SOPHiA GENETICS SA is a medical - healthcare information services company in the healthcare sector on NASDAQ, led by Jurgi Camblong, with a market cap of $322.3M. As of Q3 2025, 26% of shares are held by 39 institutional investors, with GENERATION INVESTMENT MANAGEMENT LLP as the largest holder at 10.05%.
Overview of institutional ownership in SOPH as of Q3 2025 with a market cap of $321.7M
Based on market cap of $321.7M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Institutions with the largest positions in SOPH as of Q3 2025
| Institution | Position Value |
|---|---|
G GENERATION INVESTMENT MANAGEMENT LLP Institution | $32.3M 0.21% of portfolio |
AKRE CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy | $17.7M 0.18% of portfolio |
B BANQUE PICTET & CIE SA Institution | $10.5M 0.11% of portfolio |
Alta Wealth Advisors LLC RIA/Wealth | $6.7M 2.40% of portfolio |
PRINCIPAL FINANCIAL GROUP INC Institution | $6.6M 0.00% of portfolio |
Archon Capital Management LLC Hedge Fund•Long/Short | $2.0M 1.21% of portfolio |
P Pictet & Cie SA Institution | $1.2M 0.02% of portfolio |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $1.1M 0.00% of portfolio |
FEDERATED INVESTORS INC /PA/ Long Only Manager | $999.6K 0.00% of portfolio |
E EDMOND DE ROTHSCHILD HOLDING S.A. Institution | $967.9K 0.01% of portfolio |
Institutional buying and selling activity for SOPH in Q3 2025
| Institution | Net Bought |
|---|---|
Alta Wealth Advisors LLC RIA/Wealth | +$6.7M +1.4M shares |
Archon Capital Management LLC Hedge Fund•Long/Short | +$502.4K +105.5K shares |
THOMPSON SIEGEL & WALMSLEY LLC Long Only Manager | +$141.8K +29.8K shares |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | +$88.0K +18.5K shares |
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant | +$59.3K +12.5K shares |
S Squarepoint Ops LLC Hedge Fund•Quant | +$48.7K +10.2K shares |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | +$48.1K +10.1K shares |
Savvy Advisors, Inc. RIA/Wealth | +$47.6K +10.0K shares |
GOLDMAN SACHS GROUP INC Institution | +$42.0K +8.8K shares |
UBS Group AG Institution | +$40.1K +8.4K shares |
| Institution | Net Sold |
|---|---|
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$1.7M −358.5K shares |
E Ensign Peak Advisors, Inc Institution | −$260.7K −54.8K shares |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | −$127.5K −26.8K shares |
Ridgewood Investments LLC RIA/Wealth | −$106.8K −34.4K shares |
FEDERATED INVESTORS INC /PA/ Long Only Manager | −$47.6K −10.0K shares |
PRINCIPAL FINANCIAL GROUP INC Institution | −$42.6K −9.0K shares |
Pathstone Holdings, LLC Family Office | −$18.4K −3.9K shares |
Green Alpha Advisors, LLC Long Only Manager | −$8.0K −1.7K shares |
CITIGROUP INC Institution | −$4.3K −1.4K shares |
JPMORGAN CHASE & CO Institution | −$614.0 −198.0 shares |
Institutions that initiated new positions or completely exited SOPH in Q3 2025
| Institution | Position Value |
|---|---|
THOMPSON SIEGEL & WALMSLEY LLC Long Only Manager | $141.8K 29.8K shares |
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant | $59.3K 12.5K shares |
Savvy Advisors, Inc. RIA/Wealth | $47.6K 10.0K shares |
Groupe la Francaise Fund of Funds | $569.0 120.0 shares |
S SBI Securities Co., Ltd. Institution | $5.0 1.0 shares |
| Institution | Previous Position |
|---|---|
Ridgewood Investments LLC RIA/Wealth | $106.8K 34.4K shares |
CITIGROUP INC Institution | $4.3K 1.4K shares |
JPMORGAN CHASE & CO Institution | $614.0 198.0 shares |
Institutions with the largest Call and Put options positions in SOPH as of Q3 2025
| Institution | Position Value |
|---|---|
| No call positions found | |
| Institution | Position Value |
|---|---|
| No put positions found | |
Institutions with SOPH as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
Alta Wealth Advisors LLC RIA/Wealth | 2.40% $6.7M |
Archon Capital Management LLC Hedge Fund•Long/Short | 1.21% $2.0M |
G GENERATION INVESTMENT MANAGEMENT LLP Institution | 0.21% $32.3M |
Green Alpha Advisors, LLC Long Only Manager | 0.19% $196.2K |
AKRE CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy | 0.18% $17.7M |
S | 0.14% $222.4K |
B BANQUE PICTET & CIE SA Institution | 0.11% $10.5M |
P Pictet & Cie SA Institution | 0.02% $1.2M |
E EDMOND DE ROTHSCHILD HOLDING S.A. Institution | 0.01% $967.9K |
GSA CAPITAL PARTNERS LLP Hedge Fund•Quant | 0.01% $59.3K |
Discover hedge funds investing in SOPH

| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
ETF ETF | $5.0B | 4.11% | |
Semiconductors Technology | $3.4B | 2.80% | |
Consumer Electronics Technology | $1.8B | 1.46% |
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