IO Biotech
IOBT • NASDAQ
IO Biotech is a biotechnology company in the healthcare sector on NASDAQ, led by Mai-Britt Zocca, with a market cap of $58.1M. As of Q3 2025, 15% of shares are held by 21 institutional investors, with Novo A/S as the largest holder at 3.81%.
Chief Executive OfficerMai-Britt Zocca
Market Cap$58.1M
Biotechnology
Healthcare
Employees68.0
Websiteiobiotech.com
Country
United States of America
Overview
Overview of institutional ownership in IOBT as of Q3 2025 with a market cap of $23.9M
All Institutions
- Institutions
- 21
- Value Held
- $3.6M
- Shares Held
- 9.9M
- Avg Position
- $170.9K
- Median Position
- $30.3K
Hedge Funds
- Hedge Funds
- 4
- Value Held
- $1.3M
- Shares Held
- 3.7M
- Avg Position
- $337.3K
- Median Position
- $352.2K
Ownership Breakdown
Based on market cap of $23.9M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in IOBT as of Q3 2025
| Institution | Position Value |
|---|---|
N Novo A/S Institution | $912.3K 0.06% of portfolio |
 Ikarian Capital, LLC Hedge Fund•Event Driven | $554.1K 0.11% of portfolio |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $505.6K 0.00% of portfolio |
 Marshall Wace LLP Institution | $378.9K 0.00% of portfolio |
 BANK OF AMERICA CORP /DE/ Institution | $290.4K 0.00% of portfolio |
 MORGAN STANLEY RIA/Wealth | $242.7K 0.00% of portfolio |
 BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | $214.7K 0.01% of portfolio |
 RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | $198.7K 0.00% of portfolio |
 Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | $90.8K 0.00% of portfolio |
X XTX Topco Ltd Institution | $65.1K 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for IOBT in Q3 2025
- Traded
- −$13.4M
- Buyers
- 14
- Sellers
- 18
- Total Bought
- +$1.7M
- Total Sold
- −$15.0M
- Avg Position
- $105.6K
Biggest Buyers
| Institution | Net Bought |
|---|---|
Ikarian Capital, LLC Hedge Fund•Event Driven | +$554.1K +1.5M shares |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | +$505.6K +1.4M shares |
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | +$214.7K +591.2K shares |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | +$148.2K +408.0K shares |
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | +$90.8K +250.0K shares |
X XTX Topco Ltd Institution | +$54.5K +150.0K shares |
Q Quadrature Capital Ltd Institution | +$30.3K +83.4K shares |
 GOLDMAN SACHS GROUP INC Institution | +$24.2K +66.6K shares |
V Virtu Financial LLC Institution | +$14.2K +39.1K shares |
 Hilton Capital Management, LLC Long Only Manager | +$9.3K +25.5K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 Vivo Capital, LLC Venture Capital | −$8.6M −6.2M shares |
 Partner Fund Management, L.P. Hedge Fund•Sector | −$2.7M −2.0M shares |
−$1.2M −864.2K shares | |
 LANDSCAPE CAPITAL MANAGEMENT, L.L.C. Hedge Fund•Market Neutral | −$482.9K −347.4K shares |
D Dauntless Investment Group, LLC Institution | −$450.9K −324.4K shares |
Marshall Wace LLP Institution | −$378.9K −1.1M shares |
N Novo A/S Institution | −$305.7K −842.0K shares |
BANK OF AMERICA CORP /DE/ Institution | −$295.9K −815.1K shares |
 Soleus Capital Management, L.P. Hedge Fund•Long/Short | −$267.8K −192.7K shares |
 SECTORAL ASSET MANAGEMENT INC Venture Capital | −$163.6K −117.7K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited IOBT in Q3 2025
- New Positions
- 5
- New Value
- $832.4K
- Exited Positions
- 13
- Exited Value
- $14.0M
New Positions
| Institution | Position Value |
|---|---|
Ikarian Capital, LLC Hedge Fund•Event Driven | $554.1K 1.5M shares |
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | $214.7K 591.2K shares |
Q Quadrature Capital Ltd Institution | $30.3K 83.4K shares |
GOLDMAN SACHS GROUP INC Institution | $24.2K 66.6K shares |
Hilton Capital Management, LLC Long Only Manager | $9.3K 25.5K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
Vivo Capital, LLC Venture Capital | $8.6M 6.2M shares |
Partner Fund Management, L.P. Hedge Fund•Sector | $2.7M 2.0M shares |
$1.2M 864.2K shares | |
LANDSCAPE CAPITAL MANAGEMENT, L.L.C. Hedge Fund•Market Neutral | $482.9K 347.4K shares |
D Dauntless Investment Group, LLC Institution | $450.9K 324.4K shares |
Soleus Capital Management, L.P. Hedge Fund•Long/Short | $267.8K 192.7K shares |
SECTORAL ASSET MANAGEMENT INC Venture Capital | $163.6K 117.7K shares |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $40.1K 28.9K shares |
J JANE STREET GROUP, LLC Institution | $36.1K 25.9K shares |
 ACADIAN ASSET MANAGEMENT LLC Long Only Manager | $32.5K 23.4K shares |
Options Activity
Institutions with the largest Call and Put options positions in IOBT as of Q3 2025
- Call Positions
- 0
- Call Value
- -
- Put Positions
- 0
- Put Value
- -
Call Positions
| Institution | Position Value |
|---|---|
| No call positions found | |
Put Positions
| Institution | Position Value |
|---|---|
| No put positions found | |
Most Committed Institutions
Institutions with IOBT as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
Ikarian Capital, LLC Hedge Fund•Event Driven | 0.11% $554.1K |
N Novo A/S Institution | 0.06% $912.3K |
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | 0.01% $214.7K |
X XTX Topco Ltd Institution | 0.00% $65.1K |
P PKS Advisory Services, LLC RIA/Wealth | 0.00% $7.1K |
V Virtu Financial LLC Institution | 0.00% $14.2K |
Hilton Capital Management, LLC Long Only Manager | 0.00% $9.3K |
B BRIDGEWAY CAPITAL MANAGEMENT INC Long Only Manager | 0.00% $27.2K |
Marshall Wace LLP Institution | 0.00% $378.9K |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | 0.00% $505.6K |
Hedge Fund Spotlight
Discover hedge funds investing in IOBT
Ikarian Capital, LLC
Hedge Fund • Event Driven
Portfolio ManagerNeil Tristan Shahrestani
- Portfolio Value
- $494.3M
- Positions
- 116
- Last Reported
- Q3 2025
Sector Allocation
Position in IO Biotech
- Market Value
- $554.1K
- Shares Held
- 1.5M
- Portfolio Weight
- 0.11%
- Owned Since
- 2025-Q3
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Unknown Unknown | $53.0M | 10.73% | |
Unknown Unknown | $33.4M | 6.76% | |
Biotechnology Healthcare | $27.2M | 5.49% |
