Entrada Therapeutics

TRDA • NASDAQ

Entrada Therapeutics is a biotechnology company in the healthcare sector on NASDAQ, led by Nathan J. Dowden, with a market cap of $423.5M. As of Q3 2025, 76% of shares are held by 115 institutional investors, with BAKER BROS. ADVISORS LP as the largest holder at 12.79%.

Chief Executive OfficerNathan J. Dowden

Market Cap$423.5M

Biotechnology

Healthcare

Employees159.0

Websiteentradatx.com

Country

United States of America

Overview

Overview of institutional ownership in TRDA as of Q3 2025 with a market cap of $220.6M

All Institutions

Institutions: 115
Value Held: $168.7M
Shares Held: 28.5M
Avg Position: $1.5M
Median Position: $169.1K

Hedge Funds

Hedge Funds: 20
Value Held: $45.1M
Shares Held: 7.8M
Avg Position: $2.3M
Median Position: $439.1K

Ownership Breakdown

Institutional (non-HF)

55.99%

$123.5M

Hedge Funds

20.47%

$45.1M

Retail & Other

23.54%

$51.9M

Based on market cap of $220.6M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in TRDA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	$28.2M 0.26% of portfolio	12.79% 4.9M shares	Q4 2021 Held for 3y 11m	$10.8B
MPM ASSET MANAGEMENT LLC Venture Capital	Ansbert Karl Gadicke Managing Partner	$25.4M 57.09% of portfolio	11.52% 4.4M shares	Q4 2021 Held for 3y 11m	$44.5M
5 5AM Venture Management, LLC Institution	-	$24.7M 9.04% of portfolio	11.19% 4.3M shares	Q4 2021 Held for 3y 11m	$273.0M
B BlackRock, Inc. Institution	-	$11.9M 0.00% of portfolio	5.37% 2.0M shares	Q4 2021 Held for 3y 11m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$9.3M 0.00% of portfolio	4.22% 1.6M shares	Q4 2021 Held for 3y 11m	$6.69T
WELLINGTON MANAGEMENT CO LLP Long Only Manager	Jean Marie Hynes CEO	$5.5M 0.00% of portfolio	2.51% 954.4K shares	Q4 2021 Held for 3y 11m	$571.21B
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$4.9M 0.00% of portfolio	2.20% 836.6K shares	Q4 2021 Held for 3y 11m	$121.98B
StepStone Group LP Fund of Funds	Scott William Hart CEO	$4.4M 2.30% of portfolio	2.00% 761.3K shares	Q4 2021 Held for 3y 11m	$191.8M
C CANTOR FITZGERALD, L. P. Institution	-	$3.9M 0.08% of portfolio	0.18% 67.3K shares	Q3 2025 Held for 2 months	$5.1B
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$3.7M 0.00% of portfolio	1.70% 645.1K shares	Q4 2021 Held for 3y 11m	$1.57T

Net Capital Flow

Institutional buying and selling activity for TRDA in Q3 2025

Traded: −$956.0K
Buyers: 78
Sellers: 40
Total Bought: +$26.9M
Total Sold: −$27.8M
Avg Position: $1.3M

Biggest Buyers

Institution	Net Bought	Current Position
C CANTOR FITZGERALD, L. P. Institution	+$3.9M +67.3K shares	$3.9M 67.3K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$3.9M +666.3K shares	$4.9M 836.6K shares
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	+$1.5M +252.1K shares	$1.7M 297.9K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	+$1.4M +235.4K shares	$1.9M 335.7K shares
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	+$1.2M +214.8K shares	$3.4M 594.3K shares
J JANE STREET GROUP, LLC Institution	+$1.1M +196.4K shares	$1.4M 247.5K shares
MORGAN STANLEY RIA/Wealth	+$1.1M +183.7K shares	$2.0M 346.8K shares
Q Qube Research & Technologies Ltd Institution	+$894.0K +154.1K shares	$1.7M 287.9K shares
B BNP PARIBAS ARBITRAGE, SA Institution	+$842.0K +145.2K shares	$859.6K 148.2K shares
GOLDMAN SACHS GROUP INC Institution	+$801.5K +138.2K shares	$1.3M 222.3K shares

Biggest Sellers

Institution	Net Sold	Current Position
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	−$12.8M −2.2M shares	$2.1M 360.5K shares
HENDERSON GROUP PLC Institution	−$10.2M −1.5M shares	Sold Off 0 shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	−$685.5K −102.0K shares	Sold Off 0 shares
WELLINGTON MANAGEMENT CO LLP Long Only Manager	−$616.5K −106.3K shares	$5.5M 954.4K shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Long Only Manager	−$587.2K −87.4K shares	Sold Off 0 shares
FIRST TRUST ADVISORS LP ETF Provider	−$504.8K −75.1K shares	Sold Off 0 shares
5 5AM Venture Management, LLC Institution	−$301.6K −52.0K shares	$24.7M 4.3M shares
NORTHERN TRUST CORP Institution	−$270.9K −46.7K shares	$1.5M 253.6K shares
Quest Partners LLC Hedge Fund•Quant Macro	−$192.3K −33.2K shares	$37.6K 6.5K shares
PRUDENTIAL FINANCIAL INC Institution	−$190.4K −28.3K shares	Sold Off 0 shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited TRDA in Q3 2025

