Kiniksa Pharmaceuticals International, plc

KNSA • NASDAQ

Kiniksa Pharmaceuticals International, plc is a biotechnology company in the healthcare sector on NASDAQ, led by Sanj K. Patel, with a market cap of $3.2B. As of Q3 2025, 55% of shares are held by 201 institutional investors, with Rubric Capital Management LP as the largest holder at 5.4%.

Chief Executive OfficerSanj K. Patel

Market Cap$3.2B

Biotechnology

Healthcare

Employees297.0

Websitekiniksa.com

Country

United States of America

Overview

Overview of institutional ownership in KNSA as of Q3 2025 with a market cap of $2.9B

All Institutions

Institutions: 201
Value Held: $1.6B
Shares Held: 40.8M
Avg Position: $7.9M
Median Position: $803.8K

Hedge Funds

Hedge Funds: 41
Value Held: $665.1M
Shares Held: 17.1M
Avg Position: $16.2M
Median Position: $3.5M

Ownership Breakdown

Institutional (non-HF)

31.98%

$920.1M

Hedge Funds

23.11%

$665.1M

Retail & Other

44.91%

$1.3B

Based on market cap of $2.9B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in KNSA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
R Rubric Capital Management LP Hedge Fund•Long/Short	Margaret Kossakowski CFO	$155.3M 2.24% of portfolio	5.40% 4.0M shares	Q2 2022 Held for 3y 5m	$6.9B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$118.9M 0.00% of portfolio	4.13% 3.1M shares	Q2 2018 Held for 7y 5m	$6.69T
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	$109.7M 1.02% of portfolio	3.81% 2.8M shares	Q2 2018 Held for 7y 5m	$10.8B
T TANG CAPITAL MANAGEMENT LLC Institution	-	$90.4M 3.56% of portfolio	3.14% 2.3M shares	Q1 2022 Held for 3y 8m	$2.5B
Fairmount Funds Management LLC Hedge Fund•Sector	Peter Evan Harwin Managing Partner	$68.8M 6.19% of portfolio	2.39% 1.8M shares	Q2 2023 Held for 2y 5m	$1.1B
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	Gillian Morna Therese Savage CEO	$62.8M 0.12% of portfolio	2.18% 1.6M shares	Q4 2022 Held for 2y 11m	$51.5B
MORGAN STANLEY RIA/Wealth	Jed Finn CEO	$52.9M 0.00% of portfolio	1.84% 1.4M shares	Q2 2018 Held for 7y 5m	$1.65T
D D. E. Shaw & Co., Inc. Institution	-	$44.0M 0.04% of portfolio	1.53% 1.1M shares	Q4 2021 Held for 3y 11m	$115.81B
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	Anthony Ryan CEO	$41.5M 0.03% of portfolio	1.44% 1.1M shares	Q3 2023 Held for 2y 2m	$158.92B
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$39.4M 0.03% of portfolio	1.37% 1.0M shares	Q4 2019 Held for 5y 11m	$121.98B

Net Capital Flow

Institutional buying and selling activity for KNSA in Q3 2025

Traded: +$67.5M
Buyers: 110
Sellers: 95
Total Bought: +$231.8M
Total Sold: −$164.2M
Avg Position: $6.8M

Biggest Buyers

Institution	Net Bought	Current Position
N NOMURA HOLDINGS INC Institution	+$15.4M +397.1K shares	$15.4M 397.1K shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Long Only Manager	+$15.3M +394.1K shares	$17.8M 458.3K shares
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	+$13.6M +350.5K shares	$62.8M 1.6M shares
D D. E. Shaw & Co., Inc. Institution	+$13.3M +342.9K shares	$44.0M 1.1M shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	+$12.9M +332.8K shares	$41.5M 1.1M shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$11.6M +298.0K shares	$17.9M 461.8K shares
MORGAN STANLEY RIA/Wealth	+$11.5M +296.6K shares	$52.9M 1.4M shares
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	+$11.4M +293.2K shares	$16.0M 413.1K shares
B BNP PARIBAS ARBITRAGE, SA Institution	+$8.8M +227.5K shares	$25.4M 653.4K shares
BANK OF AMERICA CORP /DE/ Institution	+$8.7M +222.9K shares	$19.2M 495.5K shares

Biggest Sellers

Institution	Net Sold	Current Position
B BRAIDWELL LP Hedge Fund•Multi-Strategy	−$17.8M −459.4K shares	$25.0M 643.2K shares
S Squarepoint Ops LLC Hedge Fund•Quant	−$12.9M −331.4K shares	$3.3M 85.2K shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$10.9M −281.6K shares	$22.0M 566.9K shares
C Cubist Systematic Strategies, LLC Institution	−$10.7M −276.2K shares	$14.8M 381.3K shares
B BlackRock, Inc. Institution	−$9.5M −245.2K shares	$17.8M 457.6K shares
Q Qube Research & Technologies Ltd Institution	−$7.7M −198.5K shares	$26.8M 689.9K shares
ALGERT COLDIRON INVESTORS LLC Hedge Fund•Quant	−$7.6M −196.3K shares	$1.4M 35.8K shares
A Arrowpoint Asset Management, LLC Hedge Fund•Multi-Strategy	−$4.9M −125.3K shares	$13.2M 340.6K shares
J Jump Financial, LLC Institution	−$4.4M −113.1K shares	$4.4M 112.9K shares
Soleus Capital Management, L.P. Hedge Fund•Long/Short	−$4.1M −104.7K shares	$5.8M 150.0K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited KNSA in Q3 2025

