.0K 87.5K shares
C Campbell & CO Investment Adviser LLC Hedge Fund•Quant Macro	$378.9K 51.1K shares
O OMERS ADMINISTRATION Corp Institution	$209.7K 28.3K shares
Scientech Research LLC Hedge Fund•Market Neutral	$120.4K 16.3K shares
V Virtu Financial LLC Institution	$88.6K 12.0K shares
Engineers Gate Manager LP Hedge Fund•Quant	$80.6K 10.9K shares

Exited Positions

Institution	Previous Position
venBio Select Advisor LLC RIA/Wealth	$16.8M 3.7M shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	$492.6K 109.2K shares
Hillsdale Investment Management Inc. Long Only Manager	$271.1K 60.1K shares
Integrated Quantitative Investments LLC Long Only Manager	$159.7K 35.4K shares
S Stonepine Capital Management, LLC Institution	$135.3K 30.0K shares
UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager	$108.7K 24.1K shares
S SHERBROOKE PARK ADVISERS LLC Hedge Fund•Quant	$98.6K 21.9K shares
ING INVESTMENT MANAGEMENT LLC Insurance Manager	$58.4K 13.0K shares
LAZARD ASSET MANAGEMENT LLC Long Only Manager	$49.0K 10.9K shares
BRIGHTON JONES LLC RIA/Wealth	$47.6K 10.6K shares

Options Activity

Institutions with the largest Call and Put options positions in GLUE as of Q3 2025

Call Positions: 3
Call Value: $1.2M
Put Positions: 3
Put Value: $2.0M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$895.9K 1.2K contracts
J JANE STREET GROUP, LLC Institution	$206.0K 278.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$74.8K 101.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$1.3M 1.7K contracts
J JANE STREET GROUP, LLC Institution	$510.5K 689.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$211.2K 285.0 contracts

Most Committed Institutions

Institutions with GLUE as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
V Versant Venture Management, LLC Institution	-	19.72% $41.9M	9.15% 5.7M shares	Q4 2024 Held for 11 months	$212.5M
NEA Management Company, LLC Venture Capital	Anthony Angelo Florence CEO	3.13% $57.0M	12.46% 7.7M shares	Q2 2021 Held for 4y 5m	$1.8B
A Aisling Capital Management LP Private Equity	Steven Arnote Elms President	2.39% $10.9M	2.38% 1.5M shares	Q2 2021 Held for 4y 5m	$456.4M
B BVF INC/IL Institution	-	1.70% $41.9M	9.16% 5.7M shares	Q4 2024 Held for 11 months	$2.5B
R Rangeley Capital, LLC Hedge Fund•Event Driven	Christopher Clay Demuth Jr. Managing Partner	0.79% $837.3K	0.18% 113.0K shares	Q3 2025 Held for 2 months	$105.5M
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	0.75% $24.9M	5.44% 3.4M shares	Q2 2024 Held for 1y 5m	$3.3B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	0.75% $5.1M	1.13% 694.9K shares	Q3 2025 Held for 2 months	$689.7M
P Parkwood LLC Institution	-	0.53% $5.2M	1.15% 708.0K shares	Q3 2024 Held for 1y 2m	$984.9M
Alphabet Inc. Institution	Sundar Pichai CEO	0.45% $10.8M	2.37% 1.5M shares	Q2 2021 Held for 4y 5m	$2.4B
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	0.34% $36.4M	7.96% 4.9M shares	Q1 2023 Held for 2y 8m	$10.8B

Hedge Fund Spotlight

Discover hedge funds investing in GLUE

BAKER BROS. ADVISORS LP

Hedge Fund • Sector

Portfolio ManagerScott Lawrence Lessing

Portfolio Value: $10.8B
Positions: 88
Last Reported: Q3 2025

Sector Allocation

Position in Monte Rosa Therapeutics, Inc.

Market Value: $36.4M
Shares Held: 4.9M
Portfolio Weight: 0.34%
Owned Since: 2023-Q1

Top Holding	Sector	Market Value	Weight
1 Incyte INCY	Biotechnology Healthcare	$2.6B	24.14%
2 Madrigal Pharmaceuticals, Inc. MDGL	Biotechnology Healthcare	$982.3M	9.10%
3 Insmed INSM	Biotechnology Healthcare	$965.4M	8.94%