TRV GP IV, LLC Portfolio Holdings

Q3 2025•2 long positions•$274.0M portfolio value

Holding3	Sector	Position↕	Traded↕	Ownership↕	Shares Δ↕	Shares Δ %	Market Cap↕	Owned Since↕
1 Maze Therapeutics, Inc. Common Stock MAZE	Unknown Unknown	$157.5M 57.49%	—	13.85% 6.1M shares	—	—	$1.1B Small Cap	Q1 2025 Held for 8 months
2 Tango Therapeutics TNGX	Biotechnology Healthcare	$116.5M 42.51%	-$25.2M Sold	12.46% 13.9M shares	16.9M → 13.9M −$25.2M	-17.77%	$934.6M Small Cap	Q3 2021 Held for 4y 2m
3 Pliant Therapeutics PLRX	Biotechnology Healthcare	- —	-$2.5M Sold	— - shares	2.1M → 0 −$2.5M	Sold	$79.8M Micro Cap	Q2 2020 Held for 5y 5m

Holding3	Sector	Position↕	Traded↕	Ownership↕	Shares Δ↕	Shares Δ %	Market Cap↕	Owned Since↕
1 Maze Therapeutics, Inc. Common Stock MAZE	Unknown Unknown	$157.5M 57.49%	—	13.85% 6.1M shares	—	—	$1.1B Small Cap	Q1 2025 Held for 8 months
2 Tango Therapeutics TNGX	Biotechnology Healthcare	$116.5M 42.51%	-$25.2M Sold	12.46% 13.9M shares	16.9M → 13.9M −$25.2M	-17.77%	$934.6M Small Cap	Q3 2021 Held for 4y 2m
3 Pliant Therapeutics PLRX	Biotechnology Healthcare	- —	-$2.5M Sold	— - shares	2.1M → 0 −$2.5M	Sold	$79.8M Micro Cap	Q2 2020 Held for 5y 5m

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