Aprea Therapeutics, Inc.
APRE • NASDAQ
Aprea Therapeutics, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Oren Gilad, with a market cap of $5.8M. As of Q3 2025, 28% of shares are held by 23 institutional investors, with AIGH Capital Management LLC as the largest holder at 9.26%.
Chief Executive OfficerOren Gilad
Overview
Overview of institutional ownership in APRE as of Q3 2025 with a market cap of $8.6M
All Institutions
- Institutions
- 23
- Value Held
- $2.4M
- Shares Held
- 1.6M
- Avg Position
- $103.8K
- Median Position
- $18.1K
Hedge Funds
- Hedge Funds
- 5
- Value Held
- $1.5M
- Shares Held
- 1.0M
- Avg Position
- $296.5K
- Median Position
- $202.3K
Ownership Breakdown
Based on market cap of $8.6M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in APRE as of Q3 2025
| Institution | Position Value |
|---|---|
A AIGH Capital Management LLC Hedge Fund•Long/Short | $795.5K 0.25% of portfolio |
S SPHERA FUNDS MANAGEMENT LTD. Institution | $398.3K 0.10% of portfolio |
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy | $303.5K 0.02% of portfolio |
 VANGUARD GROUP INC Institution | $233.4K 0.00% of portfolio |
D DAFNA Capital Management LLC Hedge Fund•Event Driven | $202.3K 0.05% of portfolio |
 Sio Capital Management, LLC Hedge Fund•Long/Short | $165.5K 0.04% of portfolio |
 MORGAN STANLEY RIA/Wealth | $97.1K 0.00% of portfolio |
 GEODE CAPITAL MANAGEMENT LLC ETF Provider | $65.8K 0.00% of portfolio |
B BNP PARIBAS ARBITRAGE, SA Institution | $25.3K 0.00% of portfolio |
L LPL Financial LLC Institution | $23.7K 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for APRE in Q3 2025
- Traded
- −$293.4K
- Buyers
- 7
- Sellers
- 8
- Total Bought
- +$26.4K
- Total Sold
- −$319.9K
- Avg Position
- $95.5K
Biggest Buyers
| Institution | Net Bought |
|---|---|
H HRT FINANCIAL LLC Institution | +$18.1K +12.3K shares |
MORGAN STANLEY RIA/Wealth | +$3.7K +2.5K shares |
B BNP PARIBAS ARBITRAGE, SA Institution | +$2.5K +1.7K shares |
GEODE CAPITAL MANAGEMENT LLC ETF Provider | +$2.2K +1.5K shares |
 BANK OF AMERICA CORP /DE/ Institution | +$7.4 +5.0 shares |
 CITIGROUP INC Institution | +$7.0 +5.0 shares |
S SBI Securities Co., Ltd. Institution | +$3.0 +2.0 shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
Sio Capital Management, LLC Hedge Fund•Long/Short | −$246.5K −167.1K shares |
 DIMENSIONAL FUND ADVISORS LP Long Only Manager | −$24.6K −14.5K shares |
VANGUARD GROUP INC Institution | −$23.0K −15.6K shares |
 LANDSCAPE CAPITAL MANAGEMENT, L.L.C. Hedge Fund•Market Neutral | −$19.9K −13.5K shares |
T Tower Research Capital LLC Institution | −$3.5K −2.4K shares |
L LPL Financial LLC Institution | −$1.5K −1.0K shares |
 FMR LLC Institution | −$852.0 −501.0 shares |
 UBS Group AG Institution | −$6.7 −5.0 shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited APRE in Q3 2025
- New Positions
- 0
- New Value
- -
- Exited Positions
- 2
- Exited Value
- $25.4K
New Positions
| Institution | Position Value |
|---|---|
| No new positions found | |
Exited Positions
| Institution | Previous Position |
|---|---|
DIMENSIONAL FUND ADVISORS LP Long Only Manager | $24.6K 14.5K shares |
FMR LLC Institution | $852.0 501.0 shares |
Options Activity
Institutions with the largest Call and Put options positions in APRE as of Q3 2025
- Call Positions
- 0
- Call Value
- -
- Put Positions
- 0
- Put Value
- -
Call Positions
| Institution | Position Value |
|---|---|
| No call positions found | |
Put Positions
| Institution | Position Value |
|---|---|
| No put positions found | |
Most Committed Institutions
Institutions with APRE as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
A AIGH Capital Management LLC Hedge Fund•Long/Short | 0.25% $795.5K |
S SPHERA FUNDS MANAGEMENT LTD. Institution | 0.10% $398.3K |
D DAFNA Capital Management LLC Hedge Fund•Event Driven | 0.05% $202.3K |
Sio Capital Management, LLC Hedge Fund•Long/Short | 0.04% $165.5K |
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy | 0.02% $303.5K |
LANDSCAPE CAPITAL MANAGEMENT, L.L.C. Hedge Fund•Market Neutral | 0.00% $15.5K |
 MB, LEVIS & ASSOCIATES, LLC RIA/Wealth | 0.00% $1.2K |
 WealthCollab, LLC RIA/Wealth | 0.00% $234.0 |
H HRT FINANCIAL LLC Institution | 0.00% $18.1K |
G GROUP ONE TRADING, L.P. Institution | 0.00% $851.0 |
Hedge Fund Spotlight
Discover hedge funds investing in APRE
A
AIGH Capital Management LLC
Hedge Fund • Long/Short
Portfolio ManagerOrin Zvi Hirschman
- Portfolio Value
- $317.0M
- Positions
- 35
- Last Reported
- Q3 2025
Sector Allocation
Position in Aprea Therapeutics, Inc.
- Market Value
- $795.5K
- Shares Held
- 539.3K
- Portfolio Weight
- 0.25%
- Owned Since
- 2023-Q1
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Unknown Unknown | $31.4M | 9.91% | |
Unknown Unknown | $31.4M | 9.91% | |
Medical - Diagnostics & Research Healthcare | $25.4M | 8.01% |
