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Centessa Pharmaceuticals
CNTA • NASDAQ
Centessa Pharmaceuticals is a pharmaceutical preparations company on NASDAQ, led by Mario Alberto Accardi. As of Q3 2025, 118 institutional investors hold shares in this company, with total holdings valued at $3.0B. Medicxi Ventures Management Ltd is the largest holder with a position valued at $484.1M.
CEOMario Alberto Accardi
Overview
Overview of institutional ownership in CNTA as of Q3 2025
All Institutions
- Institutions
- 118
- Value Held
- $3.0B
- Shares Held
- 123.3M
- Avg Position
- $25.3M
- Median Position
- $2.8M
Hedge Funds
- Hedge Funds
- 40
- Value Held
- $713.6M
- Shares Held
- 29.4M
- Avg Position
- $17.8M
- Median Position
- $5.0M
Biggest Investors
Institutions with the largest positions in CNTA as of Q3 2025
| Institution | Position Value |
|---|---|
M Medicxi Ventures Management Ltd Institution | $484.1M 65.03% of portfolio |
 venBio Select Advisor LLC RIA/Wealth | $262.1M 3.39% of portfolio |
A ADAGE CAPITAL PARTNERS GP LLC Institution | $243.3M 0.39% of portfolio |
I Index Venture Life Associates VI Ltd Institution | $241.6M 100.00% of portfolio |
G GENERAL ATLANTIC LLC Institution | $234.8M 7.05% of portfolio |
 FMR LLC Institution | $152.2M 0.01% of portfolio |
 HENDERSON GROUP PLC Institution | $131.1M 0.06% of portfolio |
 FARALLON CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy | $105.0M 0.59% of portfolio |
 First Light Asset Management, LLC Hedge Fund•Sector | $88.2M 8.31% of portfolio |
S Siren, L.L.C. Institution | $78.3M 3.07% of portfolio |
Net Capital Flow
Institutional buying and selling activity for CNTA in Q3 2025
- Traded
- +$324.7M
- Buyers
- 57
- Sellers
- 59
- Total Bought
- +$587.0M
- Total Sold
- −$262.3M
- Avg Position
- $22.0M
Biggest Buyers
| Institution | Net Bought |
|---|---|
venBio Select Advisor LLC RIA/Wealth | +$262.1M +5.8M shares |
FMR LLC Institution | +$59.4M +2.5M shares |
 PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short | +$47.4M +2.0M shares |
 FEDERATED INVESTORS INC /PA/ Long Only Manager | +$42.4M +1.7M shares |
A ADAGE CAPITAL PARTNERS GP LLC Institution | +$39.6M +1.6M shares |
 RTW INVESTMENTS, LLC Hedge Fund•Sector | +$18.5M +761.9K shares |
 EcoR1 Capital, LLC Hedge Fund•Sector | +$13.3M +550.0K shares |
 Logos Global Management LP Hedge Fund•Long/Short | +$12.7M +525.0K shares |
 BANK OF AMERICA CORP /DE/ Institution | +$10.1M +417.2K shares |
 ARMISTICE CAPITAL, LLC Hedge Fund•Long/Short | +$9.2M +-22.0K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy | −$36.8M −1.5M shares |
HENDERSON GROUP PLC Institution | −$27.3M −1.1M shares |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$18.3M −755.6K shares |
 MORGAN STANLEY RIA/Wealth | −$16.2M −669.0K shares |
First Light Asset Management, LLC Hedge Fund•Sector | −$15.9M −657.6K shares |
 StemPoint Capital LP Hedge Fund•Long/Short | −$14.8M −610.3K shares |
 COMMODORE CAPITAL LP Hedge Fund•Long/Short | −$10.9M −448.3K shares |
 BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy | −$10.1M −416.0K shares |
 GOLDMAN SACHS GROUP INC Institution | −$7.6M −311.7K shares |
 Woodline Partners LP Hedge Fund•Long/Short | −$7.1M −292.6K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited CNTA in Q3 2025
- New Positions
- 23
- New Value
- $327.1M
- Exited Positions
- 18
- Exited Value
- $13.6M
New Positions
| Institution | Position Value |
|---|---|
venBio Select Advisor LLC RIA/Wealth | $262.1M 10.8M shares |
FEDERATED INVESTORS INC /PA/ Long Only Manager | $42.4M 1.7M shares |
ARMISTICE CAPITAL, LLC Hedge Fund•Long/Short | $9.2M 378.0K shares |
R ROYCE & ASSOCIATES LLC Institution | $6.0M 247.4K shares |
E Eagle Health Investments LP Hedge Fund•Long/Short | $2.5M 103.1K shares |
 Cinctive Capital Management LP Hedge Fund•Multi-Strategy | $2.2M 92.6K shares |
