Spruce Biosciences, Inc.
 logo

Spruce Biosciences, Inc.

SPRB and SPRBDNASDAQ

Spruce Biosciences, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Javier Szwarcberg, with a market cap of $86.3M. As of Q3 2025, 499% of shares are held by 9 institutional investors, with Carlyle Group L.P. as the largest holder at 100.0%.

Chief Executive OfficerJavier Szwarcberg
Market Cap$86.3M
Biotechnology
Healthcare
Employees22.0
Country
United States of America

Overview

Overview of institutional ownership in SPRB and SPRBD as of Q3 2025 with a market cap of $5.0M

All Institutions

Institutions
9
Value Held
$25.1M
Shares Held
2.9M
Avg Position
$2.8M
Median Position
$1.2K

Hedge Funds

Hedge Funds
3
Value Held
$366.9K
Shares Held
41.0K
Avg Position
$122.3K
Median Position
$119.3K

Ownership Breakdown

Institutional (non-HF): 491.51%Institutional (non-HF)Hedge Funds: 7.28%Retail & Other: -
Institutional (non-HF)
491.51%
$24.8M
Hedge Funds
7.28%
$366.9K
Retail & Other
-
-

Based on market cap of $5.0M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in SPRB and SPRBD as of Q3 2025

InstitutionPosition Value
$24.8M
0.58% of portfolio
Cable Car Capital LLC logo
Cable Car Capital LLC
Hedge FundLong/Short
$238.7K
0.20% of portfolio
Ikarian Capital, LLC logo
Ikarian Capital, LLC
Hedge FundEvent Driven
$119.3K
0.02% of portfolio
L
Lion Point Capital, LP
Hedge FundEvent Driven
$9.0K
0.05% of portfolio
UBS Group AG logo
UBS Group AG
Institution
$1.2K
0.00% of portfolio
$931.0
0.00% of portfolio
MORGAN STANLEY logo
MORGAN STANLEY
RIA/Wealth
$878.0
0.00% of portfolio
$116.0
0.00% of portfolio
$27.0
0.00% of portfolio
-
0.00% of portfolio

Net Capital Flow

Institutional buying and selling activity for SPRB and SPRBD in Q3 2025

Traded
+$25.1M
Buyers
9
Sellers
0
Total Bought
+$25.1M
Total Sold
-
Avg Position
$2.5M

Biggest Buyers

InstitutionNet Bought
+$24.8M
+2.9M shares
Cable Car Capital LLC logo
Cable Car Capital LLC
Hedge FundLong/Short
+$238.7K
+26.7K shares
Ikarian Capital, LLC logo
Ikarian Capital, LLC
Hedge FundEvent Driven
+$117.7K
+13.2K shares
L
Lion Point Capital, LP
Hedge FundEvent Driven
+$9.0K
+1.0K shares
UBS Group AG logo
UBS Group AG
Institution
+$1.2K
+132.0 shares
+$931.0
+133.0 shares
MORGAN STANLEY logo
MORGAN STANLEY
RIA/Wealth
+$878.0
+98.0 shares
+$114.4
+12.8 shares
+$27.0
+3.0 shares

Biggest Sellers

InstitutionNet Sold
No sellers found

Entry and Exit Activity

Institutions that initiated new positions or completely exited SPRB and SPRBD in Q3 2025

New Positions
3
New Value
$239.6K
Exited Positions
1
Exited Value
-

New Positions

InstitutionPosition Value
Cable Car Capital LLC logo
Cable Car Capital LLC
Hedge FundLong/Short
$238.7K
26.7K shares
$931.0
133.0 shares
-
- shares

Exited Positions

InstitutionPrevious Position
-
185.9 shares

Options Activity

Institutions with the largest Call and Put options positions in SPRB and SPRBD as of Q3 2025

Call Positions
0
Call Value
-
Put Positions
0
Put Value
-

Call Positions

InstitutionPosition Value
No call positions found

Put Positions

InstitutionPosition Value
No put positions found

Most Committed Institutions

Institutions with SPRB and SPRBD as the highest % of their portfolio as of Q3 2025

InstitutionPortfolio Weight
0.58%
$24.8M
Cable Car Capital LLC logo
Cable Car Capital LLC
Hedge FundLong/Short
0.20%
$238.7K
L
Lion Point Capital, LP
Hedge FundEvent Driven
0.05%
$9.0K
Ikarian Capital, LLC logo
Ikarian Capital, LLC
Hedge FundEvent Driven
0.02%
$119.3K
0.00%
$116.0
0.00%
$931.0
UBS Group AG logo
UBS Group AG
Institution
0.00%
$1.2K
MORGAN STANLEY logo
MORGAN STANLEY
RIA/Wealth
0.00%
$878.0
0.00%
$27.0
0.00%
-

Hedge Fund Spotlight

Discover hedge funds investing in SPRB and SPRBD

Cable Car Capital LLC logo
Cable Car Capital LLC
Hedge FundLong/Short
Portfolio ManagerEvan Howell Eurich
Portfolio Value
$119.3M
Positions
48
Last Reported
Q3 2025
AddressSan Francisco, CA
Sector Allocation
Healthcare: 14.90%HealthcareIndustrials: 9.00%IndustrialsFinancial Services: 2.70%Financial ServicesCommunication Services: 1.90%Real Estate: 1.10%Consumer Defensive: 0.80%Technology: 0.40%ETF: 0.30%
Spruce Biosciences, Inc.
 logo

Position in Spruce Biosciences, Inc.

SPRB and SPRBD

Market Value
$238.7K
Shares Held
26.7K
Portfolio Weight
0.20%
Owned Since
2025-Q3
Top HoldingSectorMarket ValueWeight
Unknown
Unknown
$15.4M12.91%
Unknown
Unknown
$10.9M9.11%
Unknown
Unknown
$9.6M8.06%

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