LENZ Therapeutics, Inc.

LENZ • NASDAQ

LENZ Therapeutics, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Josh Lehrer, with a market cap of $873.0M. As of Q3 2025, 102% of shares are held by 167 institutional investors, with RA CAPITAL MANAGEMENT, LLC as the largest holder at 14.65%.

Chief Executive OfficerJosh Lehrer

Market Cap$873.0M

Biotechnology

Healthcare

Websitelenz-tx.com

Country

United States of America

Overview

Overview of institutional ownership in LENZ as of Q3 2025 with a market cap of $1.3B

All Institutions

Institutions: 167
Value Held: $1.4B
Shares Held: 29.1M
Avg Position: $8.1M
Median Position: $551.6K

Hedge Funds

Hedge Funds: 26
Value Held: $621.6M
Shares Held: 13.3M
Avg Position: $23.9M
Median Position: $8.7M

Ownership Breakdown

Institutional (non-HF)

55.25%

$734.0M

Hedge Funds

46.78%

$621.6M

Retail & Other

Based on market cap of $1.3B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in LENZ as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	$194.6M 2.42% of portfolio	14.65% 4.2M shares	Q1 2024 Held for 1y 8m	$8.1B
Falcon Edge Capital LP Hedge Fund•Multi-Strategy	Ryan Francis El Khoury Founder	$168.3M 17.04% of portfolio	12.66% 3.6M shares	Q1 2024 Held for 1y 8m	$987.3M
V Versant Venture Management, LLC Institution	-	$123.8M 58.25% of portfolio	9.32% 2.7M shares	Q3 2025 Held for 2 months	$212.5M
B BlackRock, Inc. Institution	-	$68.6M 0.00% of portfolio	5.16% 1.5M shares	Q1 2024 Held for 1y 8m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$62.0M 0.00% of portfolio	4.66% 1.3M shares	Q1 2024 Held for 1y 8m	$6.69T
UBS Group AG Institution	Sergio P. Ermotti CEO	$56.0M 0.01% of portfolio	4.21% 1.2M shares	Q1 2024 Held for 1y 8m	$511.54B
Paradigm Biocapital Advisors LP Hedge Fund•Long/Short	Dr. Senai Nmn Asefaw CIO	$50.0M 1.48% of portfolio	3.76% 1.1M shares	Q4 2024 Held for 11 months	$3.4B
7 72 Investment Holdings, LLC Institution	-	$47.4M 69.77% of portfolio	3.57% 1.0M shares	Q1 2024 Held for 1y 8m	$67.9M
T TANG CAPITAL MANAGEMENT LLC Institution	-	$41.8M 1.65% of portfolio	3.15% 897.6K shares	Q1 2024 Held for 1y 8m	$2.5B
RTW INVESTMENTS, LLC Hedge Fund•Sector	Peter M Fong President	$40.2M 0.50% of portfolio	3.03% 863.4K shares	Q1 2024 Held for 1y 8m	$8.1B

Net Capital Flow

Institutional buying and selling activity for LENZ in Q3 2025

Net Flow: +$32.0M
Buyers: 72
Sellers: 27
Total Bought: +$158.9M
Total Sold: −$126.9M
Avg Position: $9.6M

Biggest Buyers

Institution	Net Bought	Current Position
FRANKLIN RESOURCES INC Institution	+$26.9M +578.5K shares	$27.3M 587.1K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$18.2M +390.4K shares	$18.6M 399.4K shares
UBS Group AG Institution	+$14.9M +320.1K shares	$56.0M 1.2M shares
BANK OF AMERICA CORP /DE/ Institution	+$13.1M +281.2K shares	$16.3M 349.1K shares
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	+$11.0M +236.2K shares	$11.7M 251.1K shares
Rock Springs Capital Management LP Hedge Fund•Sector	+$7.1M +152.2K shares	$11.0M 236.2K shares
N Nuveen, LLC Institution	+$5.0M +107.3K shares	$13.3M 285.5K shares
R Russell Investments Group, Ltd. RIA/Wealth	+$4.7M +100.3K shares	$6.7M 144.5K shares
Invesco Ltd. ETF Provider	+$4.5M +97.6K shares	$17.0M 364.3K shares
S Skandinaviska Enskilda Banken AB Institution	+$4.3M +92.4K shares	$8.6M 185.6K shares

Biggest Sellers

Institution	Net Sold	Current Position
Paradigm Biocapital Advisors LP Hedge Fund•Long/Short	−$30.0M −643.6K shares	$50.0M 1.1M shares
SECTORAL ASSET MANAGEMENT INC Venture Capital	−$28.6M −977.2K shares	Sold Off 0 shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	−$23.1M −495.1K shares	$29.2M 627.6K shares
MORGAN STANLEY RIA/Wealth	−$13.5M −289.1K shares	$13.8M 296.2K shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$13.0M −278.1K shares	$15.8M 340.0K shares
Ally Bridge Group LLC Hedge Fund•Sector	−$7.8M −168.0K shares	$8.2M 175.4K shares
StemPoint Capital LP Hedge Fund•Long/Short	−$5.4M −183.9K shares	Sold Off 0 shares
HARBOR CAPITAL ADVISORS, INC. ETF Provider	−$1.7M −35.4K shares	$680.3K 14.6K shares
A AMERICAN CENTURY COMPANIES INC Institution	−$882.5K −30.1K shares	Sold Off 0 shares
LORD, ABBETT & CO. LLC Long Only Manager	−$797.4K −17.1K shares	$5.3M 114.6K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited LENZ in Q3 2025

