Nuvation Bio

NUVB • NYSE

Nuvation Bio is a biotechnology company in the healthcare sector on NYSE, led by David Hung, M.D., with a market cap of $2.9B. As of Q3 2025, 65% of shares are held by 198 institutional investors, with FMR LLC as the largest holder at 14.77%.

President and Chief Executive OfficerDavid Hung, M.D.

Market Cap$2.9B

Biotechnology

Healthcare

Employees159.0

Websitenuvationbio.com

Country

United States of America

Overview

Overview of institutional ownership in NUVB as of Q3 2025 with a market cap of $1.3B

All Institutions

Institutions: 198
Value Held: $817.7M
Shares Held: 220.5M
Avg Position: $4.1M
Median Position: $224.7K

Hedge Funds

Hedge Funds: 25
Value Held: $141.5M
Shares Held: 38.2M
Avg Position: $5.7M
Median Position: $3.2M

Ownership Breakdown

Institutional (non-HF)

53.39%

$676.2M

Hedge Funds

11.18%

$141.5M

Retail & Other

35.43%

$448.7M

Based on market cap of $1.3B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in NUVB as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
FMR LLC Institution	-	$187.1M 0.01% of portfolio	14.77% 50.6M shares	Q1 2021 Held for 4y 8m	$1.92T
Decheng Capital LLC Venture Capital	Xiangmin Nmn Cui Managing Partner	$96.0M 16.75% of portfolio	7.58% 26.0M shares	Q2 2024 Held for 1y 5m	$573.2M
B BlackRock, Inc. Institution	-	$91.0M 0.00% of portfolio	7.19% 24.6M shares	Q1 2021 Held for 4y 8m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$57.2M 0.00% of portfolio	4.52% 15.5M shares	Q1 2021 Held for 4y 8m	$6.69T
Laurion Capital Management LP Hedge Fund•Multi-Strategy	Masih Mohebbi-Forushani CFO	$35.9M 5.28% of portfolio	2.84% 9.7M shares	Q2 2024 Held for 1y 5m	$679.7M
Omega Fund Management Inc. Venture Capital	Alexandra Rankel Pearsall CFO	$32.7M 14.69% of portfolio	2.58% 8.8M shares	Q1 2021 Held for 4y 8m	$222.4M
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$22.5M 0.00% of portfolio	1.78% 6.1M shares	Q1 2021 Held for 4y 8m	$2.88T
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$21.8M 0.00% of portfolio	1.72% 5.9M shares	Q1 2021 Held for 4y 8m	$1.57T
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$18.0M 0.01% of portfolio	1.42% 4.9M shares	Q2 2022 Held for 3y 5m	$121.98B
N Nuveen, LLC Institution	-	$16.9M 0.00% of portfolio	1.33% 4.6M shares	Q1 2025 Held for 8 months	$377.89B

Net Capital Flow

Institutional buying and selling activity for NUVB in Q3 2025

Traded: −$1.5M
Buyers: 119
Sellers: 64
Total Bought: +$78.7M
Total Sold: −$80.2M
Avg Position: $3.8M

Biggest Buyers

Institution	Net Bought	Current Position
N Nuveen, LLC Institution	+$11.4M +3.1M shares	$16.9M 4.6M shares
J JANE STREET GROUP, LLC Institution	+$8.6M +2.3M shares	$8.6M 2.3M shares
ARMISTICE CAPITAL, LLC Hedge Fund•Long/Short	+$6.6M +1.8M shares	$8.5M 2.3M shares
P Pale Fire Capital SE Institution	+$5.0M +1.3M shares	$5.3M 1.4M shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$4.3M +1.2M shares	$8.8M 2.4M shares
Woodline Partners LP Hedge Fund•Long/Short	+$3.5M +955.4K shares	$3.5M 955.4K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$3.3M +896.9K shares	$7.5M 2.0M shares
TANAKA CAPITAL MANAGEMENT INC RIA/Wealth	+$2.5M +685.1K shares	$2.5M 685.1K shares
H HRT FINANCIAL LLC Institution	+$2.3M +631.2K shares	$2.3M 631.2K shares
JPMORGAN CHASE & CO Institution	+$2.1M +557.7K shares	$2.5M 675.6K shares

Biggest Sellers

Institution	Net Sold	Current Position
Octagon Capital Advisors LP Hedge Fund•Sector	−$18.7M −5.1M shares	$9.7M 2.6M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$11.9M −3.2M shares	$8.5M 2.3M shares
MPM Oncology Impact Management LP Institution	−$9.0M −4.6M shares	Sold Off 0 shares
Omega Fund Management Inc. Venture Capital	−$8.2M −2.2M shares	$32.7M 8.8M shares
B BlackRock, Inc. Institution	−$4.2M −1.1M shares	$91.0M 24.6M shares
Marshall Wace LLP Institution	−$2.4M −661.2K shares	$777.0K 210.0K shares
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant	−$2.2M −591.9K shares	$3.8M 1.0M shares
Laurion Capital Management LP Hedge Fund•Multi-Strategy	−$2.0M −535.2K shares	$35.9M 9.7M shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$2.0M −528.0K shares	$18.0M 4.9M shares
BARCLAYS PLC Institution	−$1.9M −523.6K shares	$1.8M 495.9K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited NUVB in Q3 2025

