Monopar Therapeutics

MNPR • NASDAQ

Monopar Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, with a market cap of $498.6M. As of Q3 2025, 70% of shares are held by 55 institutional investors, with HENDERSON GROUP PLC as the largest holder at 20.87%.

Market Cap$498.6M

Biotechnology

Healthcare

Employees12.0

Websitemonopartx.com

Country

United States of America

Overview

Overview of institutional ownership in MNPR as of Q3 2025 with a market cap of $503.9M

All Institutions

Institutions: 55
Value Held: $354.3M
Shares Held: 4.3M
Avg Position: $6.4M
Median Position: $431.9K

Hedge Funds

Hedge Funds: 10
Value Held: $96.9M
Shares Held: 1.2M
Avg Position: $9.7M
Median Position: $5.9M

Ownership Breakdown

Institutional (non-HF)

51.08%

$257.4M

Hedge Funds

19.23%

$96.9M

Retail & Other

29.69%

$149.6M

Based on market cap of $503.9M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in MNPR as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
HENDERSON GROUP PLC Institution	Ali Dibadj CEO	$105.3M 0.05% of portfolio	20.87% 1.3M shares	Q4 2024 Held for 11 months	$218.74B
A ADAGE CAPITAL PARTNERS GP LLC Institution	-	$53.8M 0.09% of portfolio	10.68% 659.2K shares	Q4 2024 Held for 11 months	$63.0B
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	$41.8M 0.52% of portfolio	8.29% 511.2K shares	Q4 2024 Held for 11 months	$8.1B
WELLINGTON MANAGEMENT CO LLP Long Only Manager	Jean Marie Hynes CEO	$18.9M 0.00% of portfolio	3.75% 231.5K shares	Q3 2025 Held for 2 months	$571.21B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$17.0M 0.00% of portfolio	3.37% 208.2K shares	Q1 2021 Held for 4y 8m	$6.69T
B BlackRock, Inc. Institution	-	$16.6M 0.00% of portfolio	3.30% 203.8K shares	Q4 2024 Held for 11 months	$5.67T
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short	James Edward Flynn President	$13.0M 0.22% of portfolio	2.59% 159.8K shares	Q3 2025 Held for 2 months	$6.0B
S Saturn V Capital Management LLC Hedge Fund•Sector	Xiaoying (Nmn) Tian Partner	$12.7M 2.78% of portfolio	2.52% 155.4K shares	Q3 2025 Held for 2 months	$456.0M
TCG Crossover Management, LLC Venture Capital	Chen Ming Yu Managing Partner	$12.5M 0.62% of portfolio	2.48% 153.0K shares	Q3 2025 Held for 2 months	$2.0B
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	Daniel Pawel Schneeberger Managing Partner	$10.6M 1.07% of portfolio	2.11% 130.0K shares	Q4 2024 Held for 11 months	$993.7M

Net Capital Flow

Institutional buying and selling activity for MNPR in Q3 2025

Traded: +$99.8M
Buyers: 33
Sellers: 18
Total Bought: +$107.8M
Total Sold: −$8.0M
Avg Position: $6.0M

Biggest Buyers

Institution	Net Bought	Current Position
WELLINGTON MANAGEMENT CO LLP Long Only Manager	+$18.9M +231.5K shares	$18.9M 231.5K shares
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short	+$13.0M +159.8K shares	$13.0M 159.8K shares
S Saturn V Capital Management LLC Hedge Fund•Sector	+$12.7M +155.4K shares	$12.7M 155.4K shares
TCG Crossover Management, LLC Venture Capital	+$12.5M +153.0K shares	$12.5M 153.0K shares
VANGUARD GROUP INC Institution	+$9.9M +121.7K shares	$17.0M 208.2K shares
HENDERSON GROUP PLC Institution	+$9.4M +115.0K shares	$105.3M 1.3M shares
Vivo Capital, LLC Venture Capital	+$7.4M +90.5K shares	$7.4M 90.5K shares
DRIEHAUS CAPITAL MANAGEMENT LLC Hedge Fund•Event Driven	+$5.3M +64.6K shares	$5.3M 64.6K shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	+$4.9M +60.0K shares	$53.8M 659.2K shares
STATE STREET CORP Institution	+$2.5M +30.4K shares	$5.9M 72.2K shares

