Neurocrine Biosciences

NBIX • NASDAQ

Neurocrine Biosciences is a drug manufacturers - specialty & generic company in the healthcare sector on NASDAQ, led by Kyle Gano, Ph.D., with a market cap of $15.2B. As of Q3 2025, 97% of shares are held by 628 institutional investors, with BlackRock, Inc. as the largest holder at 12.81%.

President and Chief Executive OfficerKyle Gano, Ph.D.

Market Cap$15.2B

Drug Manufacturers - Specialty & Generic

Healthcare

Employees1.4K

Websiteneurocrine.com

Country

United States of America

Overview

Overview of institutional ownership in NBIX as of Q3 2025 with a market cap of $13.9B

All Institutions

Institutions: 628
Value Held: $13.5B
Shares Held: 96.6M
Avg Position: $21.6M
Median Position: $1.1M

Hedge Funds

Hedge Funds: 73
Value Held: $2.2B
Shares Held: 15.6M
Avg Position: $30.0M
Median Position: $5.3M

Ownership Breakdown

Institutional (non-HF)

81.48%

$11.3B

Hedge Funds

15.75%

$2.2B

Retail & Other

2.77%

$385.0M

Based on market cap of $13.9B as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in NBIX as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
B BlackRock, Inc. Institution	-	$1.8B 0.03% of portfolio	12.81% 12.7M shares	≤ Q2 2013 Held for 12y 5m+	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$1.4B 0.02% of portfolio	9.79% 9.7M shares	≤ Q2 2013 Held for 12y 5m+	$6.69T
DODGE & COX Long Only Manager	Dana Morton Emery CEO	$780.0M 0.42% of portfolio	5.60% 5.6M shares	Q3 2023 Held for 2y 2m	$185.33B
JPMORGAN CHASE & CO Institution	Jamie Dimon CEO	$664.0M 0.04% of portfolio	4.77% 4.7M shares	Q4 2014 Held for 10y 11m	$1.56T
STATE STREET CORP Institution	Ronald P. O'Hanley CEO	$610.2M 0.02% of portfolio	4.38% 4.3M shares	≤ Q2 2013 Held for 12y 5m+	$2.88T
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	Robert W Sharps President	$402.4M 0.04% of portfolio	2.89% 2.9M shares	≤ Q2 2013 Held for 12y 5m+	$912.31B
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	David Gary Kabiller Founder	$388.4M 0.25% of portfolio	2.80% 2.8M shares	Q1 2018 Held for 7y 8m	$156.17B
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	$339.5M 0.45% of portfolio	2.44% 2.4M shares	Q4 2017 Held for 7y 11m	$75.8B
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$283.5M 0.02% of portfolio	2.04% 2.0M shares	≤ Q2 2013 Held for 12y 5m+	$1.57T
MORGAN STANLEY RIA/Wealth	Jed Finn CEO	$256.5M 0.02% of portfolio	1.84% 1.8M shares	≤ Q2 2013 Held for 12y 5m+	$1.65T

Net Capital Flow

Institutional buying and selling activity for NBIX in Q3 2025

Traded: −$126.0M
Buyers: 333
Sellers: 264
Total Bought: +$1.1B
Total Sold: −$1.2B
Avg Position: $20.0M

Biggest Buyers

Institution	Net Bought	Current Position
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$177.0M +1.3M shares	$388.4M 2.8M shares
S Swedbank AB Institution	+$75.7M +539.0K shares	$76.8M 547.3K shares
JPMORGAN CHASE & CO Institution	+$65.8M +468.4K shares	$664.0M 4.7M shares
LOS ANGELES CAPITAL MANAGEMENT & EQUITY RESEARCH INC Long Only Manager	+$64.3M +458.1K shares	$168.8M 1.2M shares
TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy	+$48.8M +347.6K shares	$48.8M 347.6K shares
ARROWSTREET CAPITAL LIMITED PARTNERSHIP Hedge Fund•Quant	+$40.2M +286.5K shares	$57.8M 411.7K shares
Hood River Capital Management LLC Long Only Manager	+$34.2M +244.0K shares	$70.4M 501.5K shares
BALYASNY ASSET MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$28.6M +203.4K shares	$28.6M 203.4K shares
PERCEPTIVE ADVISORS LLC Hedge Fund•Long/Short	+$27.4M +195.0K shares	$63.2M 450.1K shares
J JANE STREET GROUP, LLC Institution	+$27.0M +192.1K shares	$28.0M 199.2K shares

