Ironwood Pharmaceuticals

IRWD • NASDAQ

Ironwood Pharmaceuticals is a drug manufacturers - specialty & generic company in the healthcare sector on NASDAQ, led by Thomas McCourt, with a market cap of $582.4M. As of Q3 2025, 92% of shares are held by 163 institutional investors, with ARMISTICE CAPITAL, LLC as the largest holder at 9.94%.

Interim Chief Executive OfficerThomas McCourt

Market Cap$582.4M

Drug Manufacturers - Specialty & Generic

Healthcare

Employees267.0

Websiteironwoodpharma.com

Country

United States of America

Overview

Overview of institutional ownership in IRWD as of Q3 2025 with a market cap of $212.8M

All Institutions

Institutions: 163
Value Held: $195.2M
Shares Held: 148.9M
Avg Position: $1.2M
Median Position: $65.4K

Hedge Funds

Hedge Funds: 20
Value Held: $80.3M
Shares Held: 61.3M
Avg Position: $4.0M
Median Position: $554.6K

Ownership Breakdown

Institutional (non-HF)

54.0%

$114.9M

Hedge Funds

37.75%

$80.3M

Retail & Other

8.25%

$17.6M

Based on market cap of $212.8M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in IRWD as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
ARMISTICE CAPITAL, LLC Hedge Fund•Long/Short	Steven Joseph Boyd Managing Partner	$21.2M 0.67% of portfolio	9.94% 16.2M shares	Q3 2023 Held for 2y 2m	$3.2B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$21.1M 0.00% of portfolio	9.89% 16.1M shares	≤ Q2 2013 Held for 12y 5m+	$6.69T
Sarissa Capital Management LP Hedge Fund•Activist	Alexander John Denner CEO	$20.9M 11.56% of portfolio	9.80% 15.9M shares	Q4 2017 Held for 7y 11m	$180.4M
B BlackRock, Inc. Institution	-	$15.8M 0.00% of portfolio	7.43% 12.1M shares	≤ Q2 2013 Held for 12y 5m+	$5.67T
BANK OF AMERICA CORP /DE/ Institution	Brian T. Moynihan CEO	$15.3M 0.00% of portfolio	7.20% 11.7M shares	≤ Q2 2013 Held for 12y 5m+	$1.33T
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	$10.9M 0.01% of portfolio	5.14% 8.4M shares	Q1 2019 Held for 6y 8m	$75.8B
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	Gillian Morna Therese Savage CEO	$8.5M 0.02% of portfolio	4.00% 6.5M shares	Q3 2024 Held for 1y 2m	$51.5B
K Kynam Capital Management, LP Hedge Fund•Long/Short	Jared Joseph Keller COO	$7.2M 0.53% of portfolio	3.37% 5.5M shares	Q1 2024 Held for 1y 8m	$1.3B
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	David Gary Kabiller Founder	$7.0M 0.00% of portfolio	3.31% 5.4M shares	Q1 2019 Held for 6y 8m	$156.17B
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	Omar Aguilar Chavez CEO	$6.4M 0.00% of portfolio	3.03% 4.9M shares	≤ Q2 2013 Held for 12y 5m+	$620.51B

Net Capital Flow

Institutional buying and selling activity for IRWD in Q3 2025

Traded: +$6.6M
Buyers: 81
Sellers: 67
Total Bought: +$18.7M
Total Sold: −$12.1M
Avg Position: $1.1M

Biggest Buyers

Institution	Net Bought	Current Position
BANK OF AMERICA CORP /DE/ Institution	+$10.9M +8.3M shares	$15.3M 11.7M shares
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	+$1.6M +1.3M shares	$6.4M 4.9M shares
J JANE STREET GROUP, LLC Institution	+$754.5K +576.0K shares	$3.0M 2.3M shares
H HIGHBRIDGE CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$703.8K +537.3K shares	$703.8K 537.3K shares
UBS Group AG Institution	+$670.1K +511.6K shares	$1.1M 811.7K shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	+$583.6K +445.5K shares	$2.5M 1.9M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$438.6K +334.8K shares	$843.7K 644.0K shares
IEQ CAPITAL, LLC RIA/Wealth	+$222.5K +169.8K shares	$866.8K 661.7K shares
S State of Wyoming Institution	+$205.4K +156.8K shares	$474.8K 362.4K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$201.5K +153.8K shares	$327.7K 250.1K shares

Biggest Sellers

Institution	Net Sold	Current Position
L LSV ASSET MANAGEMENT Long Only Manager	−$2.0M −2.8M shares	Sold Off 0 shares
D D. E. Shaw & Co., Inc. Institution	−$1.7M −1.3M shares	$487.7K 372.3K shares
Marshall Wace LLP Institution	−$1.1M −849.4K shares	$4.1M 3.1M shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$1.0M −787.1K shares	$7.0M 5.4M shares
Q Qube Research & Technologies Ltd Institution	−$712.8K −544.1K shares	$3.7M 2.8M shares
A Amundi Institution	−$558.9K −755.5K shares	Sold Off 0 shares
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	−$538.8K −411.3K shares	$405.5K 309.5K shares
U Universal- Beteiligungs- und Servicegesellschaft mbH Institution	−$526.5K −401.9K shares	$163.6K 124.9K shares
GOLDMAN SACHS GROUP INC Institution	−$472.1K −360.4K shares	$1.4M 1.1M shares
CWM Advisors, LLC ETF Provider	−$396.2K −552.4K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited IRWD in Q3 2025

