Pliant Therapeutics

PLRX • NASDAQ

Pliant Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by Steve Krognes, with a market cap of $75.6M. As of Q3 2025, 82% of shares are held by 96 institutional investors, with TANG CAPITAL MANAGEMENT LLC as the largest holder at 9.78%.

DirectorSteve Krognes

Market Cap$75.6M

Biotechnology

Healthcare

Employees158.0

Websitepliantrx.com

Country

United States of America

Overview

Overview of institutional ownership in PLRX as of Q3 2025 with a market cap of $90.9M

All Institutions

Institutions: 96
Value Held: $74.6M
Shares Held: 50.4M
Avg Position: $776.7K
Median Position: $99.3K

Hedge Funds

Hedge Funds: 21
Value Held: $27.0M
Shares Held: 18.3M
Avg Position: $1.3M
Median Position: $416.2K

Ownership Breakdown

Institutional (non-HF)

52.31%

$47.5M

Hedge Funds

29.76%

$27.0M

Retail & Other

17.93%

$16.3M

Based on market cap of $90.9M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in PLRX as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
T TANG CAPITAL MANAGEMENT LLC Institution	-	$8.9M 0.35% of portfolio	9.78% 6.0M shares	Q1 2025 Held for 8 months	$2.5B
Woodline Partners LP Hedge Fund•Long/Short	Karl Heinz Kroeker CIO	$6.7M 0.03% of portfolio	7.34% 4.5M shares	Q2 2023 Held for 2y 5m	$21.3B
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	Steven Alan Cohen CEO	$6.4M 0.01% of portfolio	7.07% 4.3M shares	Q3 2025 Held for 2 months	$43.2B
MORGAN STANLEY RIA/Wealth	Jed Finn CEO	$5.2M 0.00% of portfolio	5.71% 3.5M shares	Q2 2020 Held for 5y 5m	$1.65T
B Blue Owl Capital Holdings LP Institution	-	$4.4M 1.38% of portfolio	4.84% 3.0M shares	Q4 2023 Held for 1y 11m	$318.8M
VANGUARD GROUP INC Institution	Salim Ramji CEO	$4.1M 0.00% of portfolio	4.52% 2.8M shares	Q2 2020 Held for 5y 5m	$6.69T
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	Gillian Morna Therese Savage CEO	$3.5M 0.01% of portfolio	3.86% 2.4M shares	Q1 2025 Held for 8 months	$51.5B
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	Kenneth Cordele Griffin CEO	$3.5M 0.00% of portfolio	3.81% 2.3M shares	Q2 2020 Held for 5y 5m	$122.08B
JPMORGAN CHASE & CO Institution	Jamie Dimon CEO	$3.2M 0.00% of portfolio	3.47% 2.1M shares	Q3 2020 Held for 5y 2m	$1.56T
R Redmile Group, LLC Hedge Fund•Sector	Amrit Nmn Nagpal Managing Partner	$2.4M 0.23% of portfolio	2.59% 1.6M shares	Q2 2020 Held for 5y 5m	$1.0B

Net Capital Flow

Institutional buying and selling activity for PLRX in Q3 2025

Traded: +$2.8M
Buyers: 36
Sellers: 65
Total Bought: +$19.1M
Total Sold: −$16.3M
Avg Position: $601.3K

Biggest Buyers

Institution	Net Bought	Current Position
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$6.4M +4.3M shares	$6.4M 4.3M shares
Woodline Partners LP Hedge Fund•Long/Short	+$3.2M +2.2M shares	$6.7M 4.5M shares
Eversept Partners, LLC Hedge Fund•Long/Short	+$1.2M +824.6K shares	$1.2M 824.6K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	+$1.2M +811.9K shares	$1.5M 1.0M shares
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	+$1.1M +739.1K shares	$3.5M 2.4M shares
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy	+$913.6K +617.3K shares	$1.6M 1.1M shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$747.5K +505.1K shares	$1.2M 783.3K shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	+$543.3K +367.1K shares	$543.3K 367.1K shares
BARCLAYS PLC Institution	+$527.9K +356.7K shares	$546.9K 369.6K shares
Marshall Wace LLP Institution	+$443.2K +299.5K shares	$443.2K 299.5K shares

Biggest Sellers

Institution	Net Sold	Current Position
Deep Track Capital, LP Hedge Fund•Long/Short	−$4.6M −3.9M shares	Sold Off 0 shares
Madison Avenue Partners, LP Hedge Fund•Value	−$2.6M −2.2M shares	Sold Off 0 shares
T TRV GP IV, LLC Institution	−$2.5M −2.1M shares	Sold Off 0 shares
UBS Group AG Institution	−$2.0M −1.3M shares	$2.0M 1.3M shares
B BlackRock, Inc. Institution	−$1.1M −709.7K shares	$2.1M 1.4M shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$463.4K −313.1K shares	$795.3K 537.3K shares
MORGAN STANLEY RIA/Wealth	−$364.6K −246.3K shares	$5.2M 3.5M shares
VANGUARD GROUP INC Institution	−$335.1K −226.4K shares	$4.1M 2.8M shares
C Cubist Systematic Strategies, LLC Institution	−$316.7K −214.0K shares	$80.5K 54.4K shares
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	−$291.6K −251.4K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited PLRX in Q3 2025

