Tiziana Life Sciences

TLSA • NASDAQ

Tiziana Life Sciences is a biotechnology company in the healthcare sector on NASDAQ, led by Ivor Elrifi, with a market cap of $211.5M. As of Q3 2025, 3% of shares are held by 30 institutional investors, with Dauntless Investment Group, LLC as the largest holder at 2.34%.

Chief Executive OfficerIvor Elrifi

Market Cap$211.5M

Biotechnology

Healthcare

Employees9.0

Websitetizianalifesciences.com

Overview

Overview of institutional ownership in TLSA as of Q3 2025 with a market cap of $252.4M

All Institutions

Institutions: 30
Value Held: $8.7M
Shares Held: 4.0M
Avg Position: $289.4K
Median Position: $42.6K

Hedge Funds

Hedge Funds: 1
Value Held: $520.2K
Shares Held: 240.8K
Avg Position: $520.2K
Median Position: $520.2K

Ownership Breakdown

Institutional (non-HF)

3.23%

$8.2M

Hedge Funds

0.206%

$520.2K

Retail & Other

96.56%

$243.7M

Based on market cap of $252.4M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in TLSA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
D Dauntless Investment Group, LLC Institution	-	$5.9M 15.52% of portfolio	2.34% 2.7M shares	Q1 2025 Held for 8 months	$38.1M
Marshall Wace LLP Institution	Diana Lj Harrison President	$578.9K 0.00% of portfolio	0.23% 268.0K shares	Q2 2025 Held for 5 months	$90.3B
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$520.2K 0.00% of portfolio	0.21% 240.8K shares	Q3 2025 Held for 2 months	$121.98B
MORGAN STANLEY RIA/Wealth	Jed Finn CEO	$209.7K 0.00% of portfolio	0.08% 97.1K shares	Q2 2020 Held for 5y 5m	$1.65T
Zhang Financial LLC RIA/Wealth	Lynn Ling Chen-Zhang CEO	$181.9K 0.01% of portfolio	0.07% 84.2K shares	Q2 2022 Held for 3y 5m	$2.5B
Kovitz Investment Group Partners, LLC RIA/Wealth	Mitchell Armin Kovitz CEO	$171.4K 0.00% of portfolio	0.07% 79.4K shares	Q3 2024 Held for 1y 2m	$25.6B
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$168.9K 0.00% of portfolio	0.07% 78.2K shares	Q1 2021 Held for 4y 8m	$1.57T
H HSBC HOLDINGS PLC Institution	-	$159.8K 0.00% of portfolio	0.06% 75.4K shares	Q4 2021 Held for 3y 11m	$169.01B
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	-	$132.9K 0.00% of portfolio	0.05% 61.5K shares	Q1 2025 Held for 8 months	$67.9B
EWA, LLC RIA/Wealth	Matthew Bishop Blocki Managing Partner	$99.5K 0.03% of portfolio	0.04% 46.1K shares	Q3 2023 Held for 2y 2m	$354.1M

Net Capital Flow

Institutional buying and selling activity for TLSA in Q3 2025

Traded: −$918.1K
Buyers: 13
Sellers: 14
Total Bought: +$1.4M
Total Sold: −$2.3M
Avg Position: $241.2K

Biggest Buyers

Institution	Net Bought	Current Position
Marshall Wace LLP Institution	+$526.3K +243.6K shares	$578.9K 268.0K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$520.2K +240.8K shares	$520.2K 240.8K shares
Q Quadrature Capital Ltd Institution	+$80.8K +37.4K shares	$80.8K 37.4K shares
SCHMEIDLER A R & CO INC RIA/Wealth	+$66.3K +30.7K shares	$66.3K 30.7K shares
MORGAN STANLEY RIA/Wealth	+$51.5K +23.8K shares	$209.7K 97.1K shares
GOLDMAN SACHS GROUP INC Institution	+$46.4K +21.5K shares	$46.4K 21.5K shares
UBS Group AG Institution	+$41.8K +19.3K shares	$51.0K 23.6K shares
$US BANCORP \DE\ logo$ US BANCORP \DE\ Institution	+$21.9K +10.2K shares	$21.9K 10.2K shares
C CI Private Wealth, LLC RIA/Wealth	+$4.4K +2.1K shares	$26.4K 12.2K shares
A Advisor Group Holdings, Inc. Institution	+$2.1K +1.0K shares	$34.6K 16.3K shares