 Rock Springs Capital Management LP Hedge Fund•Sector | $1.7M 69.2K shares |
 Pictet Asset Management Holding SA Long Only Manager | $336.3K 13.9K shares |
D DnB Asset Management AS Institution | $218.0K 9.0K shares |
P Point72 Asia Pte. Ltd. Institution | $162.2K 6.7K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
Q Qube Research & Technologies Ltd Institution | $4.0M 307.9K shares |
 Ally Bridge Group LLC Hedge Fund•Sector | $3.9M 294.0K shares |
G GREAT POINT PARTNERS LLC Private Equity | $3.0M 225.0K shares |
Y Y-Intercept Ltd Institution | $613.2K 46.7K shares |
 STATE STREET CORP Institution | $603.3K 45.9K shares |
 VOLORIDGE INVESTMENT MANAGEMENT, LLC Hedge Fund•Multi-Strategy | $517.4K 39.4K shares |
X XTX Topco Ltd Institution | $471.7K 35.9K shares |
R Rathbone Brothers plc RIA/Wealth | $216.8K 16.5K shares |
 Engineers Gate Manager LP Hedge Fund•Quant | $149.2K 11.4K shares |
Q Quarry LP Institution | $118.2K 9.0K shares |
Options Activity
Institutions with the largest Call and Put options positions in CNTA as of Q3 2025
- Call Positions
- 10
- Call Value
- $32.8M
- Put Positions
- 8
- Put Value
- $19.1M
Call Positions
| Institution | Position Value |
|---|---|
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $10.4M 4.3K contracts |
 Caption Management, LLC Hedge Fund•Long/Short | $8.0M 3.3K contracts |
 Ikarian Capital, LLC Hedge Fund•Event Driven | $7.5M 3.1K contracts |
 BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds | $2.8M 1.1K contracts |
 UBS Group AG Institution | $1.1M 453.0 contracts |
J JANE STREET GROUP, LLC Institution | $1.0M 420.0 contracts |
StemPoint Capital LP Hedge Fund•Long/Short | $905.6K 1.7K contracts |
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $766.3K 316.0 contracts |
W WOLVERINE TRADING, LLC Institution | $329.4K 135.0 contracts |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | - - contracts |
Put Positions
| Institution | Position Value |
|---|---|
Caption Management, LLC Hedge Fund•Long/Short | $11.5M 4.7K contracts |
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $2.3M 950.0 contracts |
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | $1.9M 777.0 contracts |
J JANE STREET GROUP, LLC Institution | $1.7M 716.0 contracts |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $1.2M 500.0 contracts |
 DLD Asset Management, LP Hedge Fund•Multi-Strategy | $242.5K 100.0 contracts |
W WOLVERINE TRADING, LLC Institution | $226.9K 93.0 contracts |
GOLDMAN SACHS GROUP INC Institution | - - contracts |
Most Committed Institutions
Institutions with CNTA as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
I Index Venture Life Associates VI Ltd Institution | 100.00% $241.6M |
M Medicxi Ventures Management Ltd Institution | 65.03% $484.1M |
 Foresite Capital Management VI LLC Venture Capital | 12.31% $31.9M |
First Light Asset Management, LLC Hedge Fund•Sector | 8.31% $88.2M |
G GENERAL ATLANTIC LLC Institution | 7.05% $234.8M |
5 5AM Venture Management, LLC Institution | 6.05% $16.5M |
S Saturn V Capital Management LLC Hedge Fund•Sector | 3.91% $17.8M |
 TCG Crossover Management, LLC Venture Capital | 3.80% $76.1M |
C Cormorant Asset Management, LLC Hedge Fund•Long/Short | 3.64% $46.7M |
venBio Select Advisor LLC RIA/Wealth | 3.39% $262.1M |
Hedge Fund Spotlight
Discover hedge funds investing in CNTA
Caption Management, LLC
Hedge Fund • Long/Short
Portfolio ManagerWilliam Lamblè Cooper
- Portfolio Value
- $1.7B
- Positions
- 577
- Last Reported
- Q3 2025
Sector Allocation
C
Position in Centessa Pharmaceuticals
- Market Value
- $3.0M
- Shares Held
- 125.3K
- Portfolio Weight
- 0.18%
- Owned Since
- 2025-Q1
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Auto - Manufacturers Consumer Cyclical | $155.7M | 9.09% | |
Specialty Retail Consumer Cyclical | $126.3M | 7.37% | |
Semiconductors Technology | $93.3M | 5.45% |
