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5AM Venture Management, LLC
5AM Venture Management, LLC is an institution, managing $273.0M across 25 long positions as of Q3 2025 with 81% Healthcare concentration and 70% concentrated in top 10 holdings.
- Portfolio Value
- $273.0M
- Positions
- 25
- Top Holding
- SKYE at 13.94%
- Last Reported
- Q3 2025
Top Holdings
Largest long holdings in 5AM Venture Management, LLC's portfolio (69.9% of total portfolio)
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| Holding | Sector | Position | Weight | Traded | Ownership |
|---|---|---|---|---|---|
Biotechnology Healthcare | $38.0M | 13.94% | -$909.4K Sold | — 9.7M shares | |
Biotechnology Healthcare | $24.7M | 9.04% | -$301.6K Sold | 11.19% 4.3M shares | |
Biotechnology Healthcare | $19.9M | 7.29% | — | 1.24% 797.6K shares | |
Unknown Unknown | $17.6M | 6.45% | +$8.8M Bought | 29.11% 5.9M shares | |
Unknown Unknown | $16.5M | 6.05% | -$3.6M Sold | — 680.9K shares | |
Biotechnology Healthcare | $15.9M | 5.82% | — | 0.90% 736.6K shares | |
Biotechnology Healthcare | $15.8M | 5.79% | — | 1.30% 772.5K shares | |
Biotechnology Healthcare | $15.0M | 5.48% | — | 1.52% 1.1M shares | |
Biotechnology Healthcare | $14.4M | 5.26% | -$24.4M Sold | 0.92% 365.1K shares | |
Biotechnology Healthcare | $13.1M | 4.81% | — | 1.76% 939.3K shares |
Changes
Portfolio activity, position movements, and quarter-over-quarter changes in 5AM Venture Management, LLC's latest filing
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Market Value
Q/Q Change
Net Flows % of MV
Turnover Ratio
New Purchases
Added To
Sold Out Of
Reduced Holdings
Increased Positions
| Position | Shares Δ |
|---|---|
+100.45% |
Decreased Positions
| Position | Shares Δ |
|---|---|
Sold | |
Sold | |
Sold | |
Sold | |
-62.93% |
Analytics
Portfolio insights and performance metrics for 5AM Venture Management, LLC
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