Enliven Therapeutics

ELVN • NASDAQ

Enliven Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by Sam Kintz, M.B.A., with a market cap of $1.0B. As of Q3 2025, 100% of shares are held by 133 institutional investors, with ORBIMED ADVISORS LLC as the largest holder at 13.44%.

President and Chief Executive OfficerSam Kintz, M.B.A.

Market Cap$1.0B

Biotechnology

Healthcare

Employees50.0

Websiteenliventherapeutics.com

Country

United States of America

Overview

Overview of institutional ownership in ELVN as of Q3 2025 with a market cap of $1.2B

All Institutions

Institutions: 133
Value Held: $1.2B
Shares Held: 59.4M
Avg Position: $9.1M
Median Position: $563.3K

Hedge Funds

Hedge Funds: 25
Value Held: $480.3M
Shares Held: 23.5M
Avg Position: $19.2M
Median Position: $4.1M

Ownership Breakdown

Institutional (non-HF)

60.65%

$735.4M

Hedge Funds

39.61%

$480.3M

Retail & Other

Based on market cap of $1.2B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in ELVN as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
ORBIMED ADVISORS LLC Hedge Fund•Sector	Sam Block Iii CFO	$162.9M 3.95% of portfolio	13.44% 8.0M shares	Q4 2022 Held for 2y 11m	$4.1B
FMR LLC Institution	-	$145.9M 0.01% of portfolio	12.04% 7.1M shares	Q4 2022 Held for 2y 11m	$1.92T
COMMODORE CAPITAL LP Hedge Fund•Long/Short	Michael Jonathan Kramarz Managing Partner	$96.1M 4.69% of portfolio	7.92% 4.7M shares	Q1 2023 Held for 2y 8m	$2.0B
Fairmount Funds Management LLC Hedge Fund•Sector	Peter Evan Harwin Managing Partner	$76.0M 6.84% of portfolio	6.27% 3.7M shares	Q4 2022 Held for 2y 11m	$1.1B
B BlackRock, Inc. Institution	-	$72.0M 0.00% of portfolio	5.94% 3.5M shares	Q4 2022 Held for 2y 11m	$5.67T
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	$66.0M 3.72% of portfolio	5.45% 3.2M shares	Q1 2023 Held for 2y 8m	$1.8B
Polar Capital Holdings Plc Long Only Manager	Gavin Mark Rochussen CEO	$63.4M 0.30% of portfolio	5.22% 3.1M shares	Q2 2024 Held for 1y 5m	$20.8B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$52.3M 0.00% of portfolio	4.31% 2.6M shares	Q4 2022 Held for 2y 11m	$6.69T
HENDERSON GROUP PLC Institution	Ali Dibadj CEO	$36.7M 0.02% of portfolio	3.03% 1.8M shares	Q4 2022 Held for 2y 11m	$218.74B
N Novo A/S Institution	-	$29.2M 1.92% of portfolio	2.41% 1.4M shares	Q2 2025 Held for 5 months	$1.5B

Net Capital Flow

Institutional buying and selling activity for ELVN in Q3 2025

Traded: +$44.1K
Buyers: 79
Sellers: 41
Total Bought: +$103.8M
Total Sold: −$103.7M
Avg Position: $8.3M

Biggest Buyers

Institution	Net Bought	Current Position
Vestal Point Capital, LP Hedge Fund•Long/Short	+$18.6M +910.0K shares	$23.7M 1.2M shares
B BlackRock, Inc. Institution	+$11.3M +551.4K shares	$72.0M 3.5M shares
D Duquesne Family Office LLC Institution	+$9.9M +484.4K shares	$19.4M 947.4K shares
Pictet Asset Management Holding SA Long Only Manager	+$8.8M +430.6K shares	$28.6M 1.4M shares
N Novo A/S Institution	+$7.0M +341.8K shares	$29.2M 1.4M shares
F First Turn Management, LLC Hedge Fund•Long/Short	+$5.6M +273.4K shares	$16.0M 783.4K shares
GEODE CAPITAL MANAGEMENT LLC ETF Provider	+$4.1M +202.3K shares	$22.2M 1.1M shares
Candriam Luxembourg S.C.A. Long Only Manager	+$3.9M +192.7K shares	$12.5M 609.4K shares
Partner Fund Management, L.P. Hedge Fund•Sector	+$3.2M +156.5K shares	$3.2M 156.5K shares
STATE STREET CORP Institution	+$3.0M +148.9K shares	$19.8M 965.1K shares

Biggest Sellers

Institution	Net Sold	Current Position
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	−$17.0M −849.0K shares	Sold Off 0 shares
Woodline Partners LP Hedge Fund•Long/Short	−$16.4M −800.2K shares	$6.2M 300.5K shares
VR Adviser, LLC Venture Capital	−$16.4M −800.0K shares	$66.0M 3.2M shares
TCG Crossover Management, LLC Venture Capital	−$10.0M −498.0K shares	Sold Off 0 shares
FMR LLC Institution	−$8.8M −430.7K shares	$145.9M 7.1M shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	−$6.4M −312.7K shares	$21.3M 1.0M shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$6.3M −309.9K shares	$23.8M 1.2M shares
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	−$6.1M −296.9K shares	$4.7M 231.3K shares
Ally Bridge Group LLC Hedge Fund•Sector	−$5.6M −281.4K shares	Sold Off 0 shares
UBS Group AG Institution	−$1.2M −58.8K shares	$1.6M 79.5K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited ELVN in Q3 2025

