CareDx

CDNA • NASDAQ

CareDx is a medical - diagnostics & research company in the healthcare sector on NASDAQ, with a market cap of $1.1B. As of Q3 2025, 101% of shares are held by 183 institutional investors, with BlackRock, Inc. as the largest holder at 8.96%.

Market Cap$1.1B

Medical - Diagnostics & Research

Healthcare

Employees643.0

Websitecaredx.com

Country

United States of America

Overview

Overview of institutional ownership in CDNA as of Q3 2025 with a market cap of $773.9M

All Institutions

Institutions: 183
Value Held: $778.7M
Shares Held: 53.6M
Avg Position: $4.3M
Median Position: $481.4K

Hedge Funds

Hedge Funds: 31
Value Held: $187.1M
Shares Held: 12.9M
Avg Position: $6.0M
Median Position: $2.7M

Ownership Breakdown

Institutional (non-HF)

76.44%

$591.6M

Hedge Funds

24.18%

$187.1M

Retail & Other

Based on market cap of $773.9M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in CDNA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$69.3M 0.00% of portfolio	8.96% 4.8M shares	Q1 2017 Held for 8y 8m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$54.5M 0.00% of portfolio	7.04% 3.7M shares	Q4 2014 Held for 10y 11m	$6.69T
BAMCO INC /NY/ Long Only Manager	Ronald Stephen Baron CEO	$45.9M 0.12% of portfolio	5.93% 3.2M shares	Q1 2024 Held for 1y 8m	$37.7B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$37.3M 0.00% of portfolio	4.82% 2.6M shares	Q1 2018 Held for 7y 8m	$2.88T
O Ophir Asset Management Pty Ltd Long Only Manager	Sandra Donnarumma COO	$32.0M 3.95% of portfolio	4.13% 2.2M shares	Q1 2025 Held for 8 months	$809.7M
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short	James Edward Flynn President	$31.9M 0.53% of portfolio	4.12% 2.2M shares	Q3 2025 Held for 2 months	$6.0B
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	$31.7M 1.28% of portfolio	4.10% 2.2M shares	Q3 2025 Held for 2 months	$2.5B
ARK Investment Management LLC ETF Provider	Catherine Duddy Wood CEO	$31.6M 0.19% of portfolio	4.08% 2.2M shares	Q2 2019 Held for 6y 5m	$16.5B
S Sumitomo Mitsui Trust Holdings, Inc. Institution	-	$25.3M 0.01% of portfolio	3.27% 1.7M shares	Q2 2019 Held for 6y 5m	$173.79B
Nikko Asset Management Americas, Inc. Long Only Manager	James Mark Beyer Wesley CEO	$25.3M 0.25% of portfolio	3.27% 1.7M shares	Q3 2019 Held for 6y 2m	$10.3B

Net Capital Flow

Institutional buying and selling activity for CDNA in Q3 2025

Traded: +$6.0M
Buyers: 100
Sellers: 101
Total Bought: +$177.5M
Total Sold: −$171.5M
Avg Position: $3.4M

Biggest Buyers

Institution	Net Bought	Current Position
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short	+$31.9M +2.2M shares	$31.9M 2.2M shares
B BRAIDWELL LP Hedge Fund•Multi-Strategy	+$31.7M +2.2M shares	$31.7M 2.2M shares
BAMCO INC /NY/ Long Only Manager	+$10.5M +719.5K shares	$45.9M 3.2M shares
K Kent Lake PR LLC Hedge Fund•Long/Short	+$8.0M +550.0K shares	$8.0M 550.0K shares
Nikko Asset Management Americas, Inc. Long Only Manager	+$7.3M +504.5K shares	$25.3M 1.7M shares
S Sumitomo Mitsui Trust Holdings, Inc. Institution	+$7.3M +503.1K shares	$25.3M 1.7M shares
STATE STREET CORP Institution	+$5.6M +386.3K shares	$37.3M 2.6M shares
Z Zweig-DiMenna Associates LLC Hedge Fund•Long/Short	+$5.1M +348.4K shares	$8.4M 575.0K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$5.0M +345.2K shares	$6.0M 413.7K shares
P Palo Alto Investors, LLC Hedge Fund•Long/Short	+$4.6M +316.2K shares	$4.6M 316.2K shares

Biggest Sellers

Institution	Net Sold	Current Position
Hood River Capital Management LLC Long Only Manager	−$34.5M −1.8M shares	Sold Off 0 shares
NEXT CENTURY GROWTH INVESTORS LLC Long Only Manager	−$22.0M −1.1M shares	Sold Off 0 shares
VANGUARD GROUP INC Institution	−$16.9M −1.2M shares	$54.5M 3.7M shares
SG Capital Management LLC Hedge Fund•Event Driven	−$6.2M −315.8K shares	Sold Off 0 shares
OBERWEIS ASSET MANAGEMENT INC/ Long Only Manager	−$5.7M −292.9K shares	Sold Off 0 shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	−$5.6M −388.3K shares	$10.2M 704.1K shares
Trexquant Investment LP Hedge Fund•Quant	−$5.5M −281.3K shares	Sold Off 0 shares
R ROYCE & ASSOCIATES LLC Institution	−$5.4M −374.2K shares	$5.9M 404.4K shares
F FRED ALGER MANAGEMENT INC Long Only Manager	−$4.4M −304.7K shares	$13.5M 929.0K shares
LORD, ABBETT & CO. LLC Long Only Manager	−$4.4M −224.6K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited CDNA in Q3 2025

