Fractyl Health

GUTS • NASDAQ

Fractyl Health is a biotechnology company in the healthcare sector on NASDAQ, with a market cap of $307.0M. As of Q3 2025, 69% of shares are held by 72 institutional investors, with Nantahala Capital Management, LLC as the largest holder at 9.18%.

Market Cap$307.0M

Biotechnology

Healthcare

Employees94.0

Websitefractyl.com

Country

United States of America

Overview

Overview of institutional ownership in GUTS as of Q3 2025 with a market cap of $210.2M

All Institutions

Institutions: 72
Value Held: $145.4M
Shares Held: 91.5M
Avg Position: $2.0M
Median Position: $242.2K

Hedge Funds

Hedge Funds: 20
Value Held: $88.2M
Shares Held: 55.5M
Avg Position: $4.4M
Median Position: $2.8M

Ownership Breakdown

Institutional (non-HF)

27.21%

$57.2M

Hedge Funds

41.98%

$88.2M

Retail & Other

30.8%

$64.7M

Based on market cap of $210.2M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in GUTS as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	Daniel J. Mack Managing Partner	$19.3M 1.19% of portfolio	9.18% 12.1M shares	Q3 2025 Held for 2 months	$1.6B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	$16.9M 2.44% of portfolio	8.02% 10.6M shares	Q1 2024 Held for 1y 8m	$689.7M
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy	Anand Christopher Parekh CEO	$9.0M 0.03% of portfolio	4.27% 5.6M shares	Q3 2025 Held for 2 months	$33.0B
Woodline Partners LP Hedge Fund•Long/Short	Karl Heinz Kroeker CIO	$8.8M 0.04% of portfolio	4.17% 5.5M shares	Q1 2024 Held for 1y 8m	$21.3B
Catalio Capital Management, LP Venture Capital	Olga Eduardovna Maltseva COO	$8.3M 1.53% of portfolio	3.94% 5.2M shares	Q4 2024 Held for 11 months	$540.9M
R Rosalind Advisors, Inc. Institution	-	$8.0M 3.02% of portfolio	3.78% 5.0M shares	Q3 2025 Held for 2 months	$263.6M
General Catalyst Group Management, LLC Venture Capital	Hemant Nmn Taneja Managing Partner	$7.8M 0.26% of portfolio	3.69% 4.9M shares	Q2 2025 Held for 5 months	$3.0B
Deer Management Co. LLC Venture Capital	Adam Ralph Fisher Managing Partner	$7.6M 0.68% of portfolio	3.61% 4.8M shares	Q1 2024 Held for 1y 8m	$1.1B
H HCC Manager LLC Institution	-	$7.4M 100.00% of portfolio	3.54% 4.7M shares	Q1 2024 Held for 1y 8m	$7.4M
6 683 Capital Management, LLC Hedge Fund•Long/Short	Ari Jonathan Zweiman Managing Partner	$7.4M 0.70% of portfolio	3.52% 4.7M shares	Q1 2024 Held for 1y 8m	$1.1B

Net Capital Flow

Institutional buying and selling activity for GUTS in Q3 2025

Traded: +$101.4M
Buyers: 48
Sellers: 29
Total Bought: +$102.6M
Total Sold: −$1.2M
Avg Position: $1.6M

Biggest Buyers

Institution	Net Bought	Current Position
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	+$19.3M +12.1M shares	$19.3M 12.1M shares
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	+$16.5M +10.4M shares	$16.9M 10.6M shares
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy	+$9.0M +5.6M shares	$9.0M 5.6M shares
R Rosalind Advisors, Inc. Institution	+$8.0M +5.0M shares	$8.0M 5.0M shares
Catalio Capital Management, LP Venture Capital	+$7.9M +5.0M shares	$8.3M 5.2M shares
Woodline Partners LP Hedge Fund•Long/Short	+$7.8M +4.9M shares	$8.8M 5.5M shares
6 683 Capital Management, LLC Hedge Fund•Long/Short	+$6.4M +4.0M shares	$7.4M 4.7M shares
Soleus Capital Management, L.P. Hedge Fund•Long/Short	+$4.0M +2.5M shares	$4.0M 2.5M shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$3.5M +2.2M shares	$3.5M 2.2M shares
Ikarian Capital, LLC Hedge Fund•Event Driven	+$2.9M +1.8M shares	$2.9M 1.8M shares

Biggest Sellers

Institution	Net Sold	Current Position
B BlackRock, Inc. Institution	−$201.5K −126.7K shares	$1.2M 760.0K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$183.3K −115.3K shares	$648.2K 407.7K shares
Y Y-Intercept Ltd Institution	−$180.5K −111.4K shares	Sold Off 0 shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	−$147.0K −90.8K shares	Sold Off 0 shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$104.8K −64.7K shares	Sold Off 0 shares
Q Qube Research & Technologies Ltd Institution	−$90.1K −56.6K shares	$36.4K 22.9K shares
Jain Global LLC Hedge Fund•Multi-Strategy	−$53.3K −32.9K shares	Sold Off 0 shares
J JANE STREET GROUP, LLC Institution	−$31.1K −19.2K shares	Sold Off 0 shares
C Catalyst Funds Management Pty Ltd Institution	−$25.6K −15.8K shares	Sold Off 0 shares
C Cubist Systematic Strategies, LLC Institution	−$24.5K −15.1K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited GUTS in Q3 2025

