Compass Therapeutics, Inc.

CMPX • NASDAQ

Compass Therapeutics, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Thomas Schuetz, MD, PhD, with a market cap of $917.8M. As of Q3 2025, 88% of shares are held by 122 institutional investors, with TANG CAPITAL MANAGEMENT LLC as the largest holder at 9.8%.

President of Research and DevelopmentThomas Schuetz, MD, PhD

Market Cap$917.8M

Biotechnology

Healthcare

Employees32.0

Websitecompasstherapeutics.com

Country

United States of America

Overview

Overview of institutional ownership in CMPX as of Q3 2025 with a market cap of $600.5M

All Institutions

Institutions: 122
Value Held: $528.7M
Shares Held: 151.0M
Avg Position: $4.3M
Median Position: $181.5K

Hedge Funds

Hedge Funds: 20
Value Held: $182.9M
Shares Held: 52.3M
Avg Position: $9.1M
Median Position: $3.2M

Ownership Breakdown

Institutional (non-HF)

57.58%

$345.7M

Hedge Funds

30.46%

$182.9M

Retail & Other

11.97%

$71.9M

Based on market cap of $600.5M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in CMPX as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
T TANG CAPITAL MANAGEMENT LLC Institution	-	$58.8M 2.32% of portfolio	9.80% 16.8M shares	Q3 2024 Held for 1y 2m	$2.5B
ORBIMED ADVISORS LLC Hedge Fund•Sector	Sam Block Iii CFO	$53.3M 1.29% of portfolio	8.87% 15.2M shares	Q4 2021 Held for 3y 11m	$4.1B
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	$49.4M 1.50% of portfolio	8.22% 14.1M shares	Q2 2025 Held for 5 months	$3.3B
Blackstone Group L.P. Institution	Jonathan D. Gray President	$34.4M 0.15% of portfolio	5.74% 9.8M shares	Q4 2021 Held for 3y 11m	$23.2B
Vivo Capital, LLC Venture Capital	Jack Bech Nielsen Managing Partner	$33.4M 2.69% of portfolio	5.56% 9.5M shares	Q4 2021 Held for 3y 11m	$1.2B
E Enavate Sciences GP, LLC Institution	-	$27.3M 8.32% of portfolio	4.54% 7.8M shares	Q4 2024 Held for 11 months	$327.5M
B BlackRock, Inc. Institution	-	$25.8M 0.00% of portfolio	4.30% 7.4M shares	Q2 2022 Held for 3y 5m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$24.7M 0.00% of portfolio	4.12% 7.1M shares	Q4 2021 Held for 3y 11m	$6.69T
A ADAGE CAPITAL PARTNERS GP LLC Institution	-	$18.2M 0.03% of portfolio	3.02% 5.2M shares	Q4 2021 Held for 3y 11m	$63.0B
MPM Oncology Impact Management LP Institution	Christian Albrecht Wulf Von Schimmelmann Managing Partner	$17.8M 2.91% of portfolio	2.96% 5.1M shares	Q1 2024 Held for 1y 8m	$610.9M

Net Capital Flow

Institutional buying and selling activity for CMPX in Q3 2025

Traded: +$150.0M
Buyers: 73
Sellers: 40
Total Bought: +$160.1M
Total Sold: −$10.1M
Avg Position: $4.0M

Biggest Buyers

Institution	Net Bought	Current Position
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	+$24.3M +7.0M shares	$49.4M 14.1M shares
B BVF INC/IL Institution	+$16.6M +4.8M shares	$16.6M 4.8M shares
Vivo Capital, LLC Venture Capital	+$12.3M +3.5M shares	$33.4M 9.5M shares
T TANG CAPITAL MANAGEMENT LLC Institution	+$11.6M +3.3M shares	$58.8M 16.8M shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$9.9M +2.8M shares	$9.9M 2.8M shares
RTW INVESTMENTS, LLC Hedge Fund•Sector	+$8.8M +2.5M shares	$8.8M 2.5M shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$8.4M +2.4M shares	$11.3M 3.2M shares
VANGUARD GROUP INC Institution	+$7.7M +2.2M shares	$24.7M 7.1M shares
Logos Global Management LP Hedge Fund•Long/Short	+$7.2M +2.1M shares	$7.2M 2.1M shares
S Sofinnova Ventures Inc Venture Capital	+$7.1M +2.0M shares	$7.1M 2.0M shares

Biggest Sellers

Institution	Net Sold	Current Position
Caption Management, LLC Hedge Fund•Long/Short	−$2.0M −571.3K shares	$539.6K 154.2K shares
MPM Oncology Impact Management LP Institution	−$1.9M −546.5K shares	$17.8M 5.1M shares
Rock Springs Capital Management LP Hedge Fund•Sector	−$1.7M −488.3K shares	$15.7M 4.5M shares
S SG Americas Securities, LLC Institution	−$781.8K −223.4K shares	$522.6K 149.3K shares
Blackstone Group L.P. Institution	−$647.7K −185.0K shares	$34.4M 9.8M shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	−$509.6K −145.6K shares	$276.5K 79.0K shares
JPMORGAN CHASE & CO Institution	−$442.5K −126.4K shares	$7.0M 2.0M shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	−$375.6K −107.3K shares	$69.9K 20.0K shares
UBS Group AG Institution	−$228.4K −65.3K shares	$693.9K 198.3K shares
MORGAN STANLEY RIA/Wealth	−$216.3K −61.8K shares	$654.3K 187.0K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited CMPX in Q3 2025

