Maze Therapeutics, Inc. Common Stock

MAZE • NASDAQ

Maze Therapeutics, Inc. Common Stock is a publicly traded company on NASDAQ, with a market cap of $1.9B. As of Q3 2025, 98% of shares are held by 93 institutional investors, with TRV GP IV, LLC as the largest holder at 13.85%.

Market Cap$1.9B

Websitemazetx.com

Overview

Overview of institutional ownership in MAZE as of Q3 2025 with a market cap of $1.1B

All Institutions

Institutions: 93
Value Held: $1.1B
Shares Held: 43.0M
Avg Position: $12.0M
Median Position: $785.8K

Hedge Funds

Hedge Funds: 19
Value Held: $300.4M
Shares Held: 11.6M
Avg Position: $15.8M
Median Position: $5.2M

Ownership Breakdown

Institutional (non-HF)

71.57%

$813.8M

Hedge Funds

26.42%

$300.4M

Retail & Other

2.01%

$22.8M

Based on market cap of $1.1B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in MAZE as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
T TRV GP IV, LLC Institution	-	$157.5M 57.49% of portfolio	13.85% 6.1M shares	Q1 2025 Held for 8 months	$274.0M
Frazier Life Sciences Management, L.P. Venture Capital	James Newman Topper Managing Partner	$118.4M 3.55% of portfolio	10.42% 4.6M shares	Q1 2025 Held for 8 months	$3.3B
A ARCH VENTURE CORP Institution	-	$106.8M 21.70% of portfolio	9.40% 4.1M shares	Q1 2025 Held for 8 months	$492.4M
Deep Track Capital, LP Hedge Fund•Long/Short	David Eric Kroin CIO	$102.4M 2.91% of portfolio	9.01% 3.9M shares	Q1 2025 Held for 8 months	$3.5B
Alphabet Inc. Institution	Sundar Pichai CEO	$62.6M 2.60% of portfolio	5.50% 2.4M shares	Q1 2025 Held for 8 months	$2.4B
A AH Capital Management, L.L.C. Institution	-	$44.1M 3.17% of portfolio	3.88% 1.7M shares	Q1 2025 Held for 8 months	$1.4B
M Matrix Capital Management Company, LLC Hedge Fund•Long/Short	Christopher David Johnson CFO	$42.9M 40.17% of portfolio	3.77% 1.7M shares	Q1 2025 Held for 8 months	$106.7M
VANGUARD GROUP INC Institution	Salim Ramji CEO	$34.6M 0.00% of portfolio	3.04% 1.3M shares	Q1 2025 Held for 8 months	$6.69T
B BlackRock, Inc. Institution	-	$34.1M 0.00% of portfolio	3.00% 1.3M shares	Q1 2025 Held for 8 months	$5.67T
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	$31.9M 1.80% of portfolio	2.81% 1.2M shares	Q3 2025 Held for 2 months	$1.8B

Net Capital Flow

Institutional buying and selling activity for MAZE in Q3 2025

Traded: +$108.9M
Buyers: 63
Sellers: 17
Total Bought: +$216.8M
Total Sold: −$107.9M
Avg Position: $11.6M

Biggest Buyers

Institution	Net Bought	Current Position
VR Adviser, LLC Venture Capital	+$31.9M +1.2M shares	$31.9M 1.2M shares
VANGUARD GROUP INC Institution	+$23.7M +915.3K shares	$34.6M 1.3M shares
Marshall Wace LLP Institution	+$19.7M +758.1K shares	$20.2M 777.7K shares
B BlackRock, Inc. Institution	+$18.2M +701.3K shares	$34.1M 1.3M shares
Logos Global Management LP Hedge Fund•Long/Short	+$16.0M +615.4K shares	$31.8M 1.2M shares
A Arrowpoint Asset Management, LLC Hedge Fund•Multi-Strategy	+$14.1M +545.1K shares	$14.1M 545.1K shares
Ikarian Capital, LLC Hedge Fund•Event Driven	+$12.4M +478.1K shares	$19.2M 740.8K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$11.2M +433.7K shares	$11.2M 433.7K shares
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	+$7.2M +276.3K shares	$9.1M 351.9K shares
GEODE CAPITAL MANAGEMENT LLC ETF Provider	+$6.3M +242.3K shares	$12.3M 473.5K shares

