PepGen

PEPG • NASDAQ

PepGen is a biotechnology company in the healthcare sector on NASDAQ, led by James McArthur, with a market cap of $389.1M. As of Q3 2025, 83% of shares are held by 72 institutional investors, with RA CAPITAL MANAGEMENT, LLC as the largest holder at 29.19%.

President and Chief Executive OfficerJames McArthur

Market Cap$389.1M

Biotechnology

Healthcare

Employees65.0

Websitepepgen.com

Country

United States of America

Overview

Overview of institutional ownership in PEPG as of Q3 2025 with a market cap of $317.6M

All Institutions

Institutions: 72
Value Held: $262.1M
Shares Held: 56.7M
Avg Position: $3.6M
Median Position: $743.0K

Hedge Funds

Hedge Funds: 31
Value Held: $196.6M
Shares Held: 42.6M
Avg Position: $6.3M
Median Position: $2.3M

Ownership Breakdown

Institutional (non-HF)

20.62%

$65.5M

Hedge Funds

61.91%

$196.6M

Retail & Other

17.47%

$55.5M

Based on market cap of $317.6M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in PEPG as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	$92.7M 1.15% of portfolio	29.19% 20.1M shares	Q2 2022 Held for 3y 5m	$8.1B
VIKING GLOBAL INVESTORS LP Hedge Fund•Long/Short	Ole Andreas Halvorsen CEO	$16.1M 0.04% of portfolio	5.07% 3.5M shares	Q2 2022 Held for 3y 5m	$38.5B
COMMODORE CAPITAL LP Hedge Fund•Long/Short	Michael Jonathan Kramarz Managing Partner	$10.9M 0.53% of portfolio	3.43% 2.4M shares	Q3 2025 Held for 2 months	$2.0B
Vivo Capital, LLC Venture Capital	Jack Bech Nielsen Managing Partner	$10.7M 0.86% of portfolio	3.38% 2.3M shares	Q3 2025 Held for 2 months	$1.2B
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	Steven Alan Cohen CEO	$9.4M 0.02% of portfolio	2.95% 2.0M shares	Q1 2025 Held for 8 months	$43.2B
B BVF INC/IL Institution	-	$8.8M 0.36% of portfolio	2.79% 1.9M shares	Q3 2025 Held for 2 months	$2.5B
Laurion Capital Management LP Hedge Fund•Multi-Strategy	Masih Mohebbi-Forushani CFO	$8.7M 1.29% of portfolio	2.75% 1.9M shares	Q2 2022 Held for 3y 5m	$679.7M
VANGUARD GROUP INC Institution	Salim Ramji CEO	$8.2M 0.00% of portfolio	2.57% 1.8M shares	Q2 2022 Held for 3y 5m	$6.69T
HENDERSON GROUP PLC Institution	Ali Dibadj CEO	$6.9M 0.00% of portfolio	2.18% 1.5M shares	Q3 2025 Held for 2 months	$218.74B
RTW INVESTMENTS, LLC Hedge Fund•Sector	Peter M Fong President	$6.9M 0.09% of portfolio	2.18% 1.5M shares	Q3 2025 Held for 2 months	$8.1B

Net Capital Flow

Institutional buying and selling activity for PEPG in Q3 2025

Traded: +$157.6M
Buyers: 51
Sellers: 31
Total Bought: +$168.6M
Total Sold: −$11.0M
Avg Position: $3.1M

Biggest Buyers

Institution	Net Bought	Current Position
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	+$43.3M +9.4M shares	$92.7M 20.1M shares
COMMODORE CAPITAL LP Hedge Fund•Long/Short	+$10.9M +2.4M shares	$10.9M 2.4M shares
Vivo Capital, LLC Venture Capital	+$10.7M +2.3M shares	$10.7M 2.3M shares
VIKING GLOBAL INVESTORS LP Hedge Fund•Long/Short	+$9.2M +2.0M shares	$16.1M 3.5M shares
B BVF INC/IL Institution	+$8.8M +1.9M shares	$8.8M 1.9M shares
HENDERSON GROUP PLC Institution	+$6.9M +1.5M shares	$6.9M 1.5M shares
RTW INVESTMENTS, LLC Hedge Fund•Sector	+$6.9M +1.5M shares	$6.9M 1.5M shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$6.2M +1.3M shares	$6.2M 1.3M shares
Deep Track Capital, LP Hedge Fund•Long/Short	+$5.5M +1.2M shares	$5.5M 1.2M shares
TCG Crossover Management, LLC Venture Capital	+$5.5M +1.2M shares	$5.5M 1.2M shares

Biggest Sellers

Institution	Net Sold	Current Position
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$4.7M −1.0M shares	$2.3M 500.3K shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$3.4M −729.2K shares	$9.4M 2.0M shares
B BlackRock, Inc. Institution	−$914.3K −197.9K shares	$2.1M 450.1K shares
O Opaleye Management Inc. Hedge Fund•Long/Short	−$762.3K −165.0K shares	$346.5K 75.0K shares
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	−$333.0K −300.0K shares	Sold Off 0 shares
Prosight Management, LP Hedge Fund•Long/Short	−$270.8K −244.0K shares	Sold Off 0 shares
B BRIDGEWAY CAPITAL MANAGEMENT INC Long Only Manager	−$133.6K −28.9K shares	$291.1K 63.0K shares
Q Qube Research & Technologies Ltd Institution	−$81.0K −73.0K shares	Sold Off 0 shares
GOLDMAN SACHS GROUP INC Institution	−$78.4K −70.6K shares	Sold Off 0 shares
Marshall Wace LLP Institution	−$43.5K −39.2K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited PEPG in Q3 2025

