89bio, Inc.
ETNB • NASDAQ
89bio, Inc. is a biotechnology company in the healthcare sector on NASDAQ, led by Rohan Palekar, with a market cap of $2.2B. As of Q3 2025, 104% of shares are held by 194 institutional investors, with RA CAPITAL MANAGEMENT, LLC as the largest holder at 13.39%.
CEORohan Palekar
Overview
Overview of institutional ownership in ETNB as of Q3 2025 with a market cap of $2.2B
All Institutions
- Institutions
- 194
- Value Held
- $2.3B
- Shares Held
- 154.6M
- Avg Position
- $11.7M
- Median Position
- $1.2M
Hedge Funds
- Hedge Funds
- 41
- Value Held
- $1.1B
- Shares Held
- 72.4M
- Avg Position
- $25.9M
- Median Position
- $4.0M
Ownership Breakdown
Based on market cap of $2.2B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in ETNB as of Q3 2025
| Institution | Position Value |
|---|---|
 RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | $292.4M 3.63% of portfolio |
 Pentwater Capital Management LP Hedge Fund•Event Driven | $172.7M 1.64% of portfolio |
B BlackRock, Inc. Institution | $151.7M 0.00% of portfolio |
 Deep Track Capital, LP Hedge Fund•Long/Short | $137.5M 3.91% of portfolio |
A ADAGE CAPITAL PARTNERS GP LLC Institution | $133.7M 0.21% of portfolio |
 SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | $121.7M 3.69% of portfolio |
 VANGUARD GROUP INC Institution | $118.4M 0.00% of portfolio |
 venBio Select Advisor LLC RIA/Wealth | $93.9M 1.21% of portfolio |
 GLAZER CAPITAL, LLC Hedge Fund•Multi-Strategy | $82.9M 3.76% of portfolio |
 HENDERSON GROUP PLC Institution | $79.1M 0.04% of portfolio |
Net Capital Flow
Institutional buying and selling activity for ETNB in Q3 2025
- Traded
- +$123.2M
- Buyers
- 116
- Sellers
- 99
- Total Bought
- +$779.7M
- Total Sold
- −$656.5M
- Avg Position
- $9.7M
Biggest Buyers
| Institution | Net Bought |
|---|---|
Pentwater Capital Management LP Hedge Fund•Event Driven | +$172.7M +11.8M shares |
A ADAGE CAPITAL PARTNERS GP LLC Institution | +$104.8M +7.1M shares |
GLAZER CAPITAL, LLC Hedge Fund•Multi-Strategy | +$82.9M +5.6M shares |
 DEUTSCHE BANK AG\ Institution | +$50.2M +3.4M shares |
S SYQUANT CAPITAL SAS Institution | +$38.1M +2.6M shares |
O Omni Event Management Ltd Institution | +$34.5M +2.4M shares |
 TIG Advisors, LLC Hedge Fund•Multi-Strategy | +$32.1M +2.2M shares |
 Hudson Bay Capital Management LP Hedge Fund•Multi-Strategy | +$28.6M +1.9M shares |
 BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | +$21.4M +1.5M shares |
 Weiss Asset Management LP Hedge Fund•Multi-Strategy | +$20.6M +1.4M shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
HENDERSON GROUP PLC Institution | −$226.5M −15.4M shares |
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | −$87.2M −5.9M shares |
 Holocene Advisors, LP Hedge Fund•Long/Short | −$30.1M −3.1M shares |
A Assenagon Asset Management S.A. Institution | −$28.3M −1.9M shares |
 MORGAN STANLEY RIA/Wealth | −$25.6M −1.7M shares |
 Polar Capital Holdings Plc Long Only Manager | −$24.3M −2.5M shares |
 Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | −$22.3M −2.3M shares |
 SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | −$20.0M −2.0M shares |
 RTW INVESTMENTS, LLC Hedge Fund•Sector | −$19.3M −2.0M shares |
 EMERALD ADVISERS INC/PA Long Only Manager | −$19.2M −1.3M shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited ETNB in Q3 2025
- New Positions
- 37
- New Value
- $286.4M
- Exited Positions
- 41
- Exited Value
- $190.5M
New Positions
| Institution | Position Value |
|---|---|
GLAZER CAPITAL, LLC Hedge Fund•Multi-Strategy | $82.9M 5.6M shares |
S SYQUANT CAPITAL SAS Institution | $38.1M 2.6M shares |
O Omni Event Management Ltd Institution | $34.5M 2.4M shares |
TIG Advisors, LLC Hedge Fund•Multi-Strategy | $32.1M 2.2M shares |
Weiss Asset Management LP Hedge Fund•Multi-Strategy | $20.6M 1.4M shares |
C CREDIT INDUSTRIEL ET COMMERCIAL Institution | $8.8M 600.0K shares |
O OMERS ADMINISTRATION Corp Institution | $8.5M 575.1K shares |
