Oric Pharmaceuticals, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Jacob M. Chacko, M.D., with a market cap of $913.5M. As of Q3 2025, 110% of shares are held by 151 institutional investors, with Nextech Invest, Ltd. as the largest holder at 7.37%.
Overview of institutional ownership in ORIC as of Q3 2025 with a market cap of $1.2B
Based on market cap of $1.2B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Institutions with the largest positions in ORIC as of Q3 2025
| Institution | Position Value |
|---|---|
N Nextech Invest, Ltd. Institution | $86.0M 13.08% of portfolio |
EcoR1 Capital, LLC Hedge Fund•Sector | $80.7M 3.87% of portfolio |
VR Adviser, LLC Venture Capital | $79.2M 4.46% of portfolio |
VIKING GLOBAL INVESTORS LP Hedge Fund•Long/Short | $78.9M 0.21% of portfolio |
PFIZER INC Institution | $64.5M 14.75% of portfolio |
B BlackRock, Inc. Institution | $63.3M 0.00% of portfolio |
VANGUARD GROUP INC Institution | $55.8M 0.00% of portfolio |
SR ONE CAPITAL MANAGEMENT, LP Venture Capital | $54.2M 7.84% of portfolio |
A ALKEON CAPITAL MANAGEMENT LLC Hedge Fund•Long/Short | $54.0M 0.25% of portfolio |
NEA Management Company, LLC Venture Capital | $49.4M 2.71% of portfolio |
Institutional buying and selling activity for ORIC in Q3 2025
| Institution | Net Bought |
|---|---|
EcoR1 Capital, LLC Hedge Fund•Sector | +$61.3M +5.1M shares |
ORBIMED ADVISORS LLC Hedge Fund•Sector | +$32.9M +2.7M shares |
VANGUARD GROUP INC Institution | +$18.3M +1.5M shares |
R ROYCE & ASSOCIATES LLC Institution | +$14.7M +1.2M shares |
B BlackRock, Inc. Institution | +$14.4M +1.2M shares |
STATE STREET CORP Institution | +$9.3M +771.8K shares |
GEODE CAPITAL MANAGEMENT LLC ETF Provider | +$6.3M +522.3K shares |
NORTHERN TRUST CORP Institution | +$5.9M +487.6K shares |
Polar Capital Holdings Plc Long Only Manager | +$5.6M +468.6K shares |
GOLDMAN SACHS GROUP INC Institution | +$5.0M +415.2K shares |
| Institution | Net Sold |
|---|---|
Frazier Life Sciences Management, L.P. Venture Capital | −$10.8M −1.1M shares |
Ally Bridge Group LLC Hedge Fund•Sector | −$4.9M −485.6K shares |
Integral Health Asset Management, LLC Hedge Fund•Sector | −$4.2M −350.0K shares |
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$3.1M −258.4K shares |
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short | −$3.1M −255.6K shares |
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | −$2.8M −230.7K shares |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$2.5M −210.1K shares |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | −$2.5M −204.8K shares |
BANK OF AMERICA CORP /DE/ Institution | −$2.3M −195.0K shares |
A Arrowpoint Asset Management, LLC Hedge Fund•Multi-Strategy | −$2.2M −181.0K shares |
Institutions that initiated new positions or completely exited ORIC in Q3 2025
| Institution | Position Value |
|---|---|
Polar Capital Holdings Plc Long Only Manager | $5.6M 468.6K shares |
Exome Asset Management LLC Hedge Fund•Sector | $1.4M 120.6K shares |
Optimize Financial Inc RIA/Wealth | $468.5K 39.0K shares |
D DARK FOREST CAPITAL MANAGEMENT LP Pension/Endowment | $358.2K 29.9K shares |
Susquehanna Portfolio Strategies, LLC Private Equity | $330.3K 27.5K shares |
F FOX RUN MANAGEMENT, L.L.C. Hedge Fund•Quant | $202.6K 16.9K shares |
Jain Global LLC Hedge Fund•Multi-Strategy | $181.8K 15.2K shares |
Quantinno Capital Management LP Hedge Fund•Market Neutral | $147.2K 12.3K shares |
$141.2K 10.0K shares | |
GENWORTH FINANCIAL WEALTH MANAGEMENT, INC Long Only Manager | $37.1K 3.1K shares |
| Institution | Previous Position |
|---|---|
Frazier Life Sciences Management, L.P. Venture Capital | $10.8M 1.1M shares |
Ally Bridge Group LLC Hedge Fund•Sector | $4.9M 485.6K shares |
H HRT FINANCIAL LLC Institution | $1.0M 102.6K shares |
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant | $775.9K 76.4K shares |
F FRED ALGER MANAGEMENT INC Long Only Manager | $774.3K 76.3K shares |
UBS OCONNOR LLC Long Only Manager | $497.4K 49.0K shares |
AMERIPRISE FINANCIAL INC Institution | $394.5K 38.9K shares |
TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy | $340.3K 33.5K shares |
IEQ CAPITAL, LLC RIA/Wealth | $233.3K 23.0K shares |
P Point72 Asia Pte. Ltd. Institution | $212.1K 20.9K shares |
Institutions with the largest Call and Put options positions in ORIC as of Q3 2025
| Institution | Position Value |
|---|---|
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $265.2K 221.0 contracts |
J JANE STREET GROUP, LLC Institution | $156.0K 130.0 contracts |
Caption Management, LLC Hedge Fund•Long/Short | - - contracts |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | - - contracts |
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $1.4M 1.1K contracts |
Caption Management, LLC Hedge Fund•Long/Short | $720.0K 600.0 contracts |
Institutions with ORIC as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
C Column Group LLC Institution | 52.48% $42.5M |
PFIZER INC Institution | 14.75% $64.5M |
N Nextech Invest, Ltd. Institution | 13.08% $86.0M |
SR ONE CAPITAL MANAGEMENT, LP Venture Capital | 7.84% $54.2M |
E Euclidean Capital LLC Institution | 4.99% $11.9M |
VR Adviser, LLC Venture Capital | 4.46% $79.2M |
F First Turn Management, LLC Hedge Fund•Long/Short | 3.89% $25.9M |
EcoR1 Capital, LLC Hedge Fund•Sector | 3.87% $80.7M |
MPM Oncology Impact Management LP Institution | 3.40% $20.8M |
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | 3.39% $23.4M |
Discover hedge funds investing in ORIC

| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
ETF ETF | $1.1B | 2.29% | |
Software - Infrastructure Technology | $1.1B | 2.23% | |
Semiconductors Technology | $905.7M | 1.88% |
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