New Positions: 46
New Value: $191.9M
Exited Positions: 4
Exited Value: $34.9M

New Positions

Institution	Position Value
V Versant Venture Management, LLC Institution	$123.8M 2.7M shares
First Light Asset Management, LLC Hedge Fund•Sector	$32.3M 693.0K shares
P PLUSTICK MANAGEMENT LLC Hedge Fund•Distressed	$9.3M 200.0K shares
Tyro Capital Management LLC Hedge Fund•Long/Short	$4.7M 100.7K shares
N Neuberger Berman Group LLC Institution	$3.9M 84.0K shares
EAM Investors, LLC Long Only Manager	$3.7M 80.2K shares
N NOMURA ASSET MANAGEMENT CO LTD Long Only Manager	$2.0M 43.8K shares
H HRT FINANCIAL LLC Institution	$1.4M 29.3K shares
C CI Private Wealth, LLC RIA/Wealth	$1.3M 28.3K shares
STATE OF WISCONSIN INVESTMENT BOARD RIA/Wealth	$1.1M 24.1K shares

Exited Positions

Institution	Previous Position
SECTORAL ASSET MANAGEMENT INC Venture Capital	$28.6M 977.2K shares
StemPoint Capital LP Hedge Fund•Long/Short	$5.4M 183.9K shares
A AMERICAN CENTURY COMPANIES INC Institution	$882.5K 30.1K shares
S Stephens Consulting, LLC RIA/Wealth	$30.0 1.0 shares

Options Activity

Institutions with the largest Call and Put options positions in LENZ as of Q3 2025

Call Positions: 4
Call Value: $1.8M
Put Positions: 2
Put Value: $5.8M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$833.8K 179.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$670.8K 144.0 contracts
J JANE STREET GROUP, LLC Institution	$265.5K 57.0 contracts
Caption Management, LLC Hedge Fund•Long/Short	- - contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$4.6M 994.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.2M 249.0 contracts

Most Committed Institutions

Institutions with LENZ as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
7 72 Investment Holdings, LLC Institution	-	69.77% $47.4M	3.57% 1.0M shares	Q1 2024 Held for 1y 8m	$67.9M
V Versant Venture Management, LLC Institution	-	58.25% $123.8M	9.32% 2.7M shares	Q3 2025 Held for 2 months	$212.5M
Falcon Edge Capital LP Hedge Fund•Multi-Strategy	Ryan Francis El Khoury Founder	17.04% $168.3M	12.66% 3.6M shares	Q1 2024 Held for 1y 8m	$987.3M
Ally Bridge Group LLC Hedge Fund•Sector	Slanix Paul T Alex President	6.84% $8.2M	0.61% 175.4K shares	Q2 2025 Held for 5 months	$119.4M
S SCOGGIN LLC Hedge Fund•Event Driven	Todd Matthew Jablonsky CFO	4.19% $10.5M	0.79% 225.0K shares	Q1 2025 Held for 8 months	$250.2M
P PLUSTICK MANAGEMENT LLC Hedge Fund•Distressed	Thomas Johns Hill Managing Partner	3.91% $9.3M	0.70% 200.0K shares	Q3 2025 Held for 2 months	$238.5M
S Saturn V Capital Management LLC Hedge Fund•Sector	Xiaoying (Nmn) Tian Partner	3.76% $17.1M	1.29% 368.2K shares	Q2 2025 Held for 5 months	$456.0M
First Light Asset Management, LLC Hedge Fund•Sector	Mathew Paul Arens CEO	3.04% $32.3M	2.43% 693.0K shares	Q3 2025 Held for 2 months	$1.1B
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	2.42% $194.6M	14.65% 4.2M shares	Q1 2024 Held for 1y 8m	$8.1B
Samsara BioCapital, LLC Venture Capital	Miran Nasruddin Ahmad CFO	2.09% $16.0M	1.20% 343.0K shares	Q1 2024 Held for 1y 8m	$765.9M

Hedge Fund Spotlight

Discover hedge funds investing in LENZ

Falcon Edge Capital LP

Hedge Fund • Multi-Strategy

Portfolio ManagerRyan Francis El Khoury

Portfolio Value: $987.3M
Positions: 27
Last Reported: Q3 2025

Sector Allocation

Position in LENZ Therapeutics, Inc.

Market Value: $168.3M
Shares Held: 3.6M
Portfolio Weight: 17.04%
Owned Since: 2024-Q1

Top Holding	Sector	Market Value	Weight
1 QXO, Inc. QXO	Software - Application Technology	$464.9M	47.08%
2 LENZ Therapeutics, Inc. LENZ	Biotechnology Healthcare	$168.3M	17.04%
3 Metsera, Inc. Common Stock MTSR	Unknown Unknown	$124.8M	12.64%