New Positions: 13
New Value: $5.5M
Exited Positions: 11
Exited Value: $36.3M

New Positions

Institution	Position Value
Partner Fund Management, L.P. Hedge Fund•Sector	$3.2M 156.5K shares
S Squarepoint Ops LLC Hedge Fund•Quant	$733.7K 35.8K shares
Connor, Clark & Lunn Investment Management Ltd. Long Only Manager	$711.9K 34.8K shares
W Winton Capital Group Ltd Institution	$336.9K 16.5K shares
M Man Group plc Institution	$273.7K 13.4K shares
LANDSCAPE CAPITAL MANAGEMENT, L.L.C. Hedge Fund•Market Neutral	$210.9K 10.3K shares
Point72 Europe LLP Digital Asset Manager	$14.6K 712.0 shares
Q QUADRANT CAPITAL GROUP LLC Institution	$6.0K 295.0 shares
ORG Partners LLC RIA/Wealth	$4.6K 225.0 shares
O Optiver Holding B.V. Institution	$2.2K 108.0 shares

Exited Positions

Institution	Previous Position
RA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$17.0M 849.0K shares
TCG Crossover Management, LLC Venture Capital	$10.0M 498.0K shares
Ally Bridge Group LLC Hedge Fund•Sector	$5.6M 281.4K shares
J JANE STREET GROUP, LLC Institution	$1.1M 57.0K shares
Weiss Asset Management LP Hedge Fund•Multi-Strategy	$955.3K 47.6K shares
Aster Capital Management Ltd RIA/Wealth	$573.4K 28.6K shares
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC Hedge Fund•Distressed	$568.4K 28.3K shares
VOLORIDGE INVESTMENT MANAGEMENT, LLC Hedge Fund•Multi-Strategy	$354.2K 17.7K shares
Point72 Ltd RIA/Wealth	$30.8K 1.5K shares
Hanson McClain, Inc. RIA/Wealth	$763.0 38.0 shares

Options Activity

Institutions with the largest Call and Put options positions in ELVN as of Q3 2025

Call Positions: 0
Call Value: -
Put Positions: 1
Put Value: $1.2M

Call Positions

Institution	Position Value
No call positions found

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$1.2M 590.0 contracts

Most Committed Institutions

Institutions with ELVN as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Fairmount Funds Management LLC Hedge Fund•Sector	Peter Evan Harwin Managing Partner	6.84% $76.0M	6.27% 3.7M shares	Q4 2022 Held for 2y 11m	$1.1B
5 5AM Venture Management, LLC Institution	-	5.79% $15.8M	1.30% 772.5K shares	Q1 2023 Held for 2y 8m	$273.0M
COMMODORE CAPITAL LP Hedge Fund•Long/Short	Michael Jonathan Kramarz Managing Partner	4.69% $96.1M	7.92% 4.7M shares	Q1 2023 Held for 2y 8m	$2.0B
ORBIMED ADVISORS LLC Hedge Fund•Sector	Sam Block Iii CFO	3.95% $162.9M	13.44% 8.0M shares	Q4 2022 Held for 2y 11m	$4.1B
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	3.72% $66.0M	5.45% 3.2M shares	Q1 2023 Held for 2y 8m	$1.8B
F First Turn Management, LLC Hedge Fund•Long/Short	Lisa Gable Wheatley Managing Partner	2.41% $16.0M	1.32% 783.4K shares	Q2 2024 Held for 1y 5m	$666.0M
N Novo A/S Institution	-	1.92% $29.2M	2.41% 1.4M shares	Q2 2025 Held for 5 months	$1.5B
Patient Square Capital LP Private Equity	Adam Mark Fliss Founder	1.37% $5.1M	0.42% 250.8K shares	Q3 2024 Held for 1y 2m	$373.9M
HighVista Strategies LLC Fund of Funds	Richard P Vishton CFO	1.28% $5.3M	0.44% 259.1K shares	Q2 2023 Held for 2y 5m	$413.3M
Vestal Point Capital, LP Hedge Fund•Long/Short	Ryan Christopher Wilder CIO	1.20% $23.7M	1.96% 1.2M shares	Q2 2025 Held for 5 months	$2.0B

Hedge Fund Spotlight

Discover hedge funds investing in ELVN

Quantbot Technologies LLC

Hedge Fund • Quant

Portfolio ManagerPaul Edward White

Portfolio Value: $3.7B
Positions: 1,694
Last Reported: Q3 2025

Sector Allocation

Position in Enliven Therapeutics

Market Value: $43.9K
Shares Held: 2.1K
Portfolio Weight: 0.00%
Owned Since: 2025-Q1

Top Holding	Sector	Market Value	Weight
1 SoFi Technologies, Inc. SOFI	Financial - Credit Services Financial Services	$29.1M	0.79%
2 Lam Research LRCX	Semiconductors Technology	$27.8M	0.75%
3 Honeywell International HON	Conglomerates Industrials	$27.6M	0.75%