M
Mereo BioPharma Group plc
MREO • NASDAQ
Mereo BioPharma Group plc is a pharmaceutical preparations company on NASDAQ. As of Q3 2025, 75 institutional investors hold shares in this company, with total holdings valued at $200.4M. HENDERSON GROUP PLC is the largest holder with a position valued at $33.6M.
Overview
Overview of institutional ownership in MREO as of Q3 2025
All Institutions
- Institutions
- 75
- Value Held
- $200.4M
- Shares Held
- 97.9M
- Avg Position
- $2.7M
- Median Position
- $213.8K
Hedge Funds
- Hedge Funds
- 20
- Value Held
- $100.1M
- Shares Held
- 48.6M
- Avg Position
- $5.0M
- Median Position
- $1.1M
Biggest Investors
Institutions with the largest positions in MREO as of Q3 2025
| Institution | Position Value |
|---|---|
 HENDERSON GROUP PLC Institution | $33.6M 0.02% of portfolio |
R Rubric Capital Management LP Hedge Fund•Long/Short | $31.5M 0.45% of portfolio |
 Frazier Life Sciences Management, L.P. Venture Capital | $19.4M 0.58% of portfolio |
 MANGROVE PARTNERS Hedge Fund•Multi-Strategy | $16.0M 1.13% of portfolio |
S Standard Life Aberdeen plc Institution | $11.4M 0.02% of portfolio |
6 683 Capital Management, LLC Hedge Fund•Long/Short | $10.0M 0.95% of portfolio |
 Rock Springs Capital Management LP Hedge Fund•Sector | $9.4M 0.55% of portfolio |
C Clearline Capital LP Hedge Fund•Event Driven | $7.9M 0.67% of portfolio |
A ALKEON CAPITAL MANAGEMENT LLC Hedge Fund•Long/Short | $7.6M 0.03% of portfolio |
 MORGAN STANLEY RIA/Wealth | $6.9M 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for MREO in Q3 2025
- Traded
- −$5.4M
- Buyers
- 30
- Sellers
- 34
- Total Bought
- +$27.8M
- Total Sold
- −$33.2M
- Avg Position
- $2.2M
Biggest Buyers
| Institution | Net Bought |
|---|---|
MORGAN STANLEY RIA/Wealth | +$5.3M +2.6M shares |
S Standard Life Aberdeen plc Institution | +$5.2M +2.5M shares |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | +$5.0M +2.4M shares |
 UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager | +$3.9M +1.9M shares |
 Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy | +$1.7M +823.1K shares |
 UBS Group AG Institution | +$1.2M +597.2K shares |
 Monaco Asset Management SAM RIA/Wealth | +$1.1M +550.9K shares |
6 683 Capital Management, LLC Hedge Fund•Long/Short | +$1.1M +525.0K shares |
 TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | +$883.6K +428.9K shares |
C Clearline Capital LP Hedge Fund•Event Driven | +$445.0K +216.0K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short | −$18.2M −6.7M shares |
HENDERSON GROUP PLC Institution | −$2.9M −1.4M shares |
A ALKEON CAPITAL MANAGEMENT LLC Hedge Fund•Long/Short | −$2.1M −1.0M shares |
 RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | −$1.8M −889.6K shares |
MANGROVE PARTNERS Hedge Fund•Multi-Strategy | −$1.7M −845.9K shares |
 GOLDMAN SACHS GROUP INC Institution | −$1.5M −726.0K shares |
T Tejara Capital Ltd Institution | −$1.1M −523.6K shares |
 SUNRISE PARTNERS LIMITED PARTNERSHIP /CT Hedge Fund•Multi-Strategy | −$803.9K −296.7K shares |
 Soleus Capital Management, L.P. Hedge Fund•Long/Short | −$618.0K −300.0K shares |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$531.8K −258.2K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited MREO in Q3 2025
- New Positions
- 6
- New Value
- $146.5K
- Exited Positions
- 14
- Exited Value
- $19.8M
New Positions
| Institution | Position Value |
|---|---|
 Forefront Wealth Partners, LLC RIA/Wealth | $68.4K 33.2K shares |
 Federation des caisses Desjardins du Quebec Fund of Funds | $43.8K 21.3K shares |
