ProQR Therapeutics
PRQR • NASDAQ
ProQR Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by Daniel de Boer, with a market cap of $245.5M. As of Q3 2025, 36% of shares are held by 63 institutional investors, with ADAGE CAPITAL PARTNERS GP LLC as the largest holder at 5.94%.
CEODaniel de Boer
Overview
Overview of institutional ownership in PRQR as of Q3 2025 with a market cap of $224.4M
All Institutions
- Institutions
- 63
- Value Held
- $80.0M
- Shares Held
- 37.5M
- Avg Position
- $1.3M
- Median Position
- $196.4K
Hedge Funds
- Hedge Funds
- 18
- Value Held
- $32.7M
- Shares Held
- 15.3M
- Avg Position
- $1.8M
- Median Position
- $1.3M
Ownership Breakdown
Based on market cap of $224.4M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in PRQR as of Q3 2025
| Institution | Position Value |
|---|---|
A ADAGE CAPITAL PARTNERS GP LLC Institution | $13.3M 0.02% of portfolio |
P Privium Fund Management B.V. Institution | $10.6M 1.91% of portfolio |
 Affinity Asset Advisors, LLC Hedge Fund•Long/Short | $7.7M 0.78% of portfolio |
 MORGAN STANLEY RIA/Wealth | $6.2M 0.00% of portfolio |
S Standard Life Aberdeen plc Institution | $4.9M 0.01% of portfolio |
 Sio Capital Management, LLC Hedge Fund•Long/Short | $4.4M 1.12% of portfolio |
K Kynam Capital Management, LP Hedge Fund•Long/Short | $3.5M 0.26% of portfolio |
D DAFNA Capital Management LLC Hedge Fund•Event Driven | $3.3M 0.84% of portfolio |
S Siren, L.L.C. Institution | $3.3M 0.14% of portfolio |
A Arrowpoint Asset Management, LLC Hedge Fund•Multi-Strategy | $2.7M 0.05% of portfolio |
Net Capital Flow
Institutional buying and selling activity for PRQR in Q3 2025
- Traded
- −$558.6K
- Buyers
- 24
- Sellers
- 17
- Total Bought
- +$3.8M
- Total Sold
- −$4.4M
- Avg Position
- $1.1M
Biggest Buyers
| Institution | Net Bought |
|---|---|
S Standard Life Aberdeen plc Institution | +$955.3K +448.5K shares |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | +$591.6K +277.7K shares |
 TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | +$411.6K +193.3K shares |
P Palo Alto Investors, LLC Hedge Fund•Long/Short | +$402.2K +188.8K shares |
Affinity Asset Advisors, LLC Hedge Fund•Long/Short | +$214.0K +100.5K shares |
 UBS Group AG Institution | +$201.4K +-1.0M shares |
 Woodline Partners LP Hedge Fund•Long/Short | +$196.3K +-1.4M shares |
 TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy | +$188.1K +88.3K shares |
C Cubist Systematic Strategies, LLC Institution | +$102.5K +48.1K shares |
A Arrowpoint Asset Management, LLC Hedge Fund•Multi-Strategy | +$99.2K +46.6K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$2.3M −1.1M shares |
A ADAGE CAPITAL PARTNERS GP LLC Institution | −$742.2K −348.5K shares |
 PLATINUM INVESTMENT MANAGEMENT LTD Long Only Manager | −$458.9K −215.5K shares |
MORGAN STANLEY RIA/Wealth | −$388.3K −182.3K shares |
 NORTHERN TRUST CORP Institution | −$213.1K −100.0K shares |
V Vontobel Holding Ltd. Institution | −$130.5K −64.0K shares |
 BANK OF MONTREAL /CAN/ Institution | −$61.2K −30.0K shares |
R ROYAL BANK OF CANADA Institution | −$43.0K −20.2K shares |
H HRT FINANCIAL LLC Institution | −$25.1K −12.3K shares |
 Engineers Gate Manager LP Hedge Fund•Quant | −$21.9K −10.7K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited PRQR in Q3 2025
- New Positions
- 2
- New Value
- $402.2K
- Exited Positions
- 7
- Exited Value
- $251.0K
New Positions
| Institution | Position Value |
|---|---|
P Palo Alto Investors, LLC Hedge Fund•Long/Short | $402.2K 188.8K shares |
 Rockefeller Capital Management L.P. Long Only Manager | $72.0 34.0 shares |
Exited Positions
| Institution | Previous Position |
|---|---|
V Vontobel Holding Ltd. Institution | $130.5K 64.0K shares |
BANK OF MONTREAL /CAN/ Institution | $61.2K 30.0K shares |
H HRT FINANCIAL LLC Institution | $25.1K 12.3K shares |
Engineers Gate Manager LP Hedge Fund•Quant | $21.9K 10.7K shares |
G GROUP ONE TRADING, L.P. Institution | $7.2K 3.5K shares |
 Flaharty Asset Management, LLC RIA/Wealth | $4.1K 2.0K shares |
S SIMPLEX TRADING, LLC Institution | $1.0K 856.0 shares |
Options Activity
Institutions with the largest Call and Put options positions in PRQR as of Q3 2025
- Call Positions
- 1
- Call Value
- -
- Put Positions
- 0
- Put Value
- -
Call Positions
| Institution | Position Value |
|---|---|
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | - - contracts |
Put Positions
| Institution | Position Value |
|---|---|
| No put positions found | |
Most Committed Institutions
Institutions with PRQR as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
 M28 Capital Management LP Hedge Fund•Long/Short | 3.19% $2.2M |
P Privium Fund Management B.V. Institution | 1.91% $10.6M |
Sio Capital Management, LLC Hedge Fund•Long/Short | 1.12% $4.4M |
D DAFNA Capital Management LLC Hedge Fund•Event Driven | 0.84% $3.3M |
Affinity Asset Advisors, LLC Hedge Fund•Long/Short | 0.78% $7.7M |
 Ikarian Capital, LLC Hedge Fund•Event Driven | 0.38% $1.9M |
 Monaco Asset Management SAM RIA/Wealth | 0.38% $979.8K |
K Kynam Capital Management, LP Hedge Fund•Long/Short | 0.26% $3.5M |
 DIADEMA PARTNERS LP Hedge Fund•Long/Short | 0.23% $335.9K |
PLATINUM INVESTMENT MANAGEMENT LTD Long Only Manager | 0.17% $2.6M |
Hedge Fund Spotlight
Discover hedge funds investing in PRQR
K
Kynam Capital Management, LP
Hedge Fund • Long/Short
Portfolio ManagerJared Joseph Keller
- Portfolio Value
- $1.3B
- Positions
- 35
- Last Reported
- Q3 2025
Sector Allocation
Position in ProQR Therapeutics
- Market Value
- $3.5M
- Shares Held
- 1.6M
- Portfolio Weight
- 0.26%
- Owned Since
- 2024-Q4
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Biotechnology Healthcare | $157.8M | 11.75% | |
Biotechnology Healthcare | $131.1M | 9.76% | |
Biotechnology Healthcare | $117.0M | 8.71% |
