Replimune Group

REPL • NASDAQ

Replimune Group is a biotechnology company in the healthcare sector on NASDAQ, led by Dr. Sushil Patel, with a market cap of $798.6M. As of Q3 2025, 106% of shares are held by 161 institutional investors, with BAKER BROS. ADVISORS LP as the largest holder at 14.15%.

Chief Executive OfficerDr. Sushil Patel

Market Cap$798.6M

Biotechnology

Healthcare

Employees331.0

Websitereplimune.com

Country

United States of America

Overview

Overview of institutional ownership in REPL as of Q3 2025 with a market cap of $327.1M

All Institutions

Institutions: 161
Value Held: $347.5M
Shares Held: 82.9M
Avg Position: $2.2M
Median Position: $112.1K

Hedge Funds

Hedge Funds: 29
Value Held: $149.7M
Shares Held: 35.7M
Avg Position: $5.2M
Median Position: $503.8K

Ownership Breakdown

Institutional (non-HF)

60.49%

$197.8M

Hedge Funds

45.77%

$149.7M

Retail & Other

Based on market cap of $327.1M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in REPL as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	$46.3M 0.43% of portfolio	14.15% 11.0M shares	Q2 2020 Held for 5y 5m	$10.8B
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	Robert W Sharps President	$34.8M 0.00% of portfolio	10.64% 8.3M shares	Q2 2020 Held for 5y 5m	$912.31B
RTW INVESTMENTS, LLC Hedge Fund•Sector	Peter M Fong President	$26.8M 0.33% of portfolio	8.19% 6.4M shares	Q2 2024 Held for 1y 5m	$8.1B
B BlackRock, Inc. Institution	-	$24.2M 0.00% of portfolio	7.40% 5.8M shares	Q3 2018 Held for 7y 2m	$5.67T
FCPM III SERVICES B.V. Real Assets	Andrew David Lindner Managing Partner	$17.4M 3.48% of portfolio	5.33% 4.2M shares	Q4 2023 Held for 1y 11m	$500.4M
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	Steven Alan Cohen CEO	$15.2M 0.04% of portfolio	4.65% 3.6M shares	Q4 2024 Held for 11 months	$43.2B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$14.6M 0.00% of portfolio	4.46% 3.5M shares	Q3 2018 Held for 7y 2m	$6.69T
T TANG CAPITAL MANAGEMENT LLC Institution	-	$14.2M 0.56% of portfolio	4.36% 3.4M shares	Q2 2024 Held for 1y 5m	$2.5B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$12.3M 0.00% of portfolio	3.75% 2.9M shares	Q3 2018 Held for 7y 2m	$2.88T
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	$11.5M 0.47% of portfolio	3.52% 2.8M shares	Q2 2024 Held for 1y 5m	$2.5B

Net Capital Flow

Institutional buying and selling activity for REPL in Q3 2025

Traded: −$49.3M
Buyers: 99
Sellers: 95
Total Bought: +$107.4M
Total Sold: −$156.7M
Avg Position: $1.6M

Biggest Buyers

Institution	Net Bought	Current Position
RTW INVESTMENTS, LLC Hedge Fund•Sector	+$18.1M +4.3M shares	$26.8M 6.4M shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$12.2M +2.9M shares	$15.2M 3.6M shares
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy	+$10.2M +2.4M shares	$11.0M 2.6M shares
B BRAIDWELL LP Hedge Fund•Multi-Strategy	+$9.8M +2.3M shares	$11.5M 2.8M shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$9.2M +2.2M shares	$11.0M 2.6M shares
E Erste Asset Management GmbH Institution	+$7.0M +1.6M shares	$7.1M 1.6M shares
TORONTO DOMINION BANK Institution	+$5.7M +1.4M shares	$5.7M 1.4M shares
FMR LLC Institution	+$4.1M +969.4K shares	$5.7M 1.4M shares
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	+$4.1M +968.5K shares	$4.1M 978.9K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$3.3M +795.7K shares	$6.7M 1.6M shares

Biggest Sellers

Institution	Net Sold	Current Position
Marshall Wace LLP Institution	−$17.3M −1.9M shares	Sold Off 0 shares
R Redmile Group, LLC Hedge Fund•Sector	−$17.3M −4.1M shares	$2.2M 535.8K shares
S Sofinnova Ventures Inc Venture Capital	−$16.8M −1.8M shares	Sold Off 0 shares
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	−$10.5M −2.5M shares	$34.8M 8.3M shares
MPM Oncology Impact Management LP Institution	−$9.1M −983.8K shares	Sold Off 0 shares
R Rosalind Advisors, Inc. Institution	−$8.4M −900.0K shares	Sold Off 0 shares
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	−$8.3M −896.7K shares	Sold Off 0 shares
EcoR1 Capital, LLC Hedge Fund•Sector	−$7.9M −850.3K shares	Sold Off 0 shares
Omega Fund Management Inc. Venture Capital	−$7.2M −1.7M shares	$1.0M 248.7K shares
Ally Bridge Group LLC Hedge Fund•Sector	−$4.9M −528.5K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited REPL in Q3 2025

