Skye Bioscience
SKYE • NASDAQ
Skye Bioscience is a biotechnology company in the healthcare sector on NASDAQ, led by Punit Dhillon, with a market cap of $121.2M. As of Q3 2025, 64% of shares are held by 56 institutional investors, with 5AM Venture Management, LLC as the largest holder at -.
CEOPunit Dhillon
Market Cap$121.2M
Biotechnology
Healthcare
Employees11.0
Websiteskyebioscience.com
Country
United States of America
Overview
Overview of institutional ownership in SKYE as of Q3 2025 with a market cap of $121.2M
All Institutions
- Institutions
- 56
- Value Held
- $78.1M
- Shares Held
- 19.9M
- Avg Position
- $1.4M
- Median Position
- $65.1K
Hedge Funds
- Hedge Funds
- 7
- Value Held
- $16.7M
- Shares Held
- 4.2M
- Avg Position
- $2.4M
- Median Position
- $1.8M
Ownership Breakdown
Based on market cap of $121.2M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in SKYE as of Q3 2025
| Institution | Position Value |
|---|---|
5 5AM Venture Management, LLC Institution | $38.0M 13.94% of portfolio |
V Versant Venture Management, LLC Institution | $7.9M 3.71% of portfolio |
B BAKER BROS. ADVISORS LP Hedge Fund•Sector | $5.7M 0.05% of portfolio |
 Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy | $4.7M 0.03% of portfolio |
 VANGUARD GROUP INC Institution | $3.5M 0.00% of portfolio |
E Ensign Peak Advisors, Inc Institution | $3.0M 0.00% of portfolio |
 DRIEHAUS CAPITAL MANAGEMENT LLC Hedge Fund•Event Driven | $2.4M 0.02% of portfolio |
S SPHERA FUNDS MANAGEMENT LTD. Institution | $1.9M 0.45% of portfolio |
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy | $1.8M 0.01% of portfolio |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $1.6M 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for SKYE in Q3 2025
- Traded
- −$2.1M
- Buyers
- 22
- Sellers
- 31
- Total Bought
- +$2.0M
- Total Sold
- −$4.1M
- Avg Position
- $1.1M
Biggest Buyers
| Institution | Net Bought |
|---|---|
 Marshall Wace LLP Institution | +$578.9K +147.3K shares |
 BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | +$417.6K +106.3K shares |
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy | +$351.1K +89.4K shares |
VANGUARD GROUP INC Institution | +$176.2K +44.8K shares |
 TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | +$114.6K +29.2K shares |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | +$113.4K +28.9K shares |
Q Quadrature Capital Ltd Institution | +$64.8K +16.4K shares |
 DIMENSIONAL FUND ADVISORS LP Long Only Manager | +$52.7K +13.4K shares |
J JANE STREET GROUP, LLC Institution | +$50.1K +12.7K shares |
C CAPITAL ADVISORS INC/OK Institution | +$39.3K +10.0K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
5 5AM Venture Management, LLC Institution | −$909.4K −231.4K shares |
F FRED ALGER MANAGEMENT INC Long Only Manager | −$842.1K −201.5K shares |
B BlackRock, Inc. Institution | −$521.7K −132.8K shares |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$268.6K −68.4K shares |
 PLATINUM INVESTMENT MANAGEMENT LTD Long Only Manager | −$236.7K −60.2K shares |
S SPHERA FUNDS MANAGEMENT LTD. Institution | −$233.9K −59.5K shares |
L LPL Financial LLC Institution | −$202.7K −51.6K shares |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | −$176.8K −45.0K shares |
Q Qube Research & Technologies Ltd Institution | −$139.7K −35.5K shares |
 AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$121.8K −29.1K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited SKYE in Q3 2025
- New Positions
- 10
- New Value
- $584.6K
- Exited Positions
- 13
- Exited Value
- $1.2M
New Positions
| Institution | Position Value |
|---|---|
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | $417.6K 106.3K shares |
