Sio Capital Management, LLC Portfolio Holdings
Q3 2025•51 long positions•$395.2M portfolio value
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Holding63 | Sector | Position↕ | Traded↕ | Ownership↕ | Shares Δ↕ | Shares Δ % | Market Cap↕ | Owned Since↕ |
|---|---|---|---|---|---|---|---|---|
Specialty Business Services Industrials | $50.9M 12.89% | +$870.7K Bought | 0.99% 557.6K shares | 548.1K → 557.6K +$870.7K | +1.74% | $5.1B Mid Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $38.9M 9.83% | +$38.9M New | 1.85% 786.5K shares | 0 → 786.5K +$38.9M | New | $2.1B Mid Cap | Q3 2025 Held for 2 months | |
Unknown Unknown | $26.6M 6.72% | +$17.7M Bought | — 562.7K shares | 187.5K → 562.7K +$17.7M | +200.11% | — — | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $22.7M 5.75% | +$13.4M Bought | 1.45% 577.8K shares | 236.1K → 577.8K +$13.4M | +144.74% | $1.6B Small Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $20.2M 5.12% | +$20.2M Bought | 0.409% 674.8K shares | — | — | $5.0B Mid Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $18.8M 4.76% | — | 0.819% 284.8K shares | — | — | $2.3B Mid Cap | Q2 2024 Held for 1y 5m | |
Drug Manufacturers - General Healthcare | $14.9M 3.77% | +$281.1K Bought | 0.007% 177.3K shares | 174.0K → 177.3K +$281.1K | +1.93% | $209.64B Mega Cap | Q1 2025 Held for 8 months | |
Medical - Distribution Healthcare | $14.5M 3.68% | +$14.5M New | 0.181% 219.2K shares | 0 → 219.2K +$14.5M | New | $8.0B Mid Cap | Q3 2025 Held for 2 months | |
Medical - Healthcare Plans Healthcare | $13.8M 3.5% | +$4.5M Bought | 0.079% 387.6K shares | 262.5K → 387.6K +$4.5M | +47.66% | $17.5B Large Cap | Q2 2025 Held for 5 months | |
Household & Personal Products Consumer Defensive | $13.7M 3.47% | +$13.7M Bought | 0.044% 844.0K shares | — | — | $31.1B Large Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $12.2M 3.09% | — | 0.117% 225.1K shares | — | — | $10.4B Large Cap | Q1 2025 Held for 8 months | |
Unknown Unknown | $11.6M 2.94% | +$11.6M Bought | — 268.9K shares | — | — | — — | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $11.6M 2.93% | -$19.5M Sold | 2.69% 190.8K shares | 512.3K → 190.8K −$19.5M | -62.77% | $430.0M Small Cap | Q4 2024 Held for 11 months | |
Medical - Instruments & Supplies Healthcare | $9.7M 2.44% | +$9.7M Bought | 0.411% 198.0K shares | — | — | $2.3B Mid Cap | Q1 2025 Held for 8 months | |
Drug Manufacturers - Specialty & Generic Healthcare | $8.4M 2.12% | +$3.1M Bought | 1.24% 1.5M shares | 947.5K → 1.5M +$3.1M | +58.11% | $676.2M Small Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $8.3M 2.11% | +$8.3M New | 1.35% 683.8K shares | 0 → 683.8K +$8.3M | New | $615.4M Small Cap | Q3 2025 Held for 2 months | |
Unknown Unknown | $8.0M 2.02% | -$298.9K Sold | 4.92% 1.8M shares | 1.8M → 1.8M −$298.9K | -3.61% | $162.3M Micro Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $7.3M 1.84% | +$7.3M New | 0.186% 174.8K shares | 0 → 174.8K +$7.3M | New | $3.9B Mid Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $7.2M 1.82% | -$4.1M Sold | 0.966% 514.9K shares | 810.3K → 514.9K −$4.1M | -36.45% | $745.6M Small Cap | Q1 2024 Held for 1y 8m | |
Unknown Unknown | $5.5M 1.39% | +$5.5M New | 0.402% 185.3K shares | 0 → 185.3K +$5.5M | New | $1.4B Small Cap | Q3 2025 Held for 2 months | |
Medical - Instruments & Supplies Healthcare | $5.3M 1.35% | +$5.3M New | 0.37% 413.8K shares | 0 → 413.8K +$5.3M | New | $1.4B Small Cap | Q3 2025 Held for 2 months | |
Drug Manufacturers - Specialty & Generic Healthcare | $5.1M 1.29% | -$5.2M Sold | 0.25% 55.7K shares | 112.9K → 55.7K −$5.2M | -50.65% | $2.0B Mid Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $5.0M 1.26% | -$3.8M Sold | 0.292% 307.2K shares | 539.7K → 307.2K −$3.8M | -43.09% | $1.7B Small Cap | Q2 2025 Held for 5 months | |
