ORBIMED ADVISORS LLC logo

ORBIMED ADVISORS LLC Portfolio Analytics

Investment Analysis & Holdings Breakdown

Comprehensive portfolio analytics for ORBIMED ADVISORS LLC with $4.1B in long positions as of Q3 2025, 85% allocated to Healthcare, and 42% concentrated in top 10 positions.

Portfolio Value
$4.1B
Top 10 Concentration
42%
Top Sector
Healthcare (85%)
US Exposure
92%
Market Cap Focus
Small Cap
Countries
9

Composition Analysis

Portfolio breakdown by sector, industry, and market capitalization

Sector Allocation

Healthcare: 85.00%Healthcare
Healthcare
85.00%

Industry Breakdown

8 industries across all sectors

Biotechnology: 54.32%BiotechnologyMedical - Devices: 14.59%Medical - DevicesDrug Manufacturers - General: 5.57%Medical - Diagnostics & Research: 4.81%Medical - Instruments & Supplies: 3.12%Drug Manufacturers - Specialty & Generic: 1.20%2 more: 1.33%
Biotechnology
Healthcare
54.32%
Medical - Devices
Healthcare
14.59%
Drug Manufacturers - General
Healthcare
5.57%
Medical - Diagnostics & Research
Healthcare
4.81%
Medical - Instruments & Supplies
Healthcare
3.12%
Drug Manufacturers - Specialty & Generic
Healthcare
1.20%
Medical - Healthcare Plans
Healthcare
1.14%
Medical - Healthcare Information Services
Healthcare
0.19%

Filter by Sector

Select a sector to filter industries

Market Cap Distribution

Mega Cap (> $200B): 5.57%Large Cap ($10B - $200B): 27.97%Large Cap ($10B - $200B)Mid Cap ($2B - $10B): 15.24%Mid Cap ($2B - $10B)Small Cap ($300M - $2B): 35.66%Small Cap ($300M - $2B)Micro Cap ($50M - $300M): 3.87%Nano Cap (< $50M): 2.42%N/A (ETF or Unknown): 9.27%N/A (ETF or Unknown)
Mega Cap (> $200B)
5.57%
Large Cap ($10B - $200B)
27.97%
Mid Cap ($2B - $10B)
15.24%
Small Cap ($300M - $2B)
35.66%
Micro Cap ($50M - $300M)
3.87%
Nano Cap (< $50M)
2.42%
N/A (ETF or Unknown)
9.27%

Portfolio Concentration

Top 10 Holdings %
41.79%
Top 20 Holdings %
61.91%
Top 50 Holdings %
90.77%
Top 100 Holdings %
100.0%

Geographic Exposure

Portfolio breakdown by country of incorporation

Domestic (US)
92.2%
International
7.8%
Countries
9
Largest Int'l Market
China - 4.47%
United States of America
92.20% ($3.8B)
84 holdings
China
4.47% ($184.5M)
1 holdings
United Kingdom
1.00% ($41.1M)
1 holdings
Canada
0.81% ($33.5M)
4 holdings
Netherlands
0.65% ($26.8M)
1 holdings
Switzerland
0.57% ($23.6M)
1 holdings
Germany
0.14% ($5.8M)
2 holdings
Israel
0.12% ($5.1M)
1 holdings
Ireland
0.03% ($1.2M)
1 holdings

Holding Behavior

Investment patterns and position management analysis

Portfolio Stability & Commitment

Avg. Top 10
22.8 quarters
Avg. Top 20
15.6 quarters
Avg. All Positions
10.2 quarters
Median Holding Period
5 quarters
Persistence Rate
58.33%
Persistent Holdings Weight
72.7%
Persistent Positions
56
Longest Held
Sinovac Biotech, Ltd logo
Sinovac Biotech, LtdSVA - 49 quarters

Position Sizing & Influence

Current Quarter

Avg. New Position
0.20%
Avg. Position Weight
1.04%
Largest Position
Edgewise Therapeutics, Inc. Common Stock logo
Edgewise Therapeutics, Inc. Common StockEWTX - 6.11%
Largest Ownership Stake
Prelude Therapeutics Incorporated logo
Prelude Therapeutics IncorporatedPRLD - 19.27%
Avg. Ownership Stake
3.92%
Ownership Stake >5%
30
Ownership Stake >1%
57

Historical (Since Q2 2013)

Avg. New Position
0.69%
Avg. Ownership Stake
4.56%
Largest Position
Aptose Biosciences, Inc. logo
Aptose Biosciences, Inc.APTO - 72.54% (Q1 2021)
Largest Ownership Stake
Xtant Medical Holdings, Inc. logo
Xtant Medical Holdings, Inc.XTNT - 83.96% (Q2 2021)

Portfolio Turnover

Current Quarter

Turnover Ratio
14.3%
Value Traded
$589.80M
Positions Added
7
Positions Exited
15

Historical (Since Q2 2013)

Avg. Turnover Ratio
15.6%
Avg. Positions Added
13
Avg. Positions Exited
15
Highest Turnover
34.3%
Q3 2021
Lowest Turnover
3.6%
Q2 2021

Cookie Preferences

We use cookies for analytics. See our Privacy and Cookie Policy.