Acadia Pharmaceuticals

ACAD • NASDAQ

Acadia Pharmaceuticals is a biotechnology company in the healthcare sector on NASDAQ, led by Catherine Owen Adams, with a market cap of $4.6B. As of Q3 2025, 99% of shares are held by 325 institutional investors, with BAKER BROS. ADVISORS LP as the largest holder at 25.43%.

Chief Executive OfficerCatherine Owen Adams

Market Cap$4.6B

Biotechnology

Healthcare

Employees610.0

Websiteacadia.com

Country

United States of America

Overview

Overview of institutional ownership in ACAD as of Q3 2025 with a market cap of $3.6B

All Institutions

Institutions: 325
Value Held: $3.6B
Shares Held: 167.6M
Avg Position: $11.0M
Median Position: $748.1K

Hedge Funds

Hedge Funds: 43
Value Held: $1.4B
Shares Held: 66.6M
Avg Position: $33.0M
Median Position: $2.2M

Ownership Breakdown

Institutional (non-HF)

59.91%

$2.2B

Hedge Funds

39.45%

$1.4B

Retail & Other

0.637%

$22.9M

Based on market cap of $3.6B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in ACAD as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	$915.4M 8.48% of portfolio	25.43% 42.9M shares	≤ Q2 2013 Held for 12y 5m+	$10.8B
B BlackRock, Inc. Institution	-	$432.5M 0.01% of portfolio	12.01% 20.3M shares	≤ Q2 2013 Held for 12y 5m+	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$323.9M 0.00% of portfolio	9.00% 15.2M shares	≤ Q2 2013 Held for 12y 5m+	$6.69T
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$154.8M 0.01% of portfolio	4.30% 7.3M shares	≤ Q2 2013 Held for 12y 5m+	$2.88T
RTW INVESTMENTS, LLC Hedge Fund•Sector	Peter M Fong President	$152.5M 1.89% of portfolio	4.23% 7.1M shares	Q2 2022 Held for 3y 5m	$8.1B
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$66.9M 0.00% of portfolio	1.86% 3.1M shares	≤ Q2 2013 Held for 12y 5m+	$1.57T
DIMENSIONAL FUND ADVISORS LP Long Only Manager	David Paul Butler CEO	$59.7M 0.01% of portfolio	1.66% 2.8M shares	Q3 2019 Held for 6y 2m	$466.32B
A ADAGE CAPITAL PARTNERS GP LLC Institution	-	$53.0M 0.08% of portfolio	1.47% 2.5M shares	Q2 2025 Held for 5 months	$63.0B
P Palo Alto Investors, LLC Hedge Fund•Long/Short	Angela Elizabeth Nguyen-Dinh CCO	$52.6M 9.74% of portfolio	1.46% 2.5M shares	Q1 2016 Held for 9y 8m	$540.4M
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	$50.8M 2.05% of portfolio	1.41% 2.4M shares	Q3 2025 Held for 2 months	$2.5B

Net Capital Flow

Institutional buying and selling activity for ACAD in Q3 2025

Traded: +$39.7M
Buyers: 185
Sellers: 133
Total Bought: +$416.6M
Total Sold: −$376.8M
Avg Position: $9.9M

Biggest Buyers

Institution	Net Bought	Current Position
B BRAIDWELL LP Hedge Fund•Multi-Strategy	+$50.8M +2.4M shares	$50.8M 2.4M shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	+$40.1M +1.9M shares	$53.0M 2.5M shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$30.2M +1.4M shares	$31.7M 1.5M shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	+$28.0M +1.3M shares	$35.2M 1.6M shares
STATE STREET CORP Institution	+$23.0M +1.1M shares	$154.8M 7.3M shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Long Only Manager	+$22.5M +1.1M shares	$23.7M 1.1M shares
R ROYAL BANK OF CANADA Institution	+$18.0M +841.9K shares	$19.2M 900.4K shares
$DEUTSCHE BANK AG\ logo$ DEUTSCHE BANK AG\ Institution	+$16.8M +787.6K shares	$32.5M 1.5M shares
GOLDMAN SACHS GROUP INC Institution	+$13.5M +634.0K shares	$44.9M 2.1M shares
Frazier Life Sciences Management, L.P. Venture Capital	+$13.1M +613.8K shares	$13.1M 613.8K shares

Biggest Sellers

Institution	Net Sold	Current Position
MORGAN STANLEY RIA/Wealth	−$62.4M −2.9M shares	$25.4M 1.2M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$57.4M −2.7M shares	$6.9M 323.5K shares
RTW INVESTMENTS, LLC Hedge Fund•Sector	−$39.5M −1.9M shares	$152.5M 7.1M shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$36.0M −1.7M shares	$31.7M 1.5M shares
A AMERICAN CENTURY COMPANIES INC Institution	−$24.5M −1.1M shares	$8.9M 418.3K shares
F FRED ALGER MANAGEMENT INC Long Only Manager	−$17.5M −820.4K shares	$33.4M 1.6M shares
Woodline Partners LP Hedge Fund•Long/Short	−$14.6M −685.7K shares	$3.2M 151.5K shares
FIRST TRUST ADVISORS LP ETF Provider	−$10.5M −491.2K shares	$41.5M 1.9M shares
D D. E. Shaw & Co., Inc. Institution	−$8.6M −403.4K shares	$33.3M 1.6M shares
B BlackRock, Inc. Institution	−$8.2M −383.8K shares	$432.5M 20.3M shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited ACAD in Q3 2025