Biggest Sellers

Institution	Net Sold	Current Position
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$3.7M −104.0K shares	Sold Off 0 shares
UBS Group AG Institution	−$1.1M −13.9K shares	$651.2K 8.0K shares
GEODE CAPITAL MANAGEMENT LLC ETF Provider	−$976.8K −12.0K shares	$6.9M 85.0K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$608.9K −7.5K shares	$599.0K 7.3K shares
NORTHERN TRUST CORP Institution	−$404.9K −5.0K shares	$2.2M 26.9K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	−$329.0K −4.0K shares	$353.5K 4.3K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$223.0K −6.2K shares	Sold Off 0 shares
N NEW YORK STATE COMMON RETIREMENT FUND Institution	−$138.8K −1.7K shares	$98.0K 1.2K shares
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	−$118.6K −1.5K shares	$963.5K 11.8K shares
B BlackRock, Inc. Institution	−$115.8K −1.4K shares	$16.6M 203.8K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited MNPR in Q3 2025

New Positions: 14
New Value: $72.7M
Exited Positions: 3
Exited Value: $4.0M

New Positions

Institution	Position Value
WELLINGTON MANAGEMENT CO LLP Long Only Manager	$18.9M 231.5K shares
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short	$13.0M 159.8K shares
S Saturn V Capital Management LLC Hedge Fund•Sector	$12.7M 155.4K shares
TCG Crossover Management, LLC Venture Capital	$12.5M 153.0K shares
Vivo Capital, LLC Venture Capital	$7.4M 90.5K shares
DRIEHAUS CAPITAL MANAGEMENT LLC Hedge Fund•Event Driven	$5.3M 64.6K shares
EAM Investors, LLC Long Only Manager	$1.2M 14.6K shares
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy	$997.6K 12.2K shares
N Nuveen, LLC Institution	$344.7K 4.2K shares
S STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM Institution	$286.5K 3.5K shares

Exited Positions

Institution	Previous Position
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	$3.7M 104.0K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$223.0K 6.2K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	$15.4K 431.0 shares

Options Activity

Institutions with the largest Call and Put options positions in MNPR as of Q3 2025

Call Positions: 0
Call Value: -
Put Positions: 0
Put Value: -

Call Positions

Institution	Position Value
No call positions found

Put Positions

Institution	Position Value
No put positions found

Most Committed Institutions

Institutions with MNPR as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Ally Bridge Group LLC Hedge Fund•Sector	Slanix Paul T Alex President	4.41% $5.3M	1.04% 64.5K shares	Q2 2025 Held for 5 months	$119.4M
S Saturn V Capital Management LLC Hedge Fund•Sector	Xiaoying (Nmn) Tian Partner	2.78% $12.7M	2.52% 155.4K shares	Q3 2025 Held for 2 months	$456.0M
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	Daniel Pawel Schneeberger Managing Partner	1.07% $10.6M	2.11% 130.0K shares	Q4 2024 Held for 11 months	$993.7M
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	Jonathan Bo-Shing Chu Founder	0.66% $6.5M	1.29% 79.5K shares	Q1 2025 Held for 8 months	$983.0M
TCG Crossover Management, LLC Venture Capital	Chen Ming Yu Managing Partner	0.62% $12.5M	2.48% 153.0K shares	Q3 2025 Held for 2 months	$2.0B
Vivo Capital, LLC Venture Capital	Jack Bech Nielsen Managing Partner	0.59% $7.4M	1.47% 90.5K shares	Q3 2025 Held for 2 months	$1.2B
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	0.52% $41.8M	8.29% 511.2K shares	Q4 2024 Held for 11 months	$8.1B
GERBER, LLC RIA/Wealth	Randall Thomas Gerber Managing Partner	0.29% $457.4K	0.09% 5.6K shares	Q1 2025 Held for 8 months	$158.9M
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short	James Edward Flynn President	0.22% $13.0M	2.59% 159.8K shares	Q3 2025 Held for 2 months	$6.0B
EAM Investors, LLC Long Only Manager	Derek John Gaertner CEO	0.14% $1.2M	0.24% 14.6K shares	Q3 2025 Held for 2 months	$873.4M