 ALPINE ASSOCIATES MANAGEMENT INC. Hedge Fund•Merger Arb | $7.8M 529.8K shares |
 GABELLI FUNDS LLC Long Only Manager | $6.4M 434.0K shares |
 GABELLI SECURITIES INC Hedge Fund•Multi-Strategy | $6.1M 417.9K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
Holocene Advisors, LP Hedge Fund•Long/Short | $30.1M 3.1M shares |
Polar Capital Holdings Plc Long Only Manager | $24.3M 2.5M shares |
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | $22.3M 2.3M shares |
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | $20.0M 2.0M shares |
RTW INVESTMENTS, LLC Hedge Fund•Sector | $19.3M 2.0M shares |
 University of Wisconsin Foundation RIA/Wealth | $11.3M 1.2M shares |
 Integral Health Asset Management, LLC Hedge Fund•Sector | $10.3M 1.1M shares |
R READYSTATE ASSET MANAGEMENT LP Hedge Fund•Multi-Strategy | $8.9M 902.1K shares |
 Candriam Luxembourg S.C.A. Long Only Manager | $7.5M 766.2K shares |
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy | $5.7M 577.0K shares |
Options Activity
Institutions with the largest Call and Put options positions in ETNB as of Q3 2025
- Call Positions
- 15
- Call Value
- $11.4M
- Put Positions
- 21
- Put Value
- $95.3M
Call Positions
| Institution | Position Value |
|---|---|
P PEAK6 LLC Institution | $2.8M 1.9K contracts |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $2.2M 1.5K contracts |
N NOMURA HOLDINGS INC Institution | $1.6M 1.1K contracts |
 Verition Fund Management LLC Hedge Fund•Multi-Strategy | $1.4M 968.0 contracts |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $1.2M 813.0 contracts |
E EQUITEC PROPRIETARY MARKETS, LLC Institution | $937.9K 638.0 contracts |
C CSS LLC/IL Institution | $470.4K 320.0 contracts |
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | $424.8K 289.0 contracts |
 Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy | $183.8K 125.0 contracts |
 Walleye Trading LLC RIA/Wealth | $86.7K 59.0 contracts |
Put Positions
| Institution | Position Value |
|---|---|
L LMR Partners LLP Institution | $26.5M 18.0K contracts |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $24.4M 16.6K contracts |
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | $16.1M 10.9K contracts |
C CSS LLC/IL Institution | $5.2M 3.6K contracts |
 UBS Group AG Institution | $5.1M 3.4K contracts |
E EQUITEC PROPRIETARY MARKETS, LLC Institution | $4.7M 3.2K contracts |
$4.3M 2.9K contracts | |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $1.9M 1.3K contracts |
N NOMURA HOLDINGS INC Institution | $1.6M 1.1K contracts |
 Caption Management, LLC Hedge Fund•Long/Short | $1.4M 944.0 contracts |
Most Committed Institutions
Institutions with ETNB as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
S SYQUANT CAPITAL SAS Institution | 17.74% $38.1M |
E EQUITEC PROPRIETARY MARKETS, LLC Institution | 11.42% $1.9M |
S SUPERSTRING CAPITAL MANAGEMENT LP Hedge Fund•Long/Short | 5.57% $5.7M |
O Omni Event Management Ltd Institution | 4.01% $34.5M |
 Orchard Capital Managment, LLC RIA/Wealth | 3.96% $3.0M |
Deep Track Capital, LP Hedge Fund•Long/Short | 3.91% $137.5M |
GLAZER CAPITAL, LLC Hedge Fund•Multi-Strategy | 3.76% $82.9M |
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | 3.69% $121.7M |
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short | 3.63% $292.4M |
 Black Maple Capital Management LP Hedge Fund•Multi-Strategy | 3.43% $4.7M |
Hedge Fund Spotlight
Discover hedge funds investing in ETNB
SUVRETTA CAPITAL MANAGEMENT, LLC
Hedge Fund • Long/Short
Portfolio ManagerAaron Leonard Cowen
- Portfolio Value
- $3.3B
- Positions
- 90
- Last Reported
- Q3 2025
Sector Allocation
Position in 89bio, Inc.
- Market Value
- $121.7M
- Shares Held
- 8.3M
- Portfolio Weight
- 3.69%
- Owned Since
- 2023-Q1
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Biotechnology Healthcare | $197.5M | 5.99% | |
Biotechnology Healthcare | $138.6M | 4.20% | |
Internet Content & Information Communication Services | $125.6M | 3.81% |
