Avalo Therapeutics

AVTX • NASDAQ

Avalo Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by Garry A. Neil, with a market cap of $337.3M. As of Q3 2025, 116% of shares are held by 65 institutional investors, with BVF INC/IL as the largest holder at 10.3%.

Chief Executive OfficerGarry A. Neil

Market Cap$337.3M

Biotechnology

Healthcare

Employees19.0

Websiteavalotx.com

Country

United States of America

Overview

Overview of institutional ownership in AVTX as of Q3 2025 with a market cap of $167.2M

All Institutions

Institutions: 65
Value Held: $194.7M
Shares Held: 15.3M
Avg Position: $3.0M
Median Position: $953.3K

Hedge Funds

Hedge Funds: 26
Value Held: $130.3M
Shares Held: 10.3M
Avg Position: $5.0M
Median Position: $1.9M

Ownership Breakdown

Institutional (non-HF)

38.51%

$64.4M

Hedge Funds

77.96%

$130.3M

Retail & Other

Based on market cap of $167.2M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in AVTX as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BVF INC/IL Institution	-	$17.2M 0.70% of portfolio	10.30% 1.4M shares	Q3 2024 Held for 1y 2m	$2.5B
ORBIMED ADVISORS LLC Hedge Fund•Sector	Sam Block Iii CFO	$17.1M 0.42% of portfolio	10.26% 1.3M shares	Q3 2024 Held for 1y 2m	$4.1B
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	Daniel J. Mack Managing Partner	$15.7M 0.97% of portfolio	9.39% 1.2M shares	Q1 2025 Held for 8 months	$1.6B
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	Steven Alan Cohen CEO	$13.4M 0.03% of portfolio	8.01% 1.1M shares	Q3 2025 Held for 2 months	$43.2B
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	Jonathan Bo-Shing Chu Founder	$12.8M 1.30% of portfolio	7.65% 1.0M shares	Q1 2024 Held for 1y 8m	$983.0M
C Caligan Partners LP Hedge Fund•Activist	Tiffany Crowley CFO	$10.6M 1.47% of portfolio	6.34% 833.3K shares	Q3 2025 Held for 2 months	$720.7M
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dmitry Balyasny CIO	$10.4M 0.02% of portfolio	6.22% 817.4K shares	Q3 2025 Held for 2 months	$48.1B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	$9.2M 1.33% of portfolio	5.48% 720.9K shares	Q3 2025 Held for 2 months	$689.7M
VANGUARD GROUP INC Institution	Salim Ramji CEO	$8.8M 0.00% of portfolio	5.27% 692.6K shares	Q2 2024 Held for 1y 5m	$6.69T
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	$8.4M 0.10% of portfolio	5.04% 663.0K shares	Q3 2024 Held for 1y 2m	$8.1B

Net Capital Flow

Institutional buying and selling activity for AVTX in Q3 2025

Traded: +$95.1M
Buyers: 47
Sellers: 9
Total Bought: +$107.7M
Total Sold: −$12.6M
Avg Position: $2.9M

Biggest Buyers

Institution	Net Bought	Current Position
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$13.4M +1.1M shares	$13.4M 1.1M shares
C Caligan Partners LP Hedge Fund•Activist	+$10.6M +833.3K shares	$10.6M 833.3K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$10.4M +817.4K shares	$10.4M 817.4K shares
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	+$9.2M +720.9K shares	$9.2M 720.9K shares
VANGUARD GROUP INC Institution	+$6.7M +525.7K shares	$8.8M 692.6K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$6.1M +481.7K shares	$6.1M 481.7K shares
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	+$5.1M +398.3K shares	$12.8M 1.0M shares
ORBIMED ADVISORS LLC Hedge Fund•Sector	+$4.9M +382.3K shares	$17.1M 1.3M shares
B BVF INC/IL Institution	+$4.2M +327.2K shares	$17.2M 1.4M shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	+$3.3M +258.8K shares	$3.3M 258.8K shares

Biggest Sellers

Institution	Net Sold	Current Position
Deep Track Capital, LP Hedge Fund•Long/Short	−$5.4M −422.5K shares	$1.8M 144.6K shares
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	−$3.4M −270.0K shares	$8.4M 663.0K shares
Adviser Investments LLC Family Office	−$2.2M −174.5K shares	$1.1M 86.5K shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	−$919.4K −72.3K shares	$411.7K 32.4K shares
UBS Group AG Institution	−$489.5K −38.5K shares	$574.6K 45.2K shares
GEODE CAPITAL MANAGEMENT LLC ETF Provider	−$79.8K −6.3K shares	$1.3M 104.2K shares
NORTHERN TRUST CORP Institution	−$52.1K −4.1K shares	$236.1K 18.6K shares
B BlackRock, Inc. Institution	−$20.9K −1.6K shares	$2.0M 154.3K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	−$5.0 −1.0 shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited AVTX in Q3 2025