Biggest Sellers

Institution	Net Sold	Current Position
Foresite Capital Management IV, LLC Venture Capital	−$41.2M −1.6M shares	$13.6M 522.7K shares
M Matrix Capital Management Company, LLC Hedge Fund•Long/Short	−$21.6M −832.5K shares	$42.9M 1.7M shares
HENDERSON GROUP PLC Institution	−$16.8M −649.4K shares	$19.5M 751.9K shares
H HARVARD MANAGEMENT CO INC Institution	−$14.1M −545.1K shares	$2.4M 92.4K shares
Foresite Capital Management V, LLC Venture Capital	−$6.7M −258.9K shares	$2.2M 86.3K shares
S SPHERA FUNDS MANAGEMENT LTD. Institution	−$5.2M −202.1K shares	$4.0M 154.3K shares
S STRS OHIO Institution	−$752.0K −29.0K shares	$464.1K 17.9K shares
UBS Group AG Institution	−$612.2K −23.6K shares	$720.7K 27.8K shares
Ghisallo Capital Management LLC Hedge Fund•Multi-Strategy	−$368.1K −30.0K shares	Sold Off 0 shares
A ALPS ADVISORS INC ETF Provider	−$255.0K −9.8K shares	$356.3K 13.7K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited MAZE in Q3 2025

New Positions: 23
New Value: $78.9M
Exited Positions: 3
Exited Value: $493.4K

New Positions

Institution	Position Value
VR Adviser, LLC Venture Capital	$31.9M 1.2M shares
A Arrowpoint Asset Management, LLC Hedge Fund•Multi-Strategy	$14.1M 545.1K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$11.2M 433.7K shares
W WASHINGTON UNIVERSITY Institution	$5.5M 210.7K shares
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	$5.2M 200.0K shares
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy	$3.0M 114.0K shares
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	$2.4M 93.4K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	$2.2M 86.1K shares
X XTX Topco Ltd Institution	$696.7K 26.9K shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	$675.3K 26.0K shares

Exited Positions

Institution	Previous Position
Ghisallo Capital Management LLC Hedge Fund•Multi-Strategy	$368.1K 30.0K shares
Engineers Gate Manager LP Hedge Fund•Quant	$125.3K 10.2K shares
IFP Advisors, Inc RIA/Wealth	$37.0 3.0 shares

Options Activity

Institutions with the largest Call and Put options positions in MAZE as of Q3 2025

Call Positions: 0
Call Value: -
Put Positions: 1
Put Value: $777.9K

Call Positions

Institution	Position Value
No call positions found

Put Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$777.9K 300.0 contracts

Most Committed Institutions

Institutions with MAZE as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
T TRV GP IV, LLC Institution	-	57.49% $157.5M	13.85% 6.1M shares	Q1 2025 Held for 8 months	$274.0M
M Matrix Capital Management Company, LLC Hedge Fund•Long/Short	Christopher David Johnson CFO	40.17% $42.9M	3.77% 1.7M shares	Q1 2025 Held for 8 months	$106.7M
A ARCH VENTURE CORP Institution	-	21.70% $106.8M	9.40% 4.1M shares	Q1 2025 Held for 8 months	$492.4M
Foresite Capital Management IV, LLC Venture Capital	James Bruce Tananbaum CEO	7.42% $13.6M	1.19% 522.7K shares	Q1 2025 Held for 8 months	$182.6M
T TRV GP V, LLC Institution	-	6.97% $24.7M	2.17% 950.8K shares	Q1 2025 Held for 8 months	$353.5M
Ikarian Capital, LLC Hedge Fund•Event Driven	Neil Tristan Shahrestani CEO	3.89% $19.2M	1.69% 740.8K shares	Q1 2025 Held for 8 months	$494.3M
Frazier Life Sciences Management, L.P. Venture Capital	James Newman Topper Managing Partner	3.55% $118.4M	10.42% 4.6M shares	Q1 2025 Held for 8 months	$3.3B
Logos Global Management LP Hedge Fund•Long/Short	Graham Gordon Walmsley Managing Partner	3.22% $31.8M	2.80% 1.2M shares	Q1 2025 Held for 8 months	$987.5M
A AH Capital Management, L.L.C. Institution	-	3.17% $44.1M	3.88% 1.7M shares	Q1 2025 Held for 8 months	$1.4B
W WASHINGTON UNIVERSITY Institution	-	3.06% $5.5M	0.48% 210.7K shares	Q3 2025 Held for 2 months	$178.5M

Hedge Fund Spotlight

Discover hedge funds investing in MAZE

Caption Management, LLC

Hedge Fund • Long/Short

Portfolio ManagerWilliam Lamblè Cooper

Portfolio Value: $1.7B
Positions: 576
Last Reported: Q3 2025

Sector Allocation

Position in Maze Therapeutics, Inc. Common Stock

Market Value: $103.7K
Shares Held: 4.0K
Portfolio Weight: 0.01%
Owned Since: 2025-Q3

Top Holding	Sector	Market Value	Weight
1 Tesla, Inc. TSLA	Auto - Manufacturers Consumer Cyclical	$155.7M	9.09%
2 Amazon AMZN	Specialty Retail Consumer Cyclical	$126.3M	7.38%
3 Nvidia NVDA	Semiconductors Technology	$93.3M	5.45%