New Positions: 21
New Value: $9.7M
Exited Positions: 49
Exited Value: $106.1M

New Positions

Institution	Position Value
TORONTO DOMINION BANK Institution	$5.7M 1.4M shares
Quinn Opportunity Partners LLC Hedge Fund•Event Driven	$2.7M 650.7K shares
Eversept Partners, LLC Hedge Fund•Long/Short	$251.4K 60.0K shares
V Virtu Financial LLC Institution	$250.1K 59.7K shares
Diametric Capital, LP Hedge Fund•Long/Short	$209.5K 50.0K shares
Scientech Research LLC Hedge Fund•Market Neutral	$102.4K 24.4K shares
Ballentine Partners, LLC Family Office	$91.9K 21.9K shares
G GRIFFIN ASSET MANAGEMENT, INC. Institution	$82.0K 19.6K shares
HighTower Advisors, LLC RIA/Wealth	$67.6K 16.1K shares
W WOLVERINE TRADING, LLC Institution	$66.4K 15.3K shares

Exited Positions

Institution	Previous Position
Marshall Wace LLP Institution	$17.3M 1.9M shares
S Sofinnova Ventures Inc Venture Capital	$16.8M 1.8M shares
MPM Oncology Impact Management LP Institution	$9.1M 983.8K shares
R Rosalind Advisors, Inc. Institution	$8.4M 900.0K shares
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	$8.3M 896.7K shares
EcoR1 Capital, LLC Hedge Fund•Sector	$7.9M 850.3K shares
Ally Bridge Group LLC Hedge Fund•Sector	$4.9M 528.5K shares
Artisan Partners Limited Partnership Long Only Manager	$4.8M 511.4K shares
Catalio Capital Management, LP Venture Capital	$3.1M 330.3K shares
E Ensign Peak Advisors, Inc Institution	$3.0M 322.4K shares

Options Activity

Institutions with the largest Call and Put options positions in REPL as of Q3 2025

Call Positions: 20
Call Value: $37.2M
Put Positions: 13
Put Value: $9.5M

Call Positions

Institution	Position Value
Ally Bridge Group LLC Hedge Fund•Sector	$15.1M 36.0K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$7.5M 18.0K contracts
Caption Management, LLC Hedge Fund•Long/Short	$3.6M 8.5K contracts
DIADEMA PARTNERS LP Hedge Fund•Long/Short	$2.6M 6.1K contracts
J JANE STREET GROUP, LLC Institution	$1.4M 3.4K contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	$1.3M 3.0K contracts
DLD Asset Management, LP Hedge Fund•Multi-Strategy	$1.2M 2.9K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.1M 2.6K contracts
Centiva Capital, LP Hedge Fund•Multi-Strategy	$1.0M 2.5K contracts
DeepCurrents Investment Group LLC Hedge Fund•Multi-Strategy	$839.7K 20.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$7.2M 17.3K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.6M 3.9K contracts
J JANE STREET GROUP, LLC Institution	$352.0K 840.0 contracts
DLD Asset Management, LP Hedge Fund•Multi-Strategy	$167.6K 400.0 contracts
S Squarepoint Ops LLC Hedge Fund•Quant	$70.4K 168.0 contracts
W WOLVERINE TRADING, LLC Institution	$60.8K 140.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$11.7K 28.0 contracts
Walleye Trading LLC RIA/Wealth	$5.9K 14.0 contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	- - contracts
S Sofinnova Ventures Inc Venture Capital	- - contracts

Most Committed Institutions

Institutions with REPL as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
FCPM III SERVICES B.V. Real Assets	Andrew David Lindner Managing Partner	3.48% $17.4M	5.33% 4.2M shares	Q4 2023 Held for 1y 11m	$500.4M
Boxer Capital Management, LLC Hedge Fund•Long/Short	Aaron Isaac Davis CEO	1.45% $4.4M	1.35% 1.1M shares	Q4 2024 Held for 11 months	$303.5M
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy	David Barnett Grossman Managing Partner	1.10% $11.0M	3.36% 2.6M shares	Q2 2025 Held for 5 months	$1.0B
T TANG CAPITAL MANAGEMENT LLC Institution	-	0.56% $14.2M	4.36% 3.4M shares	Q2 2024 Held for 1y 5m	$2.5B
N Nan Fung Group Holdings Ltd Institution	-	0.49% $267.0K	0.08% 63.7K shares	Q1 2022 Held for 3y 8m	$54.3M
Omega Fund Management Inc. Venture Capital	Alexandra Rankel Pearsall CFO	0.47% $1.0M	0.32% 248.7K shares	Q3 2018 Held for 7y 2m	$222.4M
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	0.47% $11.5M	3.52% 2.8M shares	Q2 2024 Held for 1y 5m	$2.5B
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	0.43% $46.3M	14.15% 11.0M shares	Q2 2020 Held for 5y 5m	$10.8B
A ADAR1 Capital Management, LLC Hedge Fund•Long/Short	Daniel Pawel Schneeberger Managing Partner	0.41% $4.1M	1.25% 978.9K shares	Q2 2025 Held for 5 months	$993.7M
RTW INVESTMENTS, LLC Hedge Fund•Sector	Peter M Fong President	0.33% $26.8M	8.19% 6.4M shares	Q2 2024 Held for 1y 5m	$8.1B

Hedge Fund Spotlight

Discover hedge funds investing in REPL

Walleye Trading Advisors, LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerWilliam Dunning England

Portfolio Value: $11.2B
Positions: 1,691
Last Reported: Q3 2025

Sector Allocation

Position in Replimune Group

Market Value: $88.2K
Shares Held: 21.1K
Portfolio Weight: 0.00%
Owned Since: 2025-Q3

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