New Positions: 24
New Value: $71.8M
Exited Positions: 13
Exited Value: $908.0K

New Positions

Institution	Position Value
COMMODORE CAPITAL LP Hedge Fund•Long/Short	$10.9M 2.4M shares
Vivo Capital, LLC Venture Capital	$10.7M 2.3M shares
B BVF INC/IL Institution	$8.8M 1.9M shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$6.2M 1.3M shares
TCG Crossover Management, LLC Venture Capital	$5.5M 1.2M shares
Deep Track Capital, LP Hedge Fund•Long/Short	$5.5M 1.2M shares
A AWM Investment Company, Inc. Hedge Fund•Event Driven	$4.7M 1.0M shares
EcoR1 Capital, LLC Hedge Fund•Sector	$3.7M 800.0K shares
Logos Global Management LP Hedge Fund•Long/Short	$3.5M 750.0K shares
S Siren, L.L.C. Institution	$3.2M 700.0K shares

Exited Positions

Institution	Previous Position
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$333.0K 300.0K shares
Prosight Management, LP Hedge Fund•Long/Short	$270.8K 244.0K shares
Q Qube Research & Technologies Ltd Institution	$81.0K 73.0K shares
GOLDMAN SACHS GROUP INC Institution	$78.4K 70.6K shares
Marshall Wace LLP Institution	$43.5K 39.2K shares
ZACKS INVESTMENT MANAGEMENT RIA/Wealth	$42.2K 38.0K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	$36.3K 32.7K shares
JustInvest LLC Long Only Manager	$17.7K 15.9K shares
G GROUP ONE TRADING, L.P. Institution	$4.5K 4.0K shares
WELLS FARGO & COMPANY/MN Institution	$363.0 327.0 shares

Options Activity

Institutions with the largest Call and Put options positions in PEPG as of Q3 2025

Call Positions: 3
Call Value: $5.2M
Put Positions: 2
Put Value: $474.0K

Call Positions

Institution	Position Value
J JANE STREET GROUP, LLC Institution	$5.0M 10.9K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$100.7K 218.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$98.9K 214.0 contracts

Put Positions

Institution	Position Value
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$389.9K 844.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$84.1K 182.0 contracts

Most Committed Institutions

Institutions with PEPG as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Laurion Capital Management LP Hedge Fund•Multi-Strategy	Masih Mohebbi-Forushani CFO	1.29% $8.7M	2.75% 1.9M shares	Q2 2022 Held for 3y 5m	$679.7M
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Michael Saulnier CFO	1.15% $92.7M	29.19% 20.1M shares	Q2 2022 Held for 3y 5m	$8.1B
Vivo Capital, LLC Venture Capital	Jack Bech Nielsen Managing Partner	0.86% $10.7M	3.38% 2.3M shares	Q3 2025 Held for 2 months	$1.2B
Monashee Investment Management LLC Hedge Fund•Sector	Thomas Joseph Wynn Managing Partner	0.74% $1.4M	0.44% 300.0K shares	Q3 2025 Held for 2 months	$186.0M
COMMODORE CAPITAL LP Hedge Fund•Long/Short	Michael Jonathan Kramarz Managing Partner	0.53% $10.9M	3.43% 2.4M shares	Q3 2025 Held for 2 months	$2.0B
Octagon Capital Advisors LP Hedge Fund•Sector	Ting (Nmn) Jia Founder	0.51% $3.2M	1.02% 700.0K shares	Q3 2025 Held for 2 months	$637.4M
Ikarian Capital, LLC Hedge Fund•Event Driven	Neil Tristan Shahrestani CEO	0.50% $2.5M	0.78% 536.0K shares	Q1 2025 Held for 8 months	$494.3M
A AWM Investment Company, Inc. Hedge Fund•Event Driven	David Michael Greenhouse President	0.44% $4.7M	1.49% 1.0M shares	Q3 2025 Held for 2 months	$1.1B
Boxer Capital Management, LLC Hedge Fund•Long/Short	Aaron Isaac Davis CEO	0.38% $1.2M	0.36% 250.0K shares	Q3 2025 Held for 2 months	$303.5M
M MONIMUS CAPITAL MANAGEMENT, LP Hedge Fund•Long/Short	Brian Jeffrey Bellinger Managing Partner	0.37% $484.2K	0.15% 104.8K shares	Q3 2025 Held for 2 months	$130.6M

Hedge Fund Spotlight

Discover hedge funds investing in PEPG

VIKING GLOBAL INVESTORS LP

Hedge Fund • Long/Short

Portfolio ManagerOle Andreas Halvorsen

Portfolio Value: $38.5B
Positions: 77
Last Reported: Q3 2025

Sector Allocation

Position in PepGen

Market Value: $16.1M
Shares Held: 3.5M
Portfolio Weight: 0.04%
Owned Since: 2022-Q2

Top Holding	Sector	Market Value	Weight
1 PNC Financial Services PNC	Banks - Regional Financial Services	$1.6B	4.16%
2 JPMorgan Chase JPM	Banks - Diversified Financial Services	$1.6B	4.15%
3 Charles Schwab Corporation SCHW	Financial - Capital Markets Financial Services	$1.6B	4.12%