New Positions: 23
New Value: $9.6M
Exited Positions: 16
Exited Value: $15.6M

New Positions

Institution	Position Value
Woodline Partners LP Hedge Fund•Long/Short	$3.5M 955.4K shares
TANAKA CAPITAL MANAGEMENT INC RIA/Wealth	$2.5M 685.1K shares
C CAXTON ASSOCIATES LLP Institution	$711.5K 192.3K shares
Q Quarry LP Institution	$696.7K 188.3K shares
Q Quadrature Capital Ltd Institution	$459.8K 124.4K shares
O OMERS ADMINISTRATION Corp Institution	$376.3K 101.7K shares
Connective Capital Management, LLC Hedge Fund•Long/Short	$368.6K 99.6K shares
MERCER GLOBAL ADVISORS INC /ADV RIA/Wealth	$118.8K 32.1K shares
SAPIENT CAPITAL LLC RIA/Wealth	$101.3K 31.5K shares
E EHP Funds Inc. Institution	$93.1K 25.2K shares

Exited Positions

Institution	Previous Position
MPM Oncology Impact Management LP Institution	$9.0M 4.6M shares
N NATIXIS Institution	$1.8M 905.5K shares
ALGERT COLDIRON INVESTORS LLC Hedge Fund•Quant	$1.5M 781.2K shares
Ikarian Capital, LLC Hedge Fund•Event Driven	$1.2M 619.3K shares
X-Square Capital, LLC Long Only Manager	$604.5K 310.0K shares
UBS OCONNOR LLC Long Only Manager	$550.8K 282.5K shares
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$365.8K 187.6K shares
S Stonepine Capital Management, LLC Institution	$166.3K 85.3K shares
D DRW Securities, LLC Institution	$164.3K 84.2K shares
ENVESTNET ASSET MANAGEMENT INC Long Only Manager	$92.5K 47.4K shares

Options Activity

Institutions with the largest Call and Put options positions in NUVB as of Q3 2025

Call Positions: 4
Call Value: $7.3M
Put Positions: 3
Put Value: $2.4M

Call Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$7.0M 18.9K contracts
J JANE STREET GROUP, LLC Institution	$207.9K 562.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$79.9K 216.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$52.2K 141.0 contracts

Put Positions

Institution	Position Value
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.2M 3.3K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$919.1K 2.5K contracts
J JANE STREET GROUP, LLC Institution	$310.8K 840.0 contracts

Most Committed Institutions

Institutions with NUVB as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Decheng Capital LLC Venture Capital	Xiangmin Nmn Cui Managing Partner	16.75% $96.0M	7.58% 26.0M shares	Q2 2024 Held for 1y 5m	$573.2M
Omega Fund Management Inc. Venture Capital	Alexandra Rankel Pearsall CFO	14.69% $32.7M	2.58% 8.8M shares	Q1 2021 Held for 4y 8m	$222.4M
Laurion Capital Management LP Hedge Fund•Multi-Strategy	Masih Mohebbi-Forushani CFO	5.28% $35.9M	2.84% 9.7M shares	Q2 2024 Held for 1y 5m	$679.7M
TANAKA CAPITAL MANAGEMENT INC RIA/Wealth	Graham Yoshio Tanaka President	3.69% $2.5M	0.20% 685.1K shares	Q3 2025 Held for 2 months	$68.8M
K Knoll Capital Management, LP Institution	-	2.97% $5.5M	0.30% 1.0M shares	Q1 2025 Held for 8 months	$186.6M
A Aisling Capital Management LP Private Equity	Steven Arnote Elms President	2.40% $11.0M	0.86% 3.0M shares	Q1 2021 Held for 4y 8m	$456.4M
Octagon Capital Advisors LP Hedge Fund•Sector	Ting (Nmn) Jia Founder	1.53% $9.7M	0.77% 2.6M shares	Q4 2023 Held for 1y 11m	$637.4M
R Redmile Group, LLC Hedge Fund•Sector	Amrit Nmn Nagpal Managing Partner	1.09% $11.2M	0.89% 3.0M shares	Q1 2021 Held for 4y 8m	$1.0B
P Palo Alto Investors, LLC Hedge Fund•Long/Short	Angela Elizabeth Nguyen-Dinh CCO	0.70% $3.8M	0.30% 1.0M shares	Q1 2024 Held for 1y 8m	$540.4M
T TANG CAPITAL MANAGEMENT LLC Institution	-	0.61% $15.5M	1.23% 4.2M shares	Q4 2023 Held for 1y 11m	$2.5B