Medical - Instruments & Supplies Healthcare | $4.9M 1.24% | +$4.9M Bought | 0.091% 40.1K shares | — | — | $5.4B Mid Cap | Q3 2023 Held for 2y 2m | |
Medical - Healthcare Information Services Healthcare | $4.8M 1.22% | +$4.8M New | 1.59% 320.3K shares | 0 → 320.3K +$4.8M | New | $303.3M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $4.4M 1.12% | — | 1.97% 2.1M shares | — | — | $224.4M Micro Cap | Q4 2024 Held for 11 months | |
Unknown Unknown | $4.4M 1.11% | +$4.4M New | 1.72% 350.0K shares | 0 → 350.0K +$4.4M | New | $255.5M Micro Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $3.7M 0.934% | -$1.5M Sold | 4.98% 2.6M shares | 3.7M → 2.6M −$1.5M | -29.42% | $74.2M Micro Cap | Q2 2024 Held for 1y 5m | |
Unknown Unknown | $3.6M 0.901% | -$7.4M Sold | 0.424% 189.2K shares | 584.4K → 189.2K −$7.4M | -67.63% | $838.6M Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $3.4M 0.855% | — | 0.142% 124.2K shares | — | — | $2.4B Mid Cap | Q3 2022 Held for 3y 2m | |
Biotechnology Healthcare | $3.3M 0.833% | — | 4.83% 335.9K shares | — | — | $68.1M Micro Cap | Q1 2025 Held for 8 months | |
Biotechnology Healthcare | $3.0M 0.756% | — | 0.483% 1.4M shares | — | — | $618.4M Small Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $2.7M 0.691% | — | 0.344% 478.3K shares | — | — | $793.2M Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $2.6M 0.657% | — | 0.421% 726.9K shares | — | — | $617.0M Small Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $2.6M 0.653% | -$1.5M Sold | 1.16% 829.2K shares | 1.3M → 829.2K −$1.5M | -36.61% | $221.8M Micro Cap | Q1 2024 Held for 1y 8m | |
Medical - Devices Healthcare | $2.1M 0.531% | -$1.0M Sold | 4.72% 2.4M shares | 3.5M → 2.4M −$1.0M | -33.01% | $44.4M Nano Cap | Q2 2025 Held for 5 months | |
Biotechnology Healthcare | $1.9M 0.47% | -$1.0M Sold | 2.01% 1.4M shares | 2.2M → 1.4M −$1.0M | -36.04% | $92.4M Micro Cap | Q4 2024 Held for 11 months | |
Unknown Unknown | $1.5M 0.383% | +$1.5M New | 0.165% 130.6K shares | 0 → 130.6K +$1.5M | New | $917.1M Small Cap | Q3 2025 Held for 2 months | |
Biotechnology Healthcare | $1.3M 0.329% | — | 1.5% 1.3M shares | — | — | $86.9M Micro Cap | Q2 2024 Held for 1y 5m | |
Medical - Devices Healthcare | $1.0M 0.255% | -$1.1M Sold | 0.284% 2.3M shares | 4.9M → 2.3M −$1.1M | -52.28% | $355.0M Small Cap | Q2 2025 Held for 5 months | |
Medical - Devices Healthcare | $948.1K 0.24% | — | 1.61% 636.3K shares | — | — | $59.0M Micro Cap | Q4 2024 Held for 11 months | |
Biotechnology Healthcare | $917.3K 0.232% | — | 0.549% 72.2K shares | — | — | $167.2M Micro Cap | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $600.9K 0.152% | — | 0.217% 122.9K shares | — | — | $276.4M Micro Cap | Q4 2023 Held for 1y 11m | |
Medical - Devices Healthcare | $549.9K 0.139% | — | 1.42% 785.8K shares | — | — | $38.7M Nano Cap | Q2 2022 Held for 3y 5m | |
Medical - Instruments & Supplies Healthcare | $233.9K 0.059% | — | 0.135% 50.8K shares | — | — | $172.7M Micro Cap | Q4 2022 Held for 2y 11m | |
Biotechnology Healthcare | $201.3K 0.051% | — | — 163.7K shares | — | — | — — | Q1 2024 Held for 1y 8m | |
Biotechnology Healthcare | $165.5K 0.042% | -$246.5K Sold | 1.93% 112.2K shares | 279.4K → 112.2K −$246.5K | -59.83% | $8.6M Nano Cap | Q1 2023 Held for 2y 8m | |
Biotechnology Healthcare | $75.9K 0.019% | — | 0.012% 10.1K shares | — | — | $657.2M Small Cap | Q3 2024 Held for 1y 2m | |
Biotechnology Healthcare | $64.1K 0.016% | -$9.8 Sold | 0.409% 10.9K shares | 10.9K → 10.9K −$9.8 | -0.02% | $15.7M Nano Cap | Q4 2021 Held for 3y 11m | |
Biotechnology Healthcare | $14.4K 0.004% | — | — 400.0K shares | — | — | — — | Q3 2023 Held for 2y 2m |