New Positions: 32
New Value: $38.1M
Exited Positions: 31
Exited Value: $26.4M

New Positions

Institution	Position Value
N NOMURA HOLDINGS INC Institution	$15.4M 397.1K shares
S Standard Life Aberdeen plc Institution	$6.2M 158.7K shares
SILVERCREST ASSET MANAGEMENT GROUP LLC RIA/Wealth	$4.9M 126.3K shares
Voleon Capital Management LP Hedge Fund•Quant	$3.5M 89.2K shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	$2.3M 59.0K shares
Sheets Smith Investment Management RIA/Wealth	$659.8K 17.0K shares
MARK SHEPTOFF FINANCIAL PLANNING, LLC RIA/Wealth	$625.2K 16.1K shares
Q Quantedge Capital Pte Ltd Institution	$584.2K 15.0K shares
P Prosperity Wealth Management, Inc. RIA/Wealth	$539.7K 13.9K shares
Kingsview Wealth Management, LLC RIA/Wealth	$386.0K 9.9K shares

Exited Positions

Institution	Previous Position
GREAT LAKES ADVISORS, LLC Long Only Manager	$3.5M 126.8K shares
WELLINGTON MANAGEMENT CO LLP Long Only Manager	$3.2M 114.0K shares
Weiss Asset Management LP Hedge Fund•Multi-Strategy	$3.1M 111.7K shares
FRANKLIN RESOURCES INC Institution	$3.0M 108.6K shares
Hudson Bay Capital Management LP Hedge Fund•Multi-Strategy	$2.0M 70.8K shares
VICTORY CAPITAL MANAGEMENT INC Long Only Manager	$1.6M 59.0K shares
H HRT FINANCIAL LLC Institution	$1.4M 52.0K shares
UBS OCONNOR LLC Long Only Manager	$1.0M 37.6K shares
Knights of Columbus Asset Advisors LLC Long Only Manager	$902.7K 32.6K shares
SummitTX Capital, L.P. Hedge Fund•Multi-Strategy	$835.6K 30.2K shares

Options Activity

Institutions with the largest Call and Put options positions in KNSA as of Q3 2025

Call Positions: 4
Call Value: $23.9M
Put Positions: 5
Put Value: $3.8M

Call Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$19.5M 5.0K contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$3.5M 908.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$547.5K 141.0 contracts
J JANE STREET GROUP, LLC Institution	$275.7K 71.0 contracts

Put Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$3.5M 900.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$318.4K 82.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$3.9K 1.0 contracts
J JANE STREET GROUP, LLC Institution	- - contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	- - contracts

Most Committed Institutions

Institutions with KNSA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Fairmount Funds Management LLC Hedge Fund•Sector	Peter Evan Harwin Managing Partner	6.19% $68.8M	2.39% 1.8M shares	Q2 2023 Held for 2y 5m	$1.1B
L Lion Point Capital, LP Hedge Fund•Event Driven	Carl Didric Marcus Cederholm CIO	5.16% $908.6K	0.03% 23.4K shares	Q1 2020 Held for 5y 8m	$17.6M
T TANG CAPITAL MANAGEMENT LLC Institution	-	3.56% $90.4M	3.14% 2.3M shares	Q1 2022 Held for 3y 8m	$2.5B
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	Gregory Arthur Martinez CIO	2.87% $26.1M	0.91% 671.6K shares	Q4 2021 Held for 3y 11m	$910.1M
R Rubric Capital Management LP Hedge Fund•Long/Short	Margaret Kossakowski CFO	2.24% $155.3M	5.40% 4.0M shares	Q2 2022 Held for 3y 5m	$6.9B
ESSEX INVESTMENT MANAGEMENT CO LLC Long Only Manager	Nancy Beth Prial CEO	1.47% $9.6M	0.33% 247.3K shares	Q1 2023 Held for 2y 8m	$652.5M
R RICE HALL JAMES & ASSOCIATES, LLC Long Only Manager	Thomas W Mcdowell Chairman	1.22% $22.4M	0.78% 577.8K shares	Q4 2020 Held for 4y 11m	$1.8B
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	1.02% $109.7M	3.81% 2.8M shares	Q2 2018 Held for 7y 5m	$10.8B
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	1.01% $25.0M	0.87% 643.2K shares	Q1 2024 Held for 1y 8m	$2.5B
B Birchview Capital, LP Hedge Fund•Value	Matthew William Strobeck CIO	0.89% $1.2M	0.04% 30.0K shares	Q2 2021 Held for 4y 5m	$130.3M

Hedge Fund Spotlight

Discover hedge funds investing in KNSA

CITADEL ADVISORS LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerKenneth Cordele Griffin

Portfolio Value: $122.08B
Positions: 5,531
Last Reported: Q3 2025

Sector Allocation

Position in Kiniksa Pharmaceuticals International, plc

Market Value: $12.2M
Shares Held: 314.6K
Portfolio Weight: 0.01%
Owned Since: 2018-Q2

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