S State of New Jersey Common Pension Fund D Institution | $32.2K 15.6K shares |
 Sontag Advisory, LLC RIA/Wealth | $2.1K 1.0K shares |
N NEOS Investment Management LLC Institution | - - shares |
T TEMA ETFS LLC Institution | - - shares |
Exited Positions
| Institution | Previous Position |
|---|---|
DEERFIELD MANAGEMENT CO /NY Hedge Fund•Long/Short | $18.2M 6.7M shares |
SUNRISE PARTNERS LIMITED PARTNERSHIP /CT Hedge Fund•Multi-Strategy | $803.9K 296.7K shares |
D Dauntless Investment Group, LLC Institution | $363.5K 134.1K shares |
 Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | $160.4K 59.2K shares |
J J. Goldman & Co LP Hedge Fund•Multi-Strategy | $142.0K 52.4K shares |
Q Quadrature Capital Ltd Institution | $69.1K 25.4K shares |
 Graham Capital Management, L.P. Hedge Fund•Multi-Strategy | $57.4K 21.2K shares |
C Cubist Systematic Strategies, LLC Institution | $57.2K 21.1K shares |
 RAYMOND JAMES FINANCIAL INC RIA/Wealth | $4.3K 1.6K shares |
S Skopos Labs, Inc. RIA/Wealth | $2.3K 849.0 shares |
Options Activity
Institutions with the largest Call and Put options positions in MREO as of Q3 2025
- Call Positions
- 10
- Call Value
- $4.6M
- Put Positions
- 5
- Put Value
- $368.5K
Call Positions
| Institution | Position Value |
|---|---|
 DIADEMA PARTNERS LP Hedge Fund•Long/Short | $3.1M 15.2K contracts |
 Caption Management, LLC Hedge Fund•Long/Short | $783.8K 3.8K contracts |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $309.6K 1.5K contracts |
 DLD Asset Management, LP Hedge Fund•Multi-Strategy | $245.1K 1.2K contracts |
J JANE STREET GROUP, LLC Institution | $66.3K 322.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $52.9K 257.0 contracts |
 BARCLAYS PLC Institution | $11.5K 56.0 contracts |
P Persistent Asset Partners Ltd Institution | - - contracts |
L LMR Partners LLP Institution | - - contracts |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | - - contracts |
Put Positions
| Institution | Position Value |
|---|---|
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $118.9K 577.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $113.9K 553.0 contracts |
DIADEMA PARTNERS LP Hedge Fund•Long/Short | $81.2K 394.0 contracts |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $54.6K 265.0 contracts |
J JANE STREET GROUP, LLC Institution | - - contracts |
Most Committed Institutions
Institutions with MREO as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
T Tejara Capital Ltd Institution | 2.15% $3.9M |
MANGROVE PARTNERS Hedge Fund•Multi-Strategy | 1.13% $16.0M |
6 683 Capital Management, LLC Hedge Fund•Long/Short | 0.95% $10.0M |
Monaco Asset Management SAM RIA/Wealth | 0.76% $1.9M |
C Clearline Capital LP Hedge Fund•Event Driven | 0.67% $7.9M |
H HealthInvest Partners AB Institution | 0.65% $167.3K |
Frazier Life Sciences Management, L.P. Venture Capital | 0.58% $19.4M |
Rock Springs Capital Management LP Hedge Fund•Sector | 0.55% $9.4M |
R Rubric Capital Management LP Hedge Fund•Long/Short | 0.45% $31.5M |
K Knoll Capital Management, LP Institution | 0.29% $536.6K |
Hedge Fund Spotlight
Discover hedge funds investing in MREO
S
Squarepoint Ops LLC
Hedge Fund • Quant
Portfolio ManagerMichael Gottlieb
- Portfolio Value
- $46.9B
- Positions
- 2,529
- Last Reported
- Q3 2025
Sector Allocation
M
Position in Mereo BioPharma Group plc
- Market Value
- $61.9K
- Shares Held
- 30.1K
- Portfolio Weight
- 0.00%
- Owned Since
- 2023-Q4
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
ETF ETF | $5.5B | 11.75% | |
Specialty Retail Consumer Cyclical | $983.1M | 2.10% | |
Semiconductors Technology | $935.8M | 2.00% |