New Positions: 19
New Value: $7.4M
Exited Positions: 16
Exited Value: $12.8M

New Positions

Institution	Position Value
C CANTOR FITZGERALD, L. P. Institution	$3.9M 67.3K shares
ALGERT COLDIRON INVESTORS LLC Hedge Fund•Quant	$752.9K 129.8K shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	$540.5K 93.2K shares
D D. E. Shaw & Co., Inc. Institution	$415.0K 71.5K shares
TWO SIGMA ADVISERS, LLC Hedge Fund•Multi-Strategy	$298.7K 51.5K shares
GREAT LAKES ADVISORS, LLC Long Only Manager	$238.0K 41.0K shares
B BRIDGEWAY CAPITAL MANAGEMENT INC Long Only Manager	$232.0K 40.0K shares
Atom Investors LP Hedge Fund•Market Neutral	$178.7K 30.8K shares
O OXFORD ASSET MANAGEMENT Institution	$169.1K 29.2K shares
SPRINGBOK CAPITAL MANAGEMENT, LLC Fund of Funds	$149.4K 25.8K shares

Exited Positions

Institution	Previous Position
HENDERSON GROUP PLC Institution	$10.2M 1.5M shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	$685.5K 102.0K shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Long Only Manager	$587.2K 87.4K shares
FIRST TRUST ADVISORS LP ETF Provider	$504.8K 75.1K shares
PRUDENTIAL FINANCIAL INC Institution	$190.4K 28.3K shares
D Dynamic Technology Lab Private Ltd Institution	$166.2K 24.7K shares
M Man Group plc Institution	$112.9K 16.8K shares
ExodusPoint Capital Management, LP Hedge Fund•Multi-Strategy	$106.1K 15.8K shares
HARBOR CAPITAL ADVISORS, INC. ETF Provider	$102.7K 15.3K shares
S Squarepoint Ops LLC Hedge Fund•Quant	$75.3K 11.2K shares

Options Activity

Institutions with the largest Call and Put options positions in TRDA as of Q3 2025

Call Positions: 1
Call Value: $79.5K
Put Positions: 1
Put Value: $81.2K

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$79.5K 137.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$81.2K 140.0 contracts

Most Committed Institutions

Institutions with TRDA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
MPM ASSET MANAGEMENT LLC Venture Capital	Ansbert Karl Gadicke Managing Partner	57.09% $25.4M	11.52% 4.4M shares	Q4 2021 Held for 3y 11m	$44.5M
5 5AM Venture Management, LLC Institution	-	9.04% $24.7M	11.19% 4.3M shares	Q4 2021 Held for 3y 11m	$273.0M
StepStone Group LP Fund of Funds	Scott William Hart CEO	2.30% $4.4M	2.00% 761.3K shares	Q4 2021 Held for 3y 11m	$191.8M
C Corton Capital Inc. Institution	-	0.56% $225.3K	0.10% 38.8K shares	Q2 2025 Held for 5 months	$40.6M
N Nan Fung Group Holdings Ltd Institution	-	0.52% $284.7K	0.13% 49.1K shares	Q1 2022 Held for 3y 8m	$54.3M
B BAKER BROS. ADVISORS LP Hedge Fund•Sector	Scott Lawrence Lessing President	0.26% $28.2M	12.79% 4.9M shares	Q4 2021 Held for 3y 11m	$10.8B
TCG Crossover Management, LLC Venture Capital	Chen Ming Yu Managing Partner	0.17% $3.4M	1.54% 585.0K shares	Q4 2021 Held for 3y 11m	$2.0B
C CANTOR FITZGERALD, L. P. Institution	-	0.08% $3.9M	0.18% 67.3K shares	Q3 2025 Held for 2 months	$5.1B
O OXFORD ASSET MANAGEMENT Institution	Henry Stuart Gibson President	0.06% $169.1K	0.08% 29.2K shares	Q3 2025 Held for 2 months	$272.4M
S SHERBROOKE PARK ADVISERS LLC Hedge Fund•Quant	Kun Gao Founder	0.05% $107.7K	0.05% 18.6K shares	Q3 2025 Held for 2 months	$215.3M

Hedge Fund Spotlight

Discover hedge funds investing in TRDA

TWO SIGMA ADVISERS, LLC

Hedge Fund • Multi-Strategy

Portfolio ManagerScott David Hoffman

Portfolio Value: $50.0B
Positions: 2,312
Last Reported: Q3 2025

Sector Allocation

Position in Entrada Therapeutics

Market Value: $298.7K
Shares Held: 51.5K
Portfolio Weight: 0.00%
Owned Since: 2025-Q3

Top Holding	Sector	Market Value	Weight
1 Nvidia NVDA	Semiconductors Technology	$1.5B	3.07%
2 Microsoft MSFT	Software - Infrastructure Technology	$1.5B	3.03%
3 Apple AAPL	Consumer Electronics Technology	$1.4B	2.79%