Biggest Sellers

Institution	Net Sold	Current Position
D Dauntless Investment Group, LLC Institution	−$1.5M −682.7K shares	$5.9M 2.7M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$314.4K −199.0K shares	Sold Off 0 shares
H HRT FINANCIAL LLC Institution	−$132.9K −84.1K shares	Sold Off 0 shares
S SIMPLEX TRADING, LLC Institution	−$106.3K −67.3K shares	Sold Off 0 shares
H HSBC HOLDINGS PLC Institution	−$63.6K −30.0K shares	$159.8K 75.4K shares
Armis Advisers, LLC RIA/Wealth	−$63.3K −42.8K shares	Sold Off 0 shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	−$53.0K −24.6K shares	$132.9K 61.5K shares
T TWO SIGMA SECURITIES, LLC Institution	−$27.6K −17.5K shares	Sold Off 0 shares
J JANE STREET GROUP, LLC Institution	−$15.1K −7.0K shares	$38.9K 18.0K shares
Caitlin John, LLC RIA/Wealth	−$14.0K −6.5K shares	$7.6K 3.5K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited TLSA in Q3 2025

New Positions: 3
New Value: $148.4K
Exited Positions: 6
Exited Value: $645.3K

New Positions

Institution	Position Value
Q Quadrature Capital Ltd Institution	$80.8K 37.4K shares
SCHMEIDLER A R & CO INC RIA/Wealth	$66.3K 30.7K shares
J JONES FINANCIAL COMPANIES LLLP Institution	$1.3K 650.0 shares

Exited Positions

Institution	Previous Position
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$314.4K 199.0K shares
H HRT FINANCIAL LLC Institution	$132.9K 84.1K shares
S SIMPLEX TRADING, LLC Institution	$106.3K 67.3K shares
Armis Advisers, LLC RIA/Wealth	$63.3K 42.8K shares
T TWO SIGMA SECURITIES, LLC Institution	$27.6K 17.5K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	$790.0 500.0 shares

Options Activity

Institutions with the largest Call and Put options positions in TLSA as of Q3 2025

Call Positions: 1
Call Value: $69.1K
Put Positions: 0
Put Value: -

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$69.1K 320.0 contracts

Put Positions

Institution	Position Value
No put positions found

Most Committed Institutions

Institutions with TLSA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
D Dauntless Investment Group, LLC Institution	-	15.52% $5.9M	2.34% 2.7M shares	Q1 2025 Held for 8 months	$38.1M
EWA, LLC RIA/Wealth	Matthew Bishop Blocki Managing Partner	0.03% $99.5K	0.04% 46.1K shares	Q3 2023 Held for 2y 2m	$354.1M
Zhang Financial LLC RIA/Wealth	Lynn Ling Chen-Zhang CEO	0.01% $181.9K	0.07% 84.2K shares	Q2 2022 Held for 3y 5m	$2.5B
Caitlin John, LLC RIA/Wealth	Ronald John Briggs Owner	0.01% $7.6K	0.00% 3.5K shares	Q3 2024 Held for 1y 2m	$143.4M
SCHMEIDLER A R & CO INC RIA/Wealth	Stephen Robert Burke Managing Partner	0.00% $66.3K	0.03% 30.7K shares	Q3 2025 Held for 2 months	$1.3B
JNBA Financial Advisors RIA/Wealth	Richard Stephen Brown Chairman	0.00% $25.9K	0.01% 12.0K shares	Q1 2023 Held for 2y 8m	$1.1B
W Wealth Alliance Institution	-	0.00% $22.2K	0.01% 10.3K shares	Q1 2025 Held for 8 months	$960.9M
Q Quadrature Capital Ltd Institution	-	0.00% $80.8K	0.03% 37.4K shares	Q3 2025 Held for 2 months	$8.5B
Venture Visionary Partners LLC RIA/Wealth	Craig Douglas Findley CEO	0.00% $21.6K	0.01% 10.0K shares	Q3 2024 Held for 1y 2m	$2.9B
Kovitz Investment Group Partners, LLC RIA/Wealth	Mitchell Armin Kovitz CEO	0.00% $171.4K	0.07% 79.4K shares	Q3 2024 Held for 1y 2m	$25.6B