New Positions: 17
New Value: $8.9M
Exited Positions: 34
Exited Value: $21.1M

New Positions

Institution	Position Value
A Axecap Investments, LLC Institution	$4.3M 203.4K shares
C Colony Group, LLC Institution	$2.1M 19.9K shares
GeoWealth Management, LLC RIA/Wealth	$901.6K 42.3K shares
V Vestcor Investment Management Corp Institution	$482.3K 22.6K shares
CoreCap Advisors, LLC RIA/Wealth	$391.0K 18.3K shares
Quantinno Capital Management LP Hedge Fund•Market Neutral	$239.0K 11.2K shares
CenterBook Partners LP Hedge Fund•Market Neutral	$238.0K 11.2K shares
ISAM Funds Ltd Hedge Fund•Quant	$92.8K 4.3K shares
USA Financial Portformulas Corp Long Only Manager	$40.5K 1.9K shares
S Salomon & Ludwin, LLC Institution	$11.2K 516.0 shares

Exited Positions

Institution	Previous Position
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy	$4.3M 199.0K shares
J J. Goldman & Co LP Hedge Fund•Multi-Strategy	$3.5M 164.3K shares
Exome Asset Management LLC Hedge Fund•Sector	$2.0M 93.2K shares
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy	$2.0M 92.0K shares
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$1.9M 87.8K shares
T TEXAS PERMANENT SCHOOL FUND Institution	$1.6M 72.2K shares
UBS OCONNOR LLC Long Only Manager	$927.5K 43.0K shares
SPRINGBOK CAPITAL MANAGEMENT, LLC Fund of Funds	$593.4K 27.5K shares
W Winton Capital Group Ltd Institution	$543.6K 25.2K shares
National Wealth Management Group, LLC RIA/Wealth	$468.8K 21.7K shares

Options Activity

Institutions with the largest Call and Put options positions in ACAD as of Q3 2025

Call Positions: 14
Call Value: $31.3M
Put Positions: 14
Put Value: $23.6M

Call Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$13.5M 6.3K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$7.4M 3.5K contracts
J J. Goldman & Co LP Hedge Fund•Multi-Strategy	$2.0M 945.0 contracts
GOLDMAN SACHS GROUP INC Institution	$1.9M 898.0 contracts
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$1.9M 890.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.7M 789.0 contracts
N NOMURA HOLDINGS INC Institution	$881.3K 413.0 contracts
Centiva Capital, LP Hedge Fund•Multi-Strategy	$815.2K 382.0 contracts
J JANE STREET GROUP, LLC Institution	$535.6K 251.0 contracts
W WOLVERINE TRADING, LLC Institution	$371.0K 174.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$7.7M 3.6K contracts
Caption Management, LLC Hedge Fund•Long/Short	$3.8M 1.8K contracts
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$3.2M 1.5K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$2.0M 935.0 contracts
GOLDMAN SACHS GROUP INC Institution	$1.9M 898.0 contracts
L LMR Partners LLP Institution	$1.5M 700.0 contracts
J JANE STREET GROUP, LLC Institution	$1.2M 542.0 contracts
W WOLVERINE TRADING, LLC Institution	$722.7K 339.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$512.2K 240.0 contracts
Walleye Trading LLC RIA/Wealth	$433.2K 203.0 contracts

Most Committed Institutions

Institutions with ACAD as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
P Palo Alto Investors, LLC Hedge Fund•Long/Short	Angela Elizabeth Nguyen-Dinh CCO	9.74% $52.6M	1.46% 2.5M shares	Q1 2016 Held for 9y 8m	$540.4M
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	8.48% $915.4M	25.43% 42.9M shares	≤ Q2 2013 Held for 12y 5m+	$10.8B
N Nan Fung Group Holdings Ltd Institution	-	4.05% $2.2M	0.06% 103.0K shares	Q4 2021 Held for 3y 11m	$54.3M
S Stonepine Capital Management, LLC Institution	-	3.03% $3.7M	0.10% 174.5K shares	Q2 2024 Held for 1y 5m	$123.0M
B Birchview Capital, LP Hedge Fund•Value	Matthew William Strobeck CIO	2.80% $3.6M	0.10% 171.0K shares	Q2 2019 Held for 6y 5m	$130.3M
A Axecap Investments, LLC Institution	-	2.68% $4.3M	0.12% 203.4K shares	Q3 2025 Held for 2 months	$161.9M
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	2.05% $50.8M	1.41% 2.4M shares	Q3 2025 Held for 2 months	$2.5B
RTW INVESTMENTS, LLC Hedge Fund•Sector	Peter M Fong President	1.89% $152.5M	4.23% 7.1M shares	Q2 2022 Held for 3y 5m	$8.1B
T TANG CAPITAL MANAGEMENT LLC Institution	-	1.26% $32.0M	0.89% 1.5M shares	Q3 2023 Held for 2y 2m	$2.5B
S SPHERA FUNDS MANAGEMENT LTD. Institution	-	0.76% $3.2M	0.09% 148.9K shares	Q1 2024 Held for 1y 8m	$416.3M

Hedge Fund Spotlight

Discover hedge funds investing in ACAD

Magnetar Financial LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerDavid Jay Snyderman

Portfolio Value: $15.4B
Positions: 724
Last Reported: Q3 2025

Sector Allocation

Position in Acadia Pharmaceuticals

Market Value: $480.9K
Shares Held: 22.5K
Portfolio Weight: 0.00%
Owned Since: 2025-Q3

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