New Positions: 22
New Value: $42.3M
Exited Positions: 17
Exited Value: $646.3K

New Positions

Institution	Position Value
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	$19.3M 12.1M shares
R Rosalind Advisors, Inc. Institution	$8.0M 5.0M shares
Soleus Capital Management, L.P. Hedge Fund•Long/Short	$4.0M 2.5M shares
Ikarian Capital, LLC Hedge Fund•Event Driven	$2.9M 1.8M shares
Marshall Wace LLP Institution	$2.8M 1.8M shares
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$1.0M 655.2K shares
C CM Management, LLC Institution	$954.0K 600.0K shares
Logos Global Management LP Hedge Fund•Long/Short	$795.0K 500.0K shares
Burkehill Global Management, LP Hedge Fund•Event Driven	$795.0K 500.0K shares
D D. E. Shaw & Co., Inc. Institution	$467.9K 294.3K shares

Exited Positions

Institution	Previous Position
Y Y-Intercept Ltd Institution	$180.5K 111.4K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$147.0K 90.8K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	$104.8K 64.7K shares
Jain Global LLC Hedge Fund•Multi-Strategy	$53.3K 32.9K shares
J JANE STREET GROUP, LLC Institution	$31.1K 19.2K shares
C Catalyst Funds Management Pty Ltd Institution	$25.6K 15.8K shares
C Cubist Systematic Strategies, LLC Institution	$24.5K 15.1K shares
Hudson Bay Capital Management LP Hedge Fund•Multi-Strategy	$20.2K 12.5K shares
R Russell Investments Group, Ltd. RIA/Wealth	$19.8K 12.2K shares
FMR LLC Institution	$18.8K 11.6K shares

Options Activity

Institutions with the largest Call and Put options positions in GUTS as of Q3 2025

Call Positions: 0
Call Value: -
Put Positions: 0
Put Value: -

Call Positions

Institution	Position Value
No call positions found

Put Positions

Institution	Position Value
No put positions found

Most Committed Institutions

Institutions with GUTS as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
H HCC Manager LLC Institution	-	100.00% $7.4M	3.54% 4.7M shares	Q1 2024 Held for 1y 8m	$7.4M
M28 Capital Management LP Hedge Fund•Long/Short	Christopher Michael Taliercio President	4.34% $3.0M	1.40% 1.9M shares	Q1 2024 Held for 1y 8m	$68.0M
R Rosalind Advisors, Inc. Institution	-	3.02% $8.0M	3.78% 5.0M shares	Q3 2025 Held for 2 months	$263.6M
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	2.44% $16.9M	8.02% 10.6M shares	Q1 2024 Held for 1y 8m	$689.7M
Catalio Capital Management, LP Venture Capital	Olga Eduardovna Maltseva COO	1.53% $8.3M	3.94% 5.2M shares	Q4 2024 Held for 11 months	$540.9M
N Nantahala Capital Management, LLC Hedge Fund•Multi-Strategy	Daniel J. Mack Managing Partner	1.19% $19.3M	9.18% 12.1M shares	Q3 2025 Held for 2 months	$1.6B
C CM Management, LLC Institution	-	0.80% $954.0K	0.45% 600.0K shares	Q3 2025 Held for 2 months	$119.9M
6 683 Capital Management, LLC Hedge Fund•Long/Short	Ari Jonathan Zweiman Managing Partner	0.70% $7.4M	3.52% 4.7M shares	Q1 2024 Held for 1y 8m	$1.1B
Deer Management Co. LLC Venture Capital	Adam Ralph Fisher Managing Partner	0.68% $7.6M	3.61% 4.8M shares	Q1 2024 Held for 1y 8m	$1.1B
Ikarian Capital, LLC Hedge Fund•Event Driven	Neil Tristan Shahrestani CEO	0.58% $2.9M	1.36% 1.8M shares	Q3 2025 Held for 2 months	$494.3M

Hedge Fund Spotlight

Discover hedge funds investing in GUTS

683 Capital Management, LLC

Hedge Fund • Long/Short

Portfolio ManagerAri Jonathan Zweiman

Portfolio Value: $1.1B
Positions: 109
Last Reported: Q3 2025

Sector Allocation

Position in Fractyl Health

Market Value: $7.4M
Shares Held: 4.7M
Portfolio Weight: 0.70%
Owned Since: 2024-Q1

Top Holding	Sector	Market Value	Weight
1 Capital One Financial COF	Financial - Credit Services Financial Services	$69.1M	6.52%
2 uniQure QURE	Biotechnology Healthcare	$62.5M	5.89%
3 Carvana CVNA	Specialty Retail Consumer Cyclical	$56.6M	5.34%