Lantheus Holdings

LNTH • NASDAQ

Lantheus Holdings is a drug manufacturers - specialty & generic company in the healthcare sector on NASDAQ, led by Brian Markison, with a market cap of $4.4B. As of Q3 2025, 105% of shares are held by 404 institutional investors, with BlackRock, Inc. as the largest holder at 12.16%.

Chief Executive OfficerBrian Markison

Market Cap$4.4B

Drug Manufacturers - Specialty & Generic

Healthcare

Employees834.0

Websitelantheus.com

Country

United States of America

Overview

Overview of institutional ownership in LNTH as of Q3 2025 with a market cap of $3.5B

All Institutions

Institutions: 404
Value Held: $3.7B
Shares Held: 71.2M
Avg Position: $9.0M
Median Position: $734.1K

Hedge Funds

Hedge Funds: 40
Value Held: $342.1M
Shares Held: 6.7M
Avg Position: $8.6M
Median Position: $917.7K

Ownership Breakdown

Institutional (non-HF)

94.99%

$3.3B

Hedge Funds

9.81%

$342.1M

Retail & Other

Based on market cap of $3.5B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in LNTH as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$424.0M 0.01% of portfolio	12.16% 8.3M shares	Q1 2016 Held for 9y 8m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$356.6M 0.01% of portfolio	10.23% 7.0M shares	Q3 2015 Held for 10y 2m	$6.69T
HENDERSON GROUP PLC Institution	Ali Dibadj CEO	$342.9M 0.16% of portfolio	9.83% 6.7M shares	Q4 2021 Held for 3y 11m	$218.74B
FMR LLC Institution	-	$215.4M 0.01% of portfolio	6.18% 4.2M shares	Q3 2018 Held for 7y 2m	$1.92T
MORGAN STANLEY RIA/Wealth	Jed Finn CEO	$198.9M 0.01% of portfolio	5.70% 3.9M shares	Q3 2015 Held for 10y 2m	$1.65T
FARALLON CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	Edric Calvin Saito Managing Partner	$178.3M 1.01% of portfolio	5.11% 3.5M shares	Q1 2023 Held for 2y 8m	$17.7B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$128.1M 0.00% of portfolio	3.67% 2.5M shares	Q1 2017 Held for 8y 8m	$2.88T
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$90.0M 0.01% of portfolio	2.58% 1.8M shares	Q3 2015 Held for 10y 2m	$1.57T
DIMENSIONAL FUND ADVISORS LP Long Only Manager	David Paul Butler CEO	$70.3M 0.02% of portfolio	2.02% 1.4M shares	Q1 2017 Held for 8y 8m	$466.32B
REINHART MAHONEY CAPITAL MANAGEMENT INC Long Only Manager	James Everett Reinhart CEO	$69.1M 2.25% of portfolio	1.98% 1.3M shares	Q1 2021 Held for 4y 8m	$3.1B

Net Capital Flow

Institutional buying and selling activity for LNTH in Q3 2025

Traded: −$527.7M
Buyers: 180
Sellers: 299
Total Bought: +$541.9M
Total Sold: −$1.1B
Avg Position: $6.9M

Biggest Buyers

Institution	Net Bought	Current Position
MORGAN STANLEY RIA/Wealth	+$160.9M +3.1M shares	$198.9M 3.9M shares
A Assenagon Asset Management S.A. Institution	+$65.7M +1.3M shares	$65.7M 1.3M shares
Polaris Capital Management, Inc. Long Only Manager	+$32.7M +637.3K shares	$32.7M 637.3K shares
C Carmignac Gestion Institution	+$26.2M +510.4K shares	$41.4M 807.4K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$18.0M +351.3K shares	$22.7M 443.5K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$14.5M +282.3K shares	$26.6M 519.4K shares
J JANE STREET GROUP, LLC Institution	+$13.7M +266.2K shares	$13.9M 270.7K shares
HOTCHKIS & WILEY CAPITAL MANAGEMENT LLC Long Only Manager	+$11.4M +223.1K shares	$11.4M 223.1K shares
B BNP PARIBAS ARBITRAGE, SA Institution	+$10.0M +195.9K shares	$33.8M 659.3K shares
UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager	+$9.7M +189.8K shares	$23.0M 448.5K shares