New Positions: 14
New Value: $45.2M
Exited Positions: 42
Exited Value: $107.8M

New Positions

Institution	Position Value
B BRAIDWELL LP Hedge Fund•Multi-Strategy	$31.7M 2.2M shares
K Kent Lake PR LLC Hedge Fund•Long/Short	$8.0M 550.0K shares
P Palo Alto Investors, LLC Hedge Fund•Long/Short	$4.6M 316.2K shares
Palumbo Wealth Management LLC RIA/Wealth	$537.7K 37.0K shares
Advantage Alpha Capital Partners LP Hedge Fund•Market Neutral	$307.7K 21.2K shares
S State of Alaska, Department of Revenue Institution	$43.8K 3.0K shares
O Optiver Holding B.V. Institution	$1.8K 124.0 shares
A AMERICAN NATIONAL BANK Institution	$1.5K 100.0 shares
Larson Financial Group LLC RIA/Wealth	$1.1K 77.0 shares
Groupe la Francaise Fund of Funds	$784.0 62.0 shares

Exited Positions

Institution	Previous Position
Hood River Capital Management LLC Long Only Manager	$34.5M 1.8M shares
NEXT CENTURY GROWTH INVESTORS LLC Long Only Manager	$22.0M 1.1M shares
SG Capital Management LLC Hedge Fund•Event Driven	$6.2M 315.8K shares
OBERWEIS ASSET MANAGEMENT INC/ Long Only Manager	$5.7M 292.9K shares
Trexquant Investment LP Hedge Fund•Quant	$5.5M 281.3K shares
LORD, ABBETT & CO. LLC Long Only Manager	$4.4M 224.6K shares
Q Qube Research & Technologies Ltd Institution	$4.3M 220.2K shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	$3.1M 156.6K shares
VICTORY CAPITAL MANAGEMENT INC Long Only Manager	$2.4M 123.6K shares
M Meridiem Capital Partners LP Hedge Fund•Long/Short	$2.4M 123.4K shares

Options Activity

Institutions with the largest Call and Put options positions in CDNA as of Q3 2025

Call Positions: 3
Call Value: $1.9M
Put Positions: 2
Put Value: $837.5K

Call Positions

Institution	Position Value
J JANE STREET GROUP, LLC Institution	$1.0M 694.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$600.5K 413.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$267.5K 184.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$664.5K 457.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$173.0K 119.0 contracts

Most Committed Institutions

Institutions with CDNA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
P PARAGON ASSOCIATES & PARAGON ASSOCIATES II JOINT VENTURE Institution	-	11.02% $6.2M	0.80% 425.0K shares	Q1 2025 Held for 8 months	$56.1M
Blue Water Life Science Advisors, LLC RIA/Wealth	Nathaniel Thomas Cornell Managing Partner	6.77% $7.4M	0.96% 510.0K shares	Q2 2024 Held for 1y 5m	$109.6M
GAGNON SECURITIES LLC RIA/Wealth	Neil Joseph Gagnon CEO	5.09% $25.1M	3.25% 1.7M shares	Q3 2014 Held for 11y 2m	$493.8M
G Gagnon Advisors, LLC Hedge Fund•Long/Short	Neil Joseph Gagnon CEO	4.75% $7.7M	0.99% 529.4K shares	Q3 2014 Held for 11y 2m	$162.0M
K Kent Lake PR LLC Hedge Fund•Long/Short	Benjamin Natter Managing Partner	4.09% $8.0M	1.03% 550.0K shares	Q3 2025 Held for 2 months	$195.5M
O Ophir Asset Management Pty Ltd Long Only Manager	Sandra Donnarumma COO	3.95% $32.0M	4.13% 2.2M shares	Q1 2025 Held for 8 months	$809.7M
Prosight Management, LP Hedge Fund•Long/Short	William Lawrence Hawkins Managing Partner	1.95% $7.3M	0.95% 504.0K shares	Q4 2024 Held for 11 months	$376.7M
Bullseye Asset Management LLC Hedge Fund•Long/Short	Jakob Vincent Holm Member	1.72% $3.3M	0.42% 225.5K shares	Q2 2020 Held for 5y 5m	$191.0M
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	1.28% $31.7M	4.10% 2.2M shares	Q3 2025 Held for 2 months	$2.5B
FORMULA GROWTH LTD Hedge Fund•Long/Short	Randall William Kelly President	0.97% $2.8M	0.36% 192.3K shares	Q4 2024 Held for 11 months	$288.3M

Hedge Fund Spotlight

Discover hedge funds investing in CDNA

Zweig-DiMenna Associates LLC

Hedge Fund • Long/Short

Portfolio ManagerKevin P Cannon

Portfolio Value: $1.3B
Positions: 93
Last Reported: Q3 2025

Sector Allocation

Position in CareDx

Market Value: $8.4M
Shares Held: 575.0K
Portfolio Weight: 0.66%
Owned Since: 2025-Q2

Top Holding	Sector	Market Value	Weight
1 Applovin Corporation APP	Software - Application Technology	$81.3M	6.37%
2 Amazon AMZN	Specialty Retail Consumer Cyclical	$79.4M	6.22%
3 Broadcom Inc. AVGO	Semiconductors Technology	$69.5M	5.45%