Mirum Pharmaceuticals, Inc.

MIRM • NASDAQ

Mirum Pharmaceuticals, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Christopher Peetz, with a market cap of $3.4B. As of Q3 2025, 113% of shares are held by 266 institutional investors, with Frazier Life Sciences Management, L.P. as the largest holder at 13.53%.

Chief Executive OfficerChristopher Peetz

Market Cap$3.4B

Biotechnology

Healthcare

Employees278.0

Websitemirumpharma.com

Country

United States of America

Overview

Overview of institutional ownership in MIRM as of Q3 2025 with a market cap of $3.7B

All Institutions

Institutions: 266
Value Held: $4.2B
Shares Held: 57.1M
Avg Position: $15.7M
Median Position: $1.0M

Hedge Funds

Hedge Funds: 46
Value Held: $610.0M
Shares Held: 8.3M
Avg Position: $13.3M
Median Position: $3.1M

Ownership Breakdown

Institutional (non-HF)

96.9%

$3.6B

Hedge Funds

16.56%

$610.0M

Retail & Other

Based on market cap of $3.7B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in MIRM as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
Frazier Life Sciences Management, L.P. Venture Capital	James Newman Topper Managing Partner	$498.2M 14.93% of portfolio	13.53% 6.8M shares	Q1 2022 Held for 3y 8m	$3.3B
HENDERSON GROUP PLC Institution	Ali Dibadj CEO	$366.5M 0.17% of portfolio	9.95% 5.0M shares	Q1 2023 Held for 2y 8m	$218.74B
B BlackRock, Inc. Institution	-	$264.1M 0.00% of portfolio	7.17% 3.6M shares	Q3 2019 Held for 6y 2m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$186.6M 0.00% of portfolio	5.07% 2.5M shares	Q3 2019 Held for 6y 2m	$6.69T
E EVENTIDE ASSET MANAGEMENT, LLC Long Only Manager	Robin Cheriakalath John CEO	$184.9M 3.04% of portfolio	5.02% 2.5M shares	Q3 2022 Held for 3y 2m	$6.1B
B BVF INC/IL Institution	-	$109.6M 4.44% of portfolio	2.98% 1.5M shares	Q3 2023 Held for 2y 2m	$2.5B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$98.7M 0.00% of portfolio	2.68% 1.3M shares	Q3 2019 Held for 6y 2m	$2.88T
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	Robert W Sharps President	$94.1M 0.01% of portfolio	2.55% 1.3M shares	Q3 2022 Held for 3y 2m	$912.31B
N Novo A/S Institution	-	$92.7M 6.08% of portfolio	2.52% 1.3M shares	Q3 2019 Held for 6y 2m	$1.5B
T TANG CAPITAL MANAGEMENT LLC Institution	-	$90.6M 3.57% of portfolio	2.46% 1.2M shares	Q2 2022 Held for 3y 5m	$2.5B

Net Capital Flow

Institutional buying and selling activity for MIRM in Q3 2025

Traded: +$141.5M
Buyers: 161
Sellers: 93
Total Bought: +$522.0M
Total Sold: −$380.5M
Avg Position: $14.8M

Biggest Buyers

Institution	Net Bought	Current Position
WELLINGTON MANAGEMENT CO LLP Long Only Manager	+$49.3M +672.1K shares	$58.0M 790.7K shares
FMR LLC Institution	+$42.6M +580.8K shares	$46.9M 640.2K shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	+$39.3M +536.7K shares	$44.9M 612.3K shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$39.0M +531.8K shares	$58.0M 790.7K shares
VOLORIDGE INVESTMENT MANAGEMENT, LLC Hedge Fund•Multi-Strategy	+$27.3M +372.0K shares	$28.6M 389.6K shares
D D. E. Shaw & Co., Inc. Institution	+$27.0M +368.6K shares	$67.7M 923.5K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$23.3M +317.2K shares	$23.3M 317.2K shares
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC Long Only Manager	+$23.0M +313.3K shares	$23.0M 313.3K shares
TimesSquare Capital Management, LLC Long Only Manager	+$22.0M +300.6K shares	$22.0M 300.6K shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	+$18.7M +254.5K shares	$36.5M 497.5K shares

Biggest Sellers

Institution	Net Sold	Current Position
B BVF INC/IL Institution	−$92.8M −1.3M shares	$109.6M 1.5M shares
JPMORGAN CHASE & CO Institution	−$27.9M −380.1K shares	$7.3M 100.2K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$26.8M −365.8K shares	$76.3M 1.0M shares
A AXA Institution	−$17.9M −351.7K shares	Sold Off 0 shares
HENDERSON GROUP PLC Institution	−$17.5M −238.7K shares	$366.5M 5.0M shares
N Novo A/S Institution	−$17.3M −236.0K shares	$92.7M 1.3M shares
Eversept Partners, LLC Hedge Fund•Long/Short	−$13.4M −182.9K shares	$3.6M 49.3K shares
WELLS FARGO & COMPANY/MN Institution	−$12.5M −171.1K shares	$2.0M 27.1K shares
Pictet Asset Management Holding SA Long Only Manager	−$11.7M −159.9K shares	$39.7M 541.3K shares
Polar Capital Holdings Plc Long Only Manager	−$11.3M −154.4K shares	$60.2M 820.6K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited MIRM in Q3 2025

