Pacira BioSciences, Inc.

PCRX • NASDAQ

Pacira BioSciences, Inc. is a drug manufacturers - specialty & generic company in the healthcare sector on NASDAQ, led by Frank Lee, with a market cap of $1.1B. As of Q3 2025, 106% of shares are held by 236 institutional investors, with BlackRock, Inc. as the largest holder at 16.33%.

Chief Executive OfficerFrank Lee

Market Cap$1.1B

Drug Manufacturers - Specialty & Generic

Healthcare

Employees712.0

Websitepacira.com

Country

United States of America

Overview

Overview of institutional ownership in PCRX as of Q3 2025 with a market cap of $1.2B

All Institutions

Institutions: 236
Value Held: $1.2B
Shares Held: 47.8M
Avg Position: $5.2M
Median Position: $507.5K

Hedge Funds

Hedge Funds: 28
Value Held: $251.8M
Shares Held: 9.8M
Avg Position: $9.0M
Median Position: $1.5M

Ownership Breakdown

Institutional (non-HF)

84.73%

$981.1M

Hedge Funds

21.75%

$251.8M

Retail & Other

Based on market cap of $1.2B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in PCRX as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$189.1M 0.00% of portfolio	16.33% 7.3M shares	≤ Q2 2013 Held for 12y 5m+	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$133.9M 0.00% of portfolio	11.57% 5.2M shares	≤ Q2 2013 Held for 12y 5m+	$6.69T
Doma Perpetual Capital Management LLC Hedge Fund•Value	Pedro Escudero CEO	$69.6M 23.38% of portfolio	6.01% 2.7M shares	Q4 2023 Held for 1y 11m	$297.8M
DIMENSIONAL FUND ADVISORS LP Long Only Manager	David Paul Butler CEO	$55.8M 0.01% of portfolio	4.81% 2.2M shares	Q3 2018 Held for 7y 2m	$466.32B
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	$55.1M 0.07% of portfolio	4.76% 2.1M shares	Q3 2018 Held for 7y 2m	$75.8B
D D. E. Shaw & Co., Inc. Institution	-	$50.0M 0.04% of portfolio	4.32% 1.9M shares	Q1 2023 Held for 2y 8m	$115.81B
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$49.0M 0.00% of portfolio	4.23% 1.9M shares	≤ Q2 2013 Held for 12y 5m+	$2.88T
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dmitry Balyasny CIO	$48.6M 0.10% of portfolio	4.20% 1.9M shares	Q4 2024 Held for 11 months	$48.1B
A AMERICAN CENTURY COMPANIES INC Institution	-	$35.5M 0.02% of portfolio	3.07% 1.4M shares	Q2 2023 Held for 2y 5m	$195.93B
GOLDMAN SACHS GROUP INC Institution	David M. Solomon CEO	$33.8M 0.00% of portfolio	2.92% 1.3M shares	≤ Q2 2013 Held for 12y 5m+	$691.34B

Net Capital Flow

Institutional buying and selling activity for PCRX in Q3 2025

Traded: −$63.6M
Buyers: 104
Sellers: 124
Total Bought: +$109.3M
Total Sold: −$173.0M
Avg Position: $4.6M

Biggest Buyers

Institution	Net Bought	Current Position
Doma Perpetual Capital Management LLC Hedge Fund•Value	+$23.1M +897.3K shares	$69.6M 2.7M shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	+$10.6M +410.0K shares	$10.6M 410.0K shares
A AMERICAN CENTURY COMPANIES INC Institution	+$5.1M +196.0K shares	$35.5M 1.4M shares
MORGAN STANLEY RIA/Wealth	+$5.0M +192.7K shares	$29.4M 1.1M shares
R ROYAL BANK OF CANADA Institution	+$4.4M +169.2K shares	$9.6M 370.7K shares
Bridge City Capital, LLC Long Only Manager	+$3.7M +141.8K shares	$8.0M 311.4K shares
I Impax Asset Management Group plc Long Only Manager	+$3.4M +130.0K shares	$15.5M 600.0K shares
VOLORIDGE INVESTMENT MANAGEMENT, LLC Hedge Fund•Multi-Strategy	+$3.3M +127.2K shares	$6.8M 262.7K shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$3.3M +126.2K shares	$6.0M 233.0K shares
H HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND Institution	+$3.0M +117.6K shares	$7.6M 293.0K shares

Biggest Sellers

Institution	Net Sold	Current Position
Polar Capital Holdings Plc Long Only Manager	−$21.8M −910.5K shares	Sold Off 0 shares
B BlackRock, Inc. Institution	−$11.8M −459.8K shares	$189.1M 7.3M shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$11.4M −444.3K shares	$1.8M 70.8K shares
EcoR1 Capital, LLC Hedge Fund•Sector	−$10.9M −457.5K shares	Sold Off 0 shares
JACOBS LEVY EQUITY MANAGEMENT, INC Hedge Fund•Quant	−$8.6M −332.2K shares	$16.8M 652.6K shares
D D. E. Shaw & Co., Inc. Institution	−$8.0M −311.2K shares	$50.0M 1.9M shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	−$6.6M −257.4K shares	$55.1M 2.1M shares
A Assenagon Asset Management S.A. Institution	−$6.5M −250.6K shares	$6.0M 232.4K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$6.3M −245.7K shares	$48.6M 1.9M shares
S Siren, L.L.C. Institution	−$5.4M −225.0K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited PCRX in Q3 2025