Q Quadrature Capital Ltd Institution | $64.8K 16.4K shares |
DIMENSIONAL FUND ADVISORS LP Long Only Manager | $52.7K 13.4K shares |
C CAPITAL ADVISORS INC/OK Institution | $39.3K 10.0K shares |
G GROUP ONE TRADING, L.P. Institution | $9.5K 2.4K shares |
 Fortitude Family Office, LLC Family Office | $448.0 114.0 shares |
 Rockefeller Capital Management L.P. Long Only Manager | $153.0 39.0 shares |
O Optiver Holding B.V. Institution | $79.0 20.0 shares |
 Groupe la Francaise Fund of Funds | $46.0 14.0 shares |
 SRS Capital Advisors, Inc. RIA/Wealth | $35.0 9.0 shares |
Exited Positions
| Institution | Previous Position |
|---|---|
F FRED ALGER MANAGEMENT INC Long Only Manager | $842.1K 201.5K shares |
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy | $121.8K 29.1K shares |
H HRT FINANCIAL LLC Institution | $83.8K 20.0K shares |
 Jain Global LLC Hedge Fund•Multi-Strategy | $83.0K 19.9K shares |
M Millington Financial Advisors, LLC RIA/Wealth | $43.6K 10.0K shares |
Y Y-Intercept Ltd Institution | $42.0K 10.0K shares |
S SIMPLEX TRADING, LLC Institution | $4.9K 1.2K shares |
 FEDERATED INVESTORS INC /PA/ Long Only Manager | $823.0 197.0 shares |
 RAYMOND JAMES FINANCIAL INC RIA/Wealth | $785.0 188.0 shares |
E EverSource Wealth Advisors, LLC RIA/Wealth | $606.0 145.0 shares |
Options Activity
Institutions with the largest Call and Put options positions in SKYE as of Q3 2025
- Call Positions
- 7
- Call Value
- $2.1M
- Put Positions
- 2
- Put Value
- $90.0K
Call Positions
| Institution | Position Value |
|---|---|
 DIADEMA PARTNERS LP Hedge Fund•Long/Short | $1.2M 3.0K contracts |
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy | $393.0K 1.0K contracts |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $167.0K 425.0 contracts |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $113.2K 288.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $110.8K 282.0 contracts |
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | $104.5K 266.0 contracts |
J JANE STREET GROUP, LLC Institution | $59.3K 151.0 contracts |
Put Positions
| Institution | Position Value |
|---|---|
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $90.0K 229.0 contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | - - contracts |
Most Committed Institutions
Institutions with SKYE as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
5 5AM Venture Management, LLC Institution | 13.94% $38.0M |
V Versant Venture Management, LLC Institution | 3.71% $7.9M |
S SPHERA FUNDS MANAGEMENT LTD. Institution | 0.45% $1.9M |
PLATINUM INVESTMENT MANAGEMENT LTD Long Only Manager | 0.06% $916.1K |
B BAKER BROS. ADVISORS LP Hedge Fund•Sector | 0.05% $5.7M |
Schonfeld Strategic Advisors LLC Hedge Fund•Multi-Strategy | 0.03% $4.7M |
 Capital Advisors Wealth Management, LLC RIA/Wealth | 0.02% $175.0K |
DRIEHAUS CAPITAL MANAGEMENT LLC Hedge Fund•Event Driven | 0.02% $2.4M |
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | 0.01% $417.6K |
A Alyeska Investment Group, L.P. Hedge Fund•Multi-Strategy | 0.01% $1.8M |
Hedge Fund Spotlight
Discover hedge funds investing in SKYE
DRIEHAUS CAPITAL MANAGEMENT LLC
Hedge Fund • Event Driven
Portfolio ManagerStephen Thomas Weber
- Portfolio Value
- $13.9B
- Positions
- 419
- Last Reported
- Q3 2025
Sector Allocation
Position in Skye Bioscience
- Market Value
- $2.4M
- Shares Held
- 620.4K
- Portfolio Weight
- 0.02%
- Owned Since
- 2024-Q2
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Semiconductors Technology | $626.6M | 4.49% | |
Biotechnology Healthcare | $270.0M | 1.94% | |
Aerospace & Defense Industrials | $186.6M | 1.34% |
