ORBIMED ADVISORS LLC
Hedge Fund • Sector
ORBIMED ADVISORS LLC is a Sector-focused Hedge Fund based in New York, NY led by Sam Block Iii, reporting $17.3B in AUM as of Q3 2025 with 85% Healthcare concentration.
CFOSam Block Iii
- Portfolio Value
- $4.1B
- Positions
- 96
- Top Holding
- EWTX at 6.11%
- Last Reported
- Q3 2025
Top Holdings
Largest long holdings in ORBIMED ADVISORS LLC's portfolio (41.8% of total portfolio)
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| Holding | Sector | Position | Weight | Traded | Ownership |
|---|---|---|---|---|---|
Biotechnology Healthcare | $251.7M | 6.11% | — | 14.73% 15.5M shares | |
Medical - Devices Healthcare | $237.2M | 5.75% | -$37.5M Sold | 0.16% 2.4M shares | |
Drug Manufacturers - General Healthcare | $229.8M | 5.57% | -$27.8M Sold | 0.03% 301.2K shares | |
Biotechnology Healthcare | $184.5M | 4.47% | — | — 2.7M shares | |
Biotechnology Healthcare | $162.9M | 3.95% | — | 13.44% 8.0M shares | |
Biotechnology Healthcare | $137.5M | 3.34% | -$18.4M Sold | 0.23% 301.6K shares | |
Medical - Devices Healthcare | $132.8M | 3.22% | — | 0.09% 359.2K shares | |
Medical - Devices Healthcare | $131.0M | 3.18% | -$1.9M Sold | 0.29% 1.7M shares | |
Medical - Instruments & Supplies Healthcare | $128.4M | 3.12% | -$1.7M Sold | 0.08% 287.2K shares | |
Unknown Unknown | $127.1M | 3.08% | -$26.3M Sold | — 172.3K shares |
Changes
Portfolio activity, position movements, and quarter-over-quarter changes in ORBIMED ADVISORS LLC's latest filing
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Market Value
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Net Flows % of MV
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Decreased Positions
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Analytics
Portfolio insights and performance metrics for ORBIMED ADVISORS LLC
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