Sio Capital Management, LLC logo

Sio Capital Management, LLC

Hedge FundLong/Short

Sio Capital Management, LLC is a Long/Short Hedge Fund based in New York, NY led by Judah Zvi Drillick, reporting $1.1B in AUM as of Q3 2025 with 68% Healthcare concentration and 60% concentrated in top 10 holdings.

CEOJudah Zvi Drillick
Portfolio Value
$395.2M
Positions
51
Top Holding
MMS at 12.89%
Last Reported
Q3 2025
Address600 Third Avenue, 2nd Floor, New York, NY, 10016, United States

Top Holdings

Largest long holdings in Sio Capital Management, LLC's portfolio (59.5% of total portfolio)

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HoldingSectorPositionWeightTradedOwnership
Specialty Business Services
Industrials
$50.9M
12.89%
+$870.7K
Bought
0.99%
557.6K shares
Biotechnology
Healthcare
$38.9M
9.83%
+$38.9M
New
1.85%
786.5K shares
3
SNY
Unknown
Unknown
$26.6M
6.72%
+$17.7M
Bought
562.7K shares
Biotechnology
Healthcare
$22.7M
5.75%
+$13.4M
Bought
1.45%
577.8K shares
Biotechnology
Healthcare
$20.2M
5.12%
+$20.2M
Bought
0.41%
674.8K shares
Biotechnology
Healthcare
$18.8M
4.76%
0.82%
284.8K shares
Drug Manufacturers - General
Healthcare
$14.9M
3.77%
+$281.1K
Bought
0.01%
177.3K shares
Medical - Distribution
Healthcare
$14.5M
3.68%
+$14.5M
New
0.18%
219.2K shares
Medical - Healthcare Plans
Healthcare
$13.8M
3.50%
+$4.5M
Bought
0.08%
387.6K shares
10
Kenvue logo
Kenvue
KVUE
Household & Personal Products
Consumer Defensive
$13.7M
3.47%
+$13.7M
Bought
0.04%
844.0K shares

Changes

Portfolio activity, position movements, and quarter-over-quarter changes in Sio Capital Management, LLC's latest filing

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Market Value
$395.2M
Prior: $249.2M
Q/Q Change
+58.58%
+$146.0M
Net Flows % of MV
+6.52%
Turnover Ratio
37.36%
New Purchases
9 stocks
$90.6M
Added To
6 stocks
+$39.8M
Sold Out Of
12 stocks
$57.9M
Reduced Holdings
13 stocks
-$46.8M

Increased Positions

PositionShares Δ
New
New
New
New
New

Decreased Positions

PositionShares Δ
Sold
Sold
3
Annexon logo
Sold
Sold
Sold

Analytics

Portfolio insights and performance metrics for Sio Capital Management, LLC

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Sector Allocation

Healthcare: 68.20%HealthcareIndustrials: 12.90%IndustrialsConsumer Defensive: 3.50%
Healthcare
68.20%
Industrials
12.90%
Consumer Defensive
3.50%

Market Cap Distribution

Mega Cap (> $200B): 3.77%Large Cap ($10B - $200B): 10.05%Large Cap ($10B - $200B)Mid Cap ($2B - $10B): 43.97%Mid Cap ($2B - $10B)Small Cap ($300M - $2B): 23.62%Small Cap ($300M - $2B)Micro Cap ($50M - $300M): 8.15%Nano Cap (< $50M): 0.78%N/A (ETF or Unknown): 9.66%N/A (ETF or Unknown)
Mega Cap (> $200B)
3.77%
Large Cap ($10B - $200B)
10.05%
Mid Cap ($2B - $10B)
43.97%
Small Cap ($300M - $2B)
23.62%
Micro Cap ($50M - $300M)
8.15%
Nano Cap (< $50M)
0.78%
N/A (ETF or Unknown)
9.66%

Portfolio Concentration

Top 10 Holdings %
59.5%
Top 20 Holdings %
82.2%
Top 50 Holdings %
100.0%
Top 100 Holdings %
100.0%

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