Biggest Sellers

Institution	Net Sold	Current Position
FARALLON CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$166.4M −3.2M shares	$178.3M 3.5M shares
WESTFIELD CAPITAL MANAGEMENT CO LP Long Only Manager	−$122.4M −1.5M shares	Sold Off 0 shares
Invesco Ltd. ETF Provider	−$48.8M −950.8K shares	$37.6M 733.0K shares
WELLINGTON MANAGEMENT CO LLP Long Only Manager	−$48.6M −947.4K shares	$39.6M 772.0K shares
Robeco Investment Management, Inc. Long Only Manager	−$46.4M −576.4K shares	Sold Off 0 shares
FMR LLC Institution	−$42.1M −820.1K shares	$215.4M 4.2M shares
Hood River Capital Management LLC Long Only Manager	−$33.3M −407.2K shares	Sold Off 0 shares
N Nitorum Capital, L.P. Hedge Fund•Long/Short	−$28.2M −344.4K shares	Sold Off 0 shares
SILVERCREST ASSET MANAGEMENT GROUP LLC RIA/Wealth	−$28.1M −546.9K shares	$24.1M 469.5K shares
FRONTIER CAPITAL MANAGEMENT CO LLC Long Only Manager	−$25.8M −315.5K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited LNTH in Q3 2025

New Positions: 29
New Value: $59.7M
Exited Positions: 124
Exited Value: $458.5M

New Positions

Institution	Position Value
Polaris Capital Management, Inc. Long Only Manager	$32.7M 637.3K shares
HOTCHKIS & WILEY CAPITAL MANAGEMENT LLC Long Only Manager	$11.4M 223.1K shares
N Nearwater Capital Markets, Ltd Institution	$6.1M 119.6K shares
IMC-Chicago, LLC RIA/Wealth	$2.0M 39.3K shares
I ISTHMUS PARTNERS, LLC RIA/Wealth	$1.2M 24.1K shares
W Waterfront Wealth Inc. RIA/Wealth	$1.1M 18.5K shares
E Elo Mutual Pension Insurance Co Institution	$942.2K 18.4K shares
A AMERICAN ASSETS INC Institution	$871.9K 17.0K shares
Heron Bay Capital Management RIA/Wealth	$861.3K 16.8K shares
Numerai GP LLC Hedge Fund•Quant	$659.6K 12.9K shares

Exited Positions

Institution	Previous Position
WESTFIELD CAPITAL MANAGEMENT CO LP Long Only Manager	$122.4M 1.5M shares
Robeco Investment Management, Inc. Long Only Manager	$46.4M 576.4K shares
Hood River Capital Management LLC Long Only Manager	$33.3M 407.2K shares
N Nitorum Capital, L.P. Hedge Fund•Long/Short	$28.2M 344.4K shares
FRONTIER CAPITAL MANAGEMENT CO LLC Long Only Manager	$25.8M 315.5K shares
Clearbridge Investments, LLC Long Only Manager	$18.2M 222.1K shares
E EAGLE GLOBAL ADVISORS LLC Hedge Fund•Multi-Strategy	$14.8M 181.2K shares
SHAPIRO CAPITAL MANAGEMENT CO INC Long Only Manager	$14.4M 176.5K shares
Galvin, Gaustad & Stein, LLC RIA/Wealth	$11.9M 145.4K shares
JUPITER ASSET MANAGEMENT LTD Long Only Manager	$11.2M 136.4K shares

Options Activity

Institutions with the largest Call and Put options positions in LNTH as of Q3 2025

