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Partner Fund Management, L.P.

Hedge FundSector

Partner Fund Management, L.P. is a Sector-focused Hedge Fund based in San Francisco, CA led by Jonathan Jude Aljoe, reporting $2.0B in AUM as of Q3 2025 with 91% Healthcare concentration and 52% concentrated in top 10 holdings.

CFOJonathan Jude Aljoe
Portfolio Value
$1.2B
Positions
66
Top Holding
LLY at 14.85%
Last Reported
Q3 2025
Address475 Sansome Street, Suite 1720, San Francisco, CA, 94111, United States

Top Holdings

Largest long holdings in Partner Fund Management, L.P.'s portfolio (51.6% of total portfolio)

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HoldingSectorPositionWeightTradedOwnership
Drug Manufacturers - General
Healthcare
$171.8M
14.85%
-$32.7M
Sold
0.03%
225.1K shares
Medical - Care Facilities
Healthcare
$93.7M
8.10%
-$7.6M
Sold
0.52%
461.7K shares
Biotechnology
Healthcare
$64.4M
5.57%
+$5.7M
Bought
1.06%
530.3K shares
Medical - Distribution
Healthcare
$55.9M
4.83%
0.06%
72.3K shares
Medical - Devices
Healthcare
$49.4M
4.27%
+$7.3M
Bought
0.50%
195.1K shares
Biotechnology
Healthcare
$40.1M
3.47%
+$24.8M
Bought
0.21%
95.7K shares
Medical - Instruments & Supplies
Healthcare
$34.6M
2.99%
-$5.2M
Sold
0.02%
77.4K shares
Medical - Devices
Healthcare
$29.7M
2.56%
-$869.4K
Sold
0.06%
381.3K shares
Unknown
Unknown
$28.9M
2.50%
-$15.2M
Sold
145.3K shares
Medical - Care Facilities
Healthcare
$28.0M
2.42%
-$2.8M
Sold
0.03%
65.8K shares

Changes

Portfolio activity, position movements, and quarter-over-quarter changes in Partner Fund Management, L.P.'s latest filing

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Market Value
$1.2B
Prior: $1.1B
Q/Q Change
+2.79%
+$31.4M
Net Flows % of MV
-16.98%
Turnover Ratio
26.74%
New Purchases
10 stocks
$59.0M
Added To
16 stocks
+$92.8M
Sold Out Of
12 stocks
$149.9M
Reduced Holdings
23 stocks
-$198.4M

Increased Positions

PositionShares Δ
New
New
New
New
New

Decreased Positions

PositionShares Δ
Sold
Sold
Sold
4
Masimo logo
Masimo
MASI
Sold
5
Hologic logo
Sold

Analytics

Portfolio insights and performance metrics for Partner Fund Management, L.P.

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Sector Allocation

Healthcare: 91.20%HealthcareETF: 1.20%Consumer Defensive: 0.10%
Healthcare
91.20%
ETF
1.20%
Consumer Defensive
0.10%

Market Cap Distribution

Mega Cap (> $200B): 16.56%Mega Cap (> $200B)Large Cap ($10B - $200B): 40.70%Large Cap ($10B - $200B)Mid Cap ($2B - $10B): 23.83%Mid Cap ($2B - $10B)Small Cap ($300M - $2B): 5.88%Micro Cap ($50M - $300M): 2.45%Nano Cap (< $50M): 2.17%N/A (ETF or Unknown): 8.40%N/A (ETF or Unknown)
Mega Cap (> $200B)
16.56%
Large Cap ($10B - $200B)
40.70%
Mid Cap ($2B - $10B)
23.83%
Small Cap ($300M - $2B)
5.88%
Micro Cap ($50M - $300M)
2.45%
Nano Cap (< $50M)
2.17%
N/A (ETF or Unknown)
8.40%

Portfolio Concentration

Top 10 Holdings %
51.56%
Top 20 Holdings %
70.47%
Top 50 Holdings %
96.58%
Top 100 Holdings %
100.0%

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