New Positions: 12
New Value: $2.3M
Exited Positions: 30
Exited Value: $61.2M

New Positions

Institution	Position Value
Radcliffe Capital Management, L.P. Hedge Fund•Multi-Strategy	$1.2M 47.6K shares
FOSTER & MOTLEY INC RIA/Wealth	$388.4K 15.1K shares
Empirical Financial Services, LLC RIA/Wealth	$333.9K 13.0K shares
Virtus ETF Advisers LLC Long Only Manager	$174.3K 6.8K shares
ISAM Funds Ltd Hedge Fund•Quant	$79.6K 3.1K shares
T Tidemark, LLC RIA/Wealth	$55.9K 2.2K shares
S Salomon & Ludwin, LLC Institution	$8.3K 334.0 shares
O Optiver Holding B.V. Institution	$5.6K 218.0 shares
HARBOR CAPITAL ADVISORS, INC. ETF Provider	$4.7K 183.0 shares
CALDWELL SUTTER CAPITAL, INC. RIA/Wealth	$3.8K 149.0 shares

Exited Positions

Institution	Previous Position
Polar Capital Holdings Plc Long Only Manager	$21.8M 910.5K shares
EcoR1 Capital, LLC Hedge Fund•Sector	$10.9M 457.5K shares
S Siren, L.L.C. Institution	$5.4M 225.0K shares
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy	$4.8M 200.8K shares
Marshall Wace LLP Institution	$4.5M 190.4K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$2.9M 123.1K shares
A AXA Institution	$2.8M 117.3K shares
W Winton Capital Group Ltd Institution	$2.5M 102.7K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	$2.2M 90.1K shares
Verition Fund Management LLC Hedge Fund•Multi-Strategy	$661.1K 27.7K shares

Options Activity

Institutions with the largest Call and Put options positions in PCRX as of Q3 2025

Call Positions: 6
Call Value: $3.0M
Put Positions: 3
Put Value: $649.4K

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$1.4M 553.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.1M 420.0 contracts
W WOLVERINE TRADING, LLC Institution	$288.9K 114.0 contracts
J JANE STREET GROUP, LLC Institution	$229.4K 89.0 contracts
Caption Management, LLC Hedge Fund•Long/Short	- - contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	- - contracts

Put Positions

Institution	Position Value
WOLVERINE ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	$649.4K 252.0 contracts
J JANE STREET GROUP, LLC Institution	- - contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	- - contracts

Most Committed Institutions

Institutions with PCRX as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Doma Perpetual Capital Management LLC Hedge Fund•Value	Pedro Escudero CEO	23.38% $69.6M	6.01% 2.7M shares	Q4 2023 Held for 1y 11m	$297.8M
G Gagnon Advisors, LLC Hedge Fund•Long/Short	Neil Joseph Gagnon CEO	3.40% $5.5M	0.47% 213.4K shares	Q2 2019 Held for 6y 5m	$162.0M
GAGNON SECURITIES LLC RIA/Wealth	Neil Joseph Gagnon CEO	2.35% $11.6M	1.00% 449.7K shares	Q2 2019 Held for 6y 5m	$493.8M
Bridge City Capital, LLC Long Only Manager	Alexander Jackson Woodward President	2.14% $8.0M	0.69% 311.4K shares	Q1 2024 Held for 1y 8m	$374.5M
DIADEMA PARTNERS LP Hedge Fund•Long/Short	Timothy Beau Bassett CIO	1.06% $1.5M	0.13% 58.9K shares	Q1 2025 Held for 8 months	$143.3M
J J. Goldman & Co LP Hedge Fund•Multi-Strategy	Jay Glenn Goldman CEO	0.65% $17.2M	1.49% 669.1K shares	Q4 2024 Held for 11 months	$2.6B
H HUSSMAN STRATEGIC ADVISORS, INC. Institution	John Peter Hussman President	0.59% $2.7M	0.23% 105.0K shares	Q3 2025 Held for 2 months	$458.6M
Phocas Financial Corp. Long Only Manager	William Franz Kim Schaff CEO	0.49% $3.8M	0.33% 146.9K shares	Q1 2025 Held for 8 months	$771.4M
Levin Easterly Partners LLC Long Only Manager	Darrell William Crate Chairman	0.43% $6.4M	0.55% 249.1K shares	Q3 2023 Held for 2y 2m	$1.5B
R RICE HALL JAMES & ASSOCIATES, LLC Long Only Manager	Thomas W Mcdowell Chairman	0.33% $6.1M	0.53% 237.0K shares	Q2 2015 Held for 10y 5m	$1.8B

Hedge Fund Spotlight

Discover hedge funds investing in PCRX

CAPSTONE INVESTMENT ADVISORS, LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerPaul Matthew Britton

Portfolio Value: $9.4B
Positions: 1,012
Last Reported: Q3 2025

Sector Allocation

Position in Pacira BioSciences, Inc.

Market Value: $494.0K
Shares Held: 19.2K
Portfolio Weight: 0.01%
Owned Since: 2025-Q3

Top Holding	Sector	Market Value	Weight
1 Nvidia NVDA	Semiconductors Technology	$1.3B	13.35%
2 Microsoft MSFT	Software - Infrastructure Technology	$1.1B	11.84%
3 Amazon AMZN	Specialty Retail Consumer Cyclical	$1.0B	11.12%