New Positions: 22
New Value: $46.2M
Exited Positions: 9
Exited Value: $381.1K

New Positions

Institution	Position Value
B BVF INC/IL Institution	$16.6M 4.8M shares
RTW INVESTMENTS, LLC Hedge Fund•Sector	$8.8M 2.5M shares
Logos Global Management LP Hedge Fund•Long/Short	$7.2M 2.1M shares
S Sofinnova Ventures Inc Venture Capital	$7.1M 2.0M shares
L Longwood Capital Partners LLC Institution	$2.9M 840.1K shares
Burkehill Global Management, LP Hedge Fund•Event Driven	$2.5M 700.0K shares
Atom Investors LP Hedge Fund•Market Neutral	$373.4K 106.7K shares
R Rafferty Asset Management, LLC Institution	$248.4K 71.0K shares
Q Quadrature Capital Ltd Institution	$166.0K 47.4K shares
B Brevan Howard Capital Management LP Institution	$160.6K 45.9K shares

Exited Positions

Institution	Previous Position
H HRT FINANCIAL LLC Institution	$158.0K 60.8K shares
A AMERICAN CENTURY COMPANIES INC Institution	$71.8K 27.6K shares
S STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM Institution	$46.1K 17.7K shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	$41.9K 16.1K shares
PANAGORA ASSET MANAGEMENT INC Hedge Fund•Quant	$41.2K 15.8K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	$12.7K 4.9K shares
VSM Wealth Advisory, LLC RIA/Wealth	$7.8K 3.0K shares
Briaud Financial Planning, Inc RIA/Wealth	$1.0K 700.0 shares
S Skopos Labs, Inc. RIA/Wealth	$614.0 236.0 shares

Options Activity

Institutions with the largest Call and Put options positions in CMPX as of Q3 2025

Call Positions: 3
Call Value: $3.6M
Put Positions: 2
Put Value: -

Call Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$3.5M 10.0K contracts
J JANE STREET GROUP, LLC Institution	$44.8K 128.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$38.5K 110.0 contracts

Put Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	- - contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	- - contracts

Most Committed Institutions

Institutions with CMPX as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
E Enavate Sciences GP, LLC Institution	-	8.32% $27.3M	4.54% 7.8M shares	Q4 2024 Held for 11 months	$327.5M
L Longwood Capital Partners LLC Institution	-	3.04% $2.9M	0.49% 840.1K shares	Q3 2025 Held for 2 months	$96.8M
MPM Oncology Impact Management LP Institution	Christian Albrecht Wulf Von Schimmelmann Managing Partner	2.91% $17.8M	2.96% 5.1M shares	Q1 2024 Held for 1y 8m	$610.9M
B Blue Owl Capital Holdings LP Institution	-	2.85% $9.1M	1.51% 2.6M shares	Q4 2023 Held for 1y 11m	$318.8M
Vivo Capital, LLC Venture Capital	Jack Bech Nielsen Managing Partner	2.69% $33.4M	5.56% 9.5M shares	Q4 2021 Held for 3y 11m	$1.2B
Monashee Investment Management LLC Hedge Fund•Sector	Thomas Joseph Wynn Managing Partner	2.35% $4.4M	0.73% 1.3M shares	Q4 2021 Held for 3y 11m	$186.0M
B Birchview Capital, LP Hedge Fund•Value	Matthew William Strobeck CIO	2.35% $3.1M	0.51% 872.9K shares	Q1 2025 Held for 8 months	$130.3M
T TANG CAPITAL MANAGEMENT LLC Institution	-	2.32% $58.8M	9.80% 16.8M shares	Q3 2024 Held for 1y 2m	$2.5B
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	1.50% $49.4M	8.22% 14.1M shares	Q2 2025 Held for 5 months	$3.3B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	1.44% $9.9M	1.65% 2.8M shares	Q1 2025 Held for 8 months	$689.7M

Hedge Fund Spotlight

Discover hedge funds investing in CMPX

CITADEL ADVISORS LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerKenneth Cordele Griffin

Portfolio Value: $122.08B
Positions: 5,531
Last Reported: Q3 2025

Sector Allocation

Position in Compass Therapeutics, Inc.

Market Value: $816.4K
Shares Held: 233.3K
Portfolio Weight: 0.00%
Owned Since: 2023-Q4

Top Holding	Sector	Market Value	Weight
1 Microsoft MSFT	Software - Infrastructure Technology	$2.1B	1.68%
2 Nvidia NVDA	Semiconductors Technology	$1.8B	1.50%
3 Meta Platforms, Inc. META	Internet Content & Information Communication Services	$1.4B	1.18%