New Positions: 41
New Value: $44.4M
Exited Positions: 16
Exited Value: $36.3M

New Positions

Institution	Position Value
TimesSquare Capital Management, LLC Long Only Manager	$22.0M 300.6K shares
Voleon Capital Management LP Hedge Fund•Quant	$6.3M 86.5K shares
G GCIC Ltd. Institution	$5.6M 75.8K shares
T TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY Institution	$1.1M 14.7K shares
WOLVERINE ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$782.2K 10.7K shares
O OMERS ADMINISTRATION Corp Institution	$740.4K 10.1K shares
CAPSTONE INVESTMENT ADVISORS, LLC Hedge Fund•Multi-Strategy	$733.4K 10.0K shares
DIMENSIONAL FUND ADVISORS LP Long Only Manager	$514.5K 7.0K shares
B Baader Bank INC Institution	$502.8K 6.9K shares
B Bryce Point Capital, LLC Hedge Fund•Market Neutral	$463.2K 6.3K shares

Exited Positions

Institution	Previous Position
A AXA Institution	$17.9M 351.7K shares
Prosight Management, LP Hedge Fund•Long/Short	$10.2M 200.0K shares
Phocas Financial Corp. Long Only Manager	$1.8M 35.6K shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	$1.7M 34.2K shares
Affinity Asset Advisors, LLC Hedge Fund•Long/Short	$1.3M 24.7K shares
Verition Fund Management LLC Hedge Fund•Multi-Strategy	$1.1M 22.6K shares
UBS OCONNOR LLC Long Only Manager	$1.1M 21.4K shares
O OPTIONS SOLUTIONS, LLC Hedge Fund•Sector	$485.0K 9.5K shares
A AXQ CAPITAL, LP Hedge Fund•Market Neutral	$289.8K 5.7K shares
H HSBC HOLDINGS PLC Institution	$272.3K 5.3K shares

Options Activity

Institutions with the largest Call and Put options positions in MIRM as of Q3 2025

Call Positions: 5
Call Value: $6.3M
Put Positions: 3
Put Value: $7.7M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$2.8M 386.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$953.0K 130.0 contracts
N NOMURA HOLDINGS INC Institution	$923.7K 126.0 contracts
Caption Management, LLC Hedge Fund•Long/Short	$865.1K 118.0 contracts
J JANE STREET GROUP, LLC Institution	$740.4K 101.0 contracts

Put Positions

Institution	Position Value
J JANE STREET GROUP, LLC Institution	$5.7M 784.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.5M 208.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$439.9K 60.0 contracts

Most Committed Institutions

Institutions with MIRM as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Frazier Life Sciences Management, L.P. Venture Capital	James Newman Topper Managing Partner	14.93% $498.2M	13.53% 6.8M shares	Q1 2022 Held for 3y 8m	$3.3B
BOONE CAPITAL MANAGEMENT LLC Hedge Fund•Long/Short	Daniel Walter Boone President	12.88% $39.3M	1.07% 535.7K shares	Q3 2023 Held for 2y 2m	$305.0M
F First Turn Management, LLC Hedge Fund•Long/Short	Lisa Gable Wheatley Managing Partner	6.28% $41.8M	1.14% 570.6K shares	Q4 2023 Held for 1y 11m	$666.0M
N Novo A/S Institution	-	6.08% $92.7M	2.52% 1.3M shares	Q3 2019 Held for 6y 2m	$1.5B
B BVF INC/IL Institution	-	4.44% $109.6M	2.98% 1.5M shares	Q3 2023 Held for 2y 2m	$2.5B
T TANG CAPITAL MANAGEMENT LLC Institution	-	3.57% $90.6M	2.46% 1.2M shares	Q2 2022 Held for 3y 5m	$2.5B
Rock Springs Capital Management LP Hedge Fund•Sector	Nnamdi C Etoh CFO	3.27% $55.8M	1.52% 761.1K shares	Q3 2019 Held for 6y 2m	$1.7B
H Highlander Partners, L.P. Institution	-	3.14% $9.0M	0.24% 123.0K shares	Q4 2021 Held for 3y 11m	$286.7M
E EVENTIDE ASSET MANAGEMENT, LLC Long Only Manager	Robin Cheriakalath John CEO	3.04% $184.9M	5.02% 2.5M shares	Q3 2022 Held for 3y 2m	$6.1B
H HealthInvest Partners AB Institution	-	2.85% $728.5K	0.19% 93.6K shares	Q1 2024 Held for 1y 8m	$25.6M

Hedge Fund Spotlight

Discover hedge funds investing in MIRM

Trexquant Investment LP

Hedge Fund • Quant

Portfolio ManagerTaesoon (Tyger) Park

Portfolio Value: $9.7B
Positions: 1,540
Last Reported: Q3 2025

Sector Allocation

Position in Mirum Pharmaceuticals, Inc.

Market Value: $8.1M
Shares Held: 110.0K
Portfolio Weight: 0.08%
Owned Since: 2025-Q2

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