New Positions: 5
New Value: $625.8K
Exited Positions: 26
Exited Value: $10.5M

New Positions

Institution	Position Value
S Stonepine Capital Management, LLC Institution	$428.1K 289.2K shares
T TORNO CAPITAL, LLC Institution	$193.8K 130.9K shares
Fortitude Family Office, LLC Family Office	$1.9K 1.3K shares
Rockefeller Capital Management L.P. Long Only Manager	$1.6K 1.1K shares
Bell Investment Advisors, Inc RIA/Wealth	$455.0 307.0 shares

Exited Positions

Institution	Previous Position
Deep Track Capital, LP Hedge Fund•Long/Short	$4.6M 3.9M shares
Madison Avenue Partners, LP Hedge Fund•Value	$2.6M 2.2M shares
T TRV GP IV, LLC Institution	$2.5M 2.1M shares
SCHWAB CHARLES INVESTMENT MANAGEMENT INC Long Only Manager	$291.6K 251.4K shares
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	$97.3K 83.9K shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	$95.3K 82.2K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	$62.3K 53.7K shares
O OXFORD ASSET MANAGEMENT Institution	$38.3K 33.0K shares
H HRT FINANCIAL LLC Institution	$37.7K 32.5K shares
C CANADA PENSION PLAN INVESTMENT BOARD Institution	$35.7K 30.8K shares

Options Activity

Institutions with the largest Call and Put options positions in PLRX as of Q3 2025

Call Positions: 2
Call Value: $105.1K
Put Positions: 2
Put Value: $150.5K

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$83.6K 565.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$21.5K 145.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$127.7K 863.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$22.8K 154.0 contracts

Most Committed Institutions

Institutions with PLRX as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
P Peapod Lane Capital LLC Institution	-	1.45% $1.6M	1.79% 1.1M shares	Q1 2025 Held for 8 months	$111.8M
B Blue Owl Capital Holdings LP Institution	-	1.38% $4.4M	4.84% 3.0M shares	Q4 2023 Held for 1y 11m	$318.8M
G GREAT POINT PARTNERS LLC Private Equity	Jeffrey Robert Jay Managing Partner	0.55% $1.3M	1.38% 850.0K shares	Q2 2022 Held for 3y 5m	$226.8M
Monaco Asset Management SAM RIA/Wealth	Kirstin Lynn Hark Director	0.47% $1.2M	1.34% 822.7K shares	Q2 2025 Held for 5 months	$256.5M
T TANG CAPITAL MANAGEMENT LLC Institution	-	0.35% $8.9M	9.78% 6.0M shares	Q1 2025 Held for 8 months	$2.5B
S Stonepine Capital Management, LLC Institution	-	0.35% $428.1K	0.47% 289.2K shares	Q3 2025 Held for 2 months	$123.0M
R Redmile Group, LLC Hedge Fund•Sector	Amrit Nmn Nagpal Managing Partner	0.23% $2.4M	2.59% 1.6M shares	Q2 2020 Held for 5y 5m	$1.0B
H HighMark Wealth Management LLC RIA/Wealth	Todd Edward Arens Managing Partner	0.14% $324.1K	0.36% 219.0K shares	Q4 2023 Held for 1y 11m	$227.1M
Eversept Partners, LLC Hedge Fund•Long/Short	Rishi Rasesh Shah President	0.09% $1.2M	1.34% 824.6K shares	Q3 2025 Held for 2 months	$1.3B
R Rangeley Capital, LLC Hedge Fund•Event Driven	Christopher Clay Demuth Jr. Managing Partner	0.08% $89.1K	0.10% 60.2K shares	Q1 2025 Held for 8 months	$105.5M

Hedge Fund Spotlight

Discover hedge funds investing in PLRX

CITADEL ADVISORS LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerKenneth Cordele Griffin

Portfolio Value: $122.08B
Positions: 5,531
Last Reported: Q3 2025

Sector Allocation

Position in Pliant Therapeutics

Market Value: $3.5M
Shares Held: 2.3M
Portfolio Weight: 0.00%
Owned Since: 2020-Q2

Top Holding	Sector	Market Value	Weight
1 Microsoft MSFT	Software - Infrastructure Technology	$2.1B	1.68%
2 Nvidia NVDA	Semiconductors Technology	$1.8B	1.50%
3 Meta Platforms, Inc. META	Internet Content & Information Communication Services	$1.4B	1.18%