Ensysce Biosciences, Inc.
ENSC • NASDAQ
Ensysce Biosciences, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Dr. Lynn Kirkpatrick, with a market cap of $5.2M. As of Q3 2025, 12% of shares are held by 16 institutional investors, with PERCEPTIVE ADVISORS LLC as the largest holder at 2.92%.
Chief Executive OfficerDr. Lynn Kirkpatrick
Overview
Overview of institutional ownership in ENSC as of Q3 2025 with a market cap of $7.0M
All Institutions
- Institutions
- 16
- Value Held
- $826.4K
- Shares Held
- 348.7K
- Avg Position
- $51.7K
- Median Position
- $28.4K
Hedge Funds
- Hedge Funds
- 3
- Value Held
- $276.7K
- Shares Held
- 116.8K
- Avg Position
- $92.2K
- Median Position
- $36.9K
Ownership Breakdown
Based on market cap of $7.0M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in ENSC as of Q3 2025
| Institution | Position Value |
|---|---|
 PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short | $205.4K 0.01% of portfolio |
A ADAGE CAPITAL PARTNERS GP LLC Institution | $177.1K 0.00% of portfolio |
D DRW Securities, LLC Institution | $163.9K 0.01% of portfolio |
 VANGUARD GROUP INC Institution | $87.0K 0.00% of portfolio |
 RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | $36.9K 0.00% of portfolio |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $34.4K 0.00% of portfolio |
V Virtu Financial LLC Institution | $33.7K 0.00% of portfolio |
 GEODE CAPITAL MANAGEMENT LLC ETF Provider | $30.9K 0.00% of portfolio |
X XTX Topco Ltd Institution | $26.0K 0.00% of portfolio |
 TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC RIA/Wealth | $24.9K 0.02% of portfolio |
Net Capital Flow
Institutional buying and selling activity for ENSC in Q3 2025
- Traded
- +$409.0K
- Buyers
- 11
- Sellers
- 4
- Total Bought
- +$414.6K
- Total Sold
- −$5.6K
- Avg Position
- $45.9K
Biggest Buyers
| Institution | Net Bought |
|---|---|
D DRW Securities, LLC Institution | +$163.9K +69.1K shares |
VANGUARD GROUP INC Institution | +$87.0K +36.7K shares |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | +$36.9K +15.6K shares |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | +$34.4K +14.5K shares |
V Virtu Financial LLC Institution | +$33.7K +14.2K shares |
X XTX Topco Ltd Institution | +$26.0K +11.0K shares |
TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC RIA/Wealth | +$24.9K +10.5K shares |
GEODE CAPITAL MANAGEMENT LLC ETF Provider | +$6.8K +2.9K shares |
 UBS Group AG Institution | +$1.1K +446.0 shares |
 GENWORTH FINANCIAL WEALTH MANAGEMENT, INC Long Only Manager | +$31.0 +13.0 shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
S SBI Securities Co., Ltd. Institution | −$4.5K −1.9K shares |
 MORGAN STANLEY RIA/Wealth | −$843.0 −378.0 shares |
 RAYMOND JAMES FINANCIAL INC RIA/Wealth | −$210.0 −94.0 shares |
T Tower Research Capital LLC Institution | −$49.8 −21.0 shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited ENSC in Q3 2025
- New Positions
- 3
- New Value
- $188.8K
- Exited Positions
- 2
- Exited Value
- $1.1K
New Positions
| Institution | Position Value |
|---|---|
D DRW Securities, LLC Institution | $163.9K 69.1K shares |
TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC RIA/Wealth | $24.9K 10.5K shares |
GENWORTH FINANCIAL WEALTH MANAGEMENT, INC Long Only Manager | $31.0 13.0 shares |
Exited Positions
| Institution | Previous Position |
|---|---|
MORGAN STANLEY RIA/Wealth | $843.0 378.0 shares |
RAYMOND JAMES FINANCIAL INC RIA/Wealth | $210.0 94.0 shares |
Options Activity
Institutions with the largest Call and Put options positions in ENSC as of Q3 2025
- Call Positions
- 0
- Call Value
- -
- Put Positions
- 0
- Put Value
- -
Call Positions
| Institution | Position Value |
|---|---|
| No call positions found | |
Put Positions
| Institution | Position Value |
|---|---|
| No put positions found | |
Most Committed Institutions
Institutions with ENSC as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC RIA/Wealth | 0.02% $24.9K |
D DRW Securities, LLC Institution | 0.01% $163.9K |
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short | 0.01% $205.4K |
V Virtu Financial LLC Institution | 0.00% $33.7K |
X XTX Topco Ltd Institution | 0.00% $26.0K |
A ADAGE CAPITAL PARTNERS GP LLC Institution | 0.00% $177.1K |
T Tower Research Capital LLC Institution | 0.00% $3.2K |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | 0.00% $36.9K |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | 0.00% $34.4K |
S SBI Securities Co., Ltd. Institution | 0.00% $991.0 |
Hedge Fund Spotlight
Discover hedge funds investing in ENSC
PERCEPTIVE ADVISORS LLC
Hedge Fund • Long/Short
Portfolio ManagerJoseph Eric Edelman
- Portfolio Value
- $3.5B
- Positions
- 90
- Last Reported
- Q3 2025
Sector Allocation
Position in Ensysce Biosciences, Inc.
- Market Value
- $205.4K
- Shares Held
- 86.7K
- Portfolio Weight
- 0.01%
- Owned Since
- 2024-Q4
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Biotechnology Healthcare | $288.4M | 8.35% | |
Unknown Unknown | $216.4M | 6.27% | |
Biotechnology Healthcare | $202.7M | 5.87% |