New Positions: 18
New Value: $38.9M
Exited Positions: 1
Exited Value: $5.0

New Positions

Institution	Position Value
C Caligan Partners LP Hedge Fund•Activist	$10.6M 833.3K shares
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$9.2M 720.9K shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	$3.3M 258.8K shares
AMERIPRISE FINANCIAL INC Institution	$2.7M 213.6K shares
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short	$2.4M 188.1K shares
Ally Bridge Group LLC Hedge Fund•Sector	$2.3M 178.1K shares
Boxer Capital Management, LLC Hedge Fund•Long/Short	$1.6M 125.0K shares
Exome Asset Management LLC Hedge Fund•Sector	$1.3M 100.0K shares
Patient Square Capital LP Private Equity	$1.3M 100.0K shares
C CANTOR FITZGERALD, L. P. Institution	$1.1M 85.2K shares

Exited Positions

Institution	Previous Position
RAYMOND JAMES FINANCIAL INC RIA/Wealth	$5.0 1.0 shares

Options Activity

Institutions with the largest Call and Put options positions in AVTX as of Q3 2025

Call Positions: 2
Call Value: $1.3M
Put Positions: 3
Put Value: $608.0K

Call Positions

Institution	Position Value
DLD Asset Management, LP Hedge Fund•Multi-Strategy	$673.0K 531.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$644.4K 507.0 contracts

Put Positions

Institution	Position Value
DLD Asset Management, LP Hedge Fund•Multi-Strategy	$296.6K 234.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$172.9K 136.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$138.5K 109.0 contracts

Most Committed Institutions

Institutions with AVTX as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
V Velan Capital Investment Management LP Institution	-	3.15% $3.4M	2.00% 263.6K shares	Q4 2024 Held for 11 months	$106.5M
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short	Guo Ting Managing Partner	2.36% $2.4M	1.43% 188.1K shares	Q3 2025 Held for 2 months	$101.5M
Ally Bridge Group LLC Hedge Fund•Sector	Slanix Paul T Alex President	1.90% $2.3M	1.35% 178.1K shares	Q3 2025 Held for 2 months	$119.4M
C Caligan Partners LP Hedge Fund•Activist	Tiffany Crowley CFO	1.47% $10.6M	6.34% 833.3K shares	Q3 2025 Held for 2 months	$720.7M
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	1.33% $9.2M	5.48% 720.9K shares	Q3 2025 Held for 2 months	$689.7M
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	Jonathan Bo-Shing Chu Founder	1.30% $12.8M	7.65% 1.0M shares	Q1 2024 Held for 1y 8m	$983.0M
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	Daniel J. Mack Managing Partner	0.97% $15.7M	9.39% 1.2M shares	Q1 2025 Held for 8 months	$1.6B
Exome Asset Management LLC Hedge Fund•Sector	Alex R Forschner President	0.86% $1.3M	0.76% 100.0K shares	Q3 2025 Held for 2 months	$148.0M
B BVF INC/IL Institution	-	0.70% $17.2M	10.30% 1.4M shares	Q3 2024 Held for 1y 2m	$2.5B
Boxer Capital Management, LLC Hedge Fund•Long/Short	Aaron Isaac Davis CEO	0.52% $1.6M	0.95% 125.0K shares	Q3 2025 Held for 2 months	$303.5M

Hedge Fund Spotlight

Discover hedge funds investing in AVTX

Ally Bridge Group LLC

Hedge Fund • Sector

Portfolio ManagerSlanix Paul T Alex

Portfolio Value: $119.4M
Positions: 18
Last Reported: Q3 2025

Sector Allocation

Position in Avalo Therapeutics

Market Value: $2.3M
Shares Held: 178.1K
Portfolio Weight: 1.90%
Owned Since: 2025-Q3

Top Holding	Sector	Market Value	Weight
1 Soleno Therapeutics SLNO	Biotechnology Healthcare	$20.4M	17.12%
2 Madrigal Pharmaceuticals, Inc. MDGL	Biotechnology Healthcare	$15.0M	12.54%
3 Atai Life Sciences ATAI	Biotechnology Healthcare	$12.1M	10.13%