Sio Capital Management, LLC logo

Sio Capital Management, LLC Portfolio Analytics

Investment Analysis & Holdings Breakdown

Comprehensive portfolio analytics for Sio Capital Management, LLC with $395.2M in long positions as of Q3 2025, 68% allocated to Healthcare, and 60% concentrated in top 10 positions.

Portfolio Value
$395.2M
Top 10 Concentration
60%
Top Sector
Healthcare (68%)
US Exposure
89%
Market Cap Focus
Mid Cap
Countries
6

Composition Analysis

Portfolio breakdown by sector, industry, and market capitalization

Sector Allocation

Healthcare: 68.20%HealthcareIndustrials: 12.90%IndustrialsConsumer Defensive: 3.50%
Healthcare
68.20%
Industrials
12.90%
Consumer Defensive
3.50%

Industry Breakdown

10 industries across all sectors

Biotechnology: 46.34%BiotechnologySpecialty Business Services: 12.89%Specialty Business ServicesMedical - Instruments & Supplies: 5.10%Drug Manufacturers - General: 3.77%Medical - Distribution: 3.68%Medical - Healthcare Plans: 3.50%Household & Personal Products: 3.47%Drug Manufacturers - Specialty & Generic: 3.41%2 more: 2.39%
Biotechnology
Healthcare
46.34%
Specialty Business Services
Industrials
12.89%
Medical - Instruments & Supplies
Healthcare
5.10%
Drug Manufacturers - General
Healthcare
3.77%
Medical - Distribution
Healthcare
3.68%
Medical - Healthcare Plans
Healthcare
3.50%
Household & Personal Products
Consumer Defensive
3.47%
Drug Manufacturers - Specialty & Generic
Healthcare
3.41%
Medical - Healthcare Information Services
Healthcare
1.22%
Medical - Devices
Healthcare
1.17%

Filter by Sector

Select a sector to filter industries

Market Cap Distribution

Mega Cap (> $200B): 3.77%Large Cap ($10B - $200B): 10.05%Large Cap ($10B - $200B)Mid Cap ($2B - $10B): 43.97%Mid Cap ($2B - $10B)Small Cap ($300M - $2B): 23.62%Small Cap ($300M - $2B)Micro Cap ($50M - $300M): 8.15%Nano Cap (< $50M): 0.78%N/A (ETF or Unknown): 9.66%N/A (ETF or Unknown)
Mega Cap (> $200B)
3.77%
Large Cap ($10B - $200B)
10.05%
Mid Cap ($2B - $10B)
43.97%
Small Cap ($300M - $2B)
23.62%
Micro Cap ($50M - $300M)
8.15%
Nano Cap (< $50M)
0.78%
N/A (ETF or Unknown)
9.66%

Portfolio Concentration

Top 10 Holdings %
59.5%
Top 20 Holdings %
82.2%
Top 50 Holdings %
100.0%
Top 100 Holdings %
100.0%

Geographic Exposure

Portfolio breakdown by country of incorporation

Domestic (US)
89.42%
International
10.58%
Countries
6
Largest Int'l Market
Ireland - 5.12%
United States of America
89.42% ($353.3M)
46 holdings
Ireland
5.12% ($20.2M)
1 holdings
Canada
2.93% ($11.6M)
1 holdings
Jersey
1.35% ($5.3M)
1 holdings
Netherlands
1.12% ($4.4M)
1 holdings
Belgium
0.06% ($233.9K)
1 holdings

Holding Behavior

Investment patterns and position management analysis

Portfolio Stability & Commitment

Avg. Top 10
1.7 quarters
Avg. Top 20
1.8 quarters
Avg. All Positions
3.9 quarters
Median Holding Period
3 quarters
Persistence Rate
39.22%
Persistent Holdings Weight
26.26%
Persistent Positions
20
Longest Held
NextCure, Inc. Common Stock logo
NextCure, Inc. Common StockNXTC - 15 quarters

Position Sizing & Influence

Current Quarter

Avg. New Position
2.55%
Avg. Position Weight
1.96%
Largest Position
MAXIMUS, Inc. logo
MAXIMUS, Inc.MMS - 12.89%
Largest Ownership Stake
PMV Pharmaceuticals, Inc logo
PMV Pharmaceuticals, IncPMVP - 4.98%
Avg. Ownership Stake
0.97%
Ownership Stake >5%
0
Ownership Stake >1%
18

Historical (Since Q4 2014)

Avg. New Position
2.92%
Avg. Ownership Stake
1.37%
Largest Position
Cellectar Biosciences INC NEW logo
Cellectar Biosciences INC NEWCLRB - 81.66% (Q4 2020)
Largest Ownership Stake
Actinium Pharmaceuticals, Inc logo
Actinium Pharmaceuticals, IncATNM - 36.98% (Q2 2020)

Portfolio Turnover

Current Quarter

Turnover Ratio
37.4%
Value Traded
$147.62M
Positions Added
9
Positions Exited
12

Historical (Since Q4 2014)

Avg. Turnover Ratio
51.7%
Avg. Positions Added
11
Avg. Positions Exited
15
Highest Turnover
277.3%
Q2 2021
Lowest Turnover
15.9%
Q1 2021

Cookie Preferences

We use cookies for analytics. See our Privacy and Cookie Policy.