New Positions: 12
New Value: $263.2K
Exited Positions: 20
Exited Value: $3.8M

New Positions

Institution	Position Value
Krilogy Financial LLC RIA/Wealth	$62.2K 30.2K shares
Requisite Capital Management, LLC RIA/Wealth	$41.6K 31.7K shares
V Vise Technologies, Inc. Institution	$38.8K 29.6K shares
Wedmont Private Capital RIA/Wealth	$17.7K 11.7K shares
waypoint wealth counsel RIA/Wealth	$16.6K 12.7K shares
Cetera Investment Advisers RIA/Wealth	$15.7K 11.9K shares
COLDSTREAM CAPITAL MANAGEMENT INC RIA/Wealth	$14.4K 11.0K shares
Stonebrook Private Inc. RIA/Wealth	$14.4K 11.0K shares
E EVOKE WEALTH, LLC RIA/Wealth	$14.2K 10.8K shares
Kaufman Rossin Wealth, LLC RIA/Wealth	$13.8K 10.5K shares

Exited Positions

Institution	Previous Position
L LSV ASSET MANAGEMENT Long Only Manager	$2.0M 2.8M shares
A Amundi Institution	$558.9K 755.5K shares
CWM Advisors, LLC ETF Provider	$396.2K 552.4K shares
Graham Capital Management, L.P. Hedge Fund•Multi-Strategy	$375.4K 523.4K shares
M Man Group plc Institution	$168.0K 234.3K shares
M MACQUARIE GROUP LTD Institution	$98.1K 136.2K shares
S STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM Institution	$31.8K 44.4K shares
T TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY Institution	$28.5K 39.6K shares
R Squared Ltd Private Equity	$27.8K 38.8K shares
Jain Global LLC Hedge Fund•Multi-Strategy	$20.7K 28.9K shares

Options Activity

Institutions with the largest Call and Put options positions in IRWD as of Q3 2025

Call Positions: 3
Call Value: $14.7M
Put Positions: 1
Put Value: $15.3K

Call Positions

Institution	Position Value
UBS Group AG Institution	$14.7M 112.0K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$35.0K 267.0 contracts
W WOLVERINE TRADING, LLC Institution	$21.9K 154.0 contracts

Put Positions

Institution	Position Value
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$15.3K 117.0 contracts

Most Committed Institutions

Institutions with IRWD as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Sarissa Capital Management LP Hedge Fund•Activist	Alexander John Denner CEO	11.56% $20.9M	9.80% 15.9M shares	Q4 2017 Held for 7y 11m	$180.4M
ARMISTICE CAPITAL, LLC Hedge Fund•Long/Short	Steven Joseph Boyd Managing Partner	0.67% $21.2M	9.94% 16.2M shares	Q3 2023 Held for 2y 2m	$3.2B
K Kynam Capital Management, LP Hedge Fund•Long/Short	Jared Joseph Keller COO	0.53% $7.2M	3.37% 5.5M shares	Q1 2024 Held for 1y 8m	$1.3B
H HIGHBRIDGE CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	Jason Keith Hempel CIO	0.12% $703.8K	0.33% 537.3K shares	Q3 2025 Held for 2 months	$597.8M
S State of Wyoming Institution	-	0.05% $474.8K	0.22% 362.4K shares	Q1 2021 Held for 4y 8m	$879.7M
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	David Khabie-Zeitoune CEO	0.04% $405.5K	0.19% 309.5K shares	Q1 2024 Held for 1y 8m	$1.1B
A Ariadne Wealth Management, LP RIA/Wealth	Gene Lewis Dongieux CCO	0.02% $41.3K	0.01% 12.2K shares	Q2 2025 Held for 5 months	$223.1M
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	Gillian Morna Therese Savage CEO	0.02% $8.5M	4.00% 6.5M shares	Q3 2024 Held for 1y 2m	$51.5B
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	0.01% $10.9M	5.14% 8.4M shares	Q1 2019 Held for 6y 8m	$75.8B
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	Bruce Ira Jacobs President	0.01% $2.5M	1.18% 1.9M shares	Q3 2023 Held for 2y 2m	$25.2B

Hedge Fund Spotlight

Discover hedge funds investing in IRWD

JACOBS LEVY EQUITY MANAGEMENT, INC

Hedge Fund • Quant

Portfolio ManagerBruce Ira Jacobs

Portfolio Value: $25.2B
Positions: 953
Last Reported: Q3 2025

Sector Allocation

Position in Ironwood Pharmaceuticals

Market Value: $2.5M
Shares Held: 1.9M
Portfolio Weight: 0.01%
Owned Since: 2023-Q3

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