Call Positions: 16
Call Value: $20.3M
Put Positions: 13
Put Value: $16.1M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$7.7M 1.5K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$4.8M 945.0 contracts
C Cubist Systematic Strategies, LLC Institution	$1.8M 342.0 contracts
J JANE STREET GROUP, LLC Institution	$1.4M 274.0 contracts
W WOLVERINE TRADING, LLC Institution	$1.3M 248.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$1.0M 203.0 contracts
TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy	$800.1K 156.0 contracts
T Twin Tree Management, LP Hedge Fund•Vol Arbitrage	$620.6K 121.0 contracts
Walleye Trading LLC RIA/Wealth	$615.5K 120.0 contracts
D D. E. Shaw & Co., Inc. Institution	$200.0K 39.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$5.2M 1.0K contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$5.1M 1.0K contracts
J JANE STREET GROUP, LLC Institution	$2.0M 395.0 contracts
W WOLVERINE TRADING, LLC Institution	$1.1M 221.0 contracts
P PEAK6 LLC Institution	$928.3K 181.0 contracts
TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy	$846.3K 165.0 contracts
T Twin Tree Management, LP Hedge Fund•Vol Arbitrage	$415.4K 81.0 contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	$251.3K 49.0 contracts
Walleye Trading LLC RIA/Wealth	$169.3K 33.0 contracts
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	- - contracts

Most Committed Institutions

Institutions with LNTH as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
BRIGADE CAPITAL MANAGEMENT, LLC Hedge Fund•Multi-Strategy	Raymond (Nmn) Luis President	16.20% $16.2M	0.47% 316.3K shares	Q2 2025 Held for 5 months	$100.1M
Sarissa Capital Management LP Hedge Fund•Activist	Alexander John Denner CEO	5.16% $9.3M	0.27% 181.5K shares	Q3 2024 Held for 1y 2m	$180.4M
V Velan Capital Investment Management LP Institution	-	3.54% $3.8M	0.11% 73.5K shares	Q3 2025 Held for 2 months	$106.5M
Private Capital Management, LLC RIA/Wealth	Gregg Joseph Powers CEO	2.91% $28.8M	0.82% 560.7K shares	Q2 2020 Held for 5y 5m	$986.6M
REINHART MAHONEY CAPITAL MANAGEMENT INC Long Only Manager	James Everett Reinhart CEO	2.25% $69.1M	1.98% 1.3M shares	Q1 2021 Held for 4y 8m	$3.1B
Polaris Capital Management, Inc. Long Only Manager	Bernard Robert Horn President	2.14% $32.7M	0.94% 637.3K shares	Q3 2025 Held for 2 months	$1.5B
E Expect Equity LLC Institution	-	1.36% $1.4M	0.04% 27.2K shares	Q4 2024 Held for 11 months	$102.4M
FARALLON CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	Edric Calvin Saito Managing Partner	1.01% $178.3M	5.11% 3.5M shares	Q1 2023 Held for 2y 8m	$17.7B
S Silverberg Bernstein Capital Management LLC RIA/Wealth	Irwin Warren Silverberg Managing Partner	0.92% $1.5M	0.04% 29.4K shares	Q4 2023 Held for 1y 11m	$163.4M
Portolan Capital Management, LLC Hedge Fund•Long/Short	George Frederic Mccabe CIO	0.82% $15.2M	0.44% 297.2K shares	Q1 2023 Held for 2y 8m	$1.8B

Hedge Fund Spotlight

Discover hedge funds investing in LNTH

Bayforest Capital Ltd

Hedge Fund • Quant

Portfolio ManagerTheodoros Tsagaris

Portfolio Value: $209.9M
Positions: 718
Last Reported: Q3 2025

Sector Allocation

Position in Lantheus Holdings

Market Value: $572.0K
Shares Held: 11.2K
Portfolio Weight: 0.27%
Owned Since: 2025-Q1

Top Holding	Sector	Market Value	Weight
1 SolarEdge Technologies SEDG	Solar Energy	$1.5M	0.72%
2 Peloton Interactive, Inc. PTON	Leisure Consumer Cyclical	$1.3M	0.64%
3 Crown Castle CCI	REIT - Specialty Real Estate	$1.3M	0.62%