Biggest Sellers

Institution	Net Sold	Current Position
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	−$176.3M −1.3M shares	$111.4M 793.2K shares
UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager	−$87.4M −622.4K shares	$107.4M 765.2K shares
V VIRGINIA RETIREMENT SYSTEMS ET AL Institution	−$70.5M −502.4K shares	$13.8M 98.4K shares
A AXA Institution	−$43.0M −341.7K shares	Sold Off 0 shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	−$42.9M −341.6K shares	Sold Off 0 shares
B BRAIDWELL LP Hedge Fund•Multi-Strategy	−$39.3M −280.1K shares	$123.6M 880.3K shares
B BlackRock, Inc. Institution	−$34.9M −248.5K shares	$1.8B 12.7M shares
UBS Group AG Institution	−$33.3M −237.6K shares	$51.2M 364.6K shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	−$31.5M −224.6K shares	$79.6M 566.9K shares
PRICE T ROWE ASSOCIATES INC /MD/ Long Only Manager	−$30.8M −219.7K shares	$402.4M 2.9M shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited NBIX in Q3 2025

New Positions: 55
New Value: $74.7M
Exited Positions: 49
Exited Value: $236.5M

New Positions

Institution	Position Value
F First Turn Management, LLC Hedge Fund•Long/Short	$25.5M 181.9K shares
Soleus Capital Management, L.P. Hedge Fund•Long/Short	$19.4M 138.0K shares
SEIZERT CAPITAL PARTNERS, LLC Long Only Manager	$9.8M 70.0K shares
Voleon Capital Management LP Hedge Fund•Quant	$2.6M 18.3K shares
U UNIVERSITY OF TEXAS INVESTMENT MANAGMENT CO Institution	$2.1M 15.3K shares
Krilogy Financial LLC RIA/Wealth	$1.3M 8.3K shares
AZZAD ASSET MANAGEMENT INC /ADV RIA/Wealth	$1.3M 8.9K shares
Main Management ETF Advisors, LLC Institution	$1.1M 7.8K shares
J. Safra Sarasin Holding AG Fund of Funds	$878.9K 6.3K shares
O ODDO BHF ASSET MANAGEMENT SAS Institution	$788.9K 5.6K shares

Exited Positions

Institution	Previous Position
A AXA Institution	$43.0M 341.7K shares
A ADAGE CAPITAL PARTNERS GP LLC Institution	$42.9M 341.6K shares
Z Zurich Insurance Group Ltd/FI Institution	$26.6M 211.9K shares
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	$20.5M 163.0K shares
Logos Global Management LP Hedge Fund•Long/Short	$18.9M 150.0K shares
Sio Capital Management, LLC Hedge Fund•Long/Short	$12.7M 100.7K shares
Woodline Partners LP Hedge Fund•Long/Short	$8.7M 68.9K shares
S Saturn V Capital Management LLC Hedge Fund•Sector	$7.3M 58.2K shares
T TEXAS PERMANENT SCHOOL FUND Institution	$6.8M 54.0K shares
N Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. Institution	$6.8M 54.0K shares

Options Activity

Institutions with the largest Call and Put options positions in NBIX as of Q3 2025

Call Positions: 9
Call Value: $32.2M
Put Positions: 10
Put Value: $66.8M

Call Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$20.4M 1.5K contracts
Caption Management, LLC Hedge Fund•Long/Short	$4.2M 300.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$3.7M 263.0 contracts
J JANE STREET GROUP, LLC Institution	$1.9M 134.0 contracts
T Twin Tree Management, LP Hedge Fund•Vol Arbitrage	$1.1M 79.0 contracts
W WOLVERINE TRADING, LLC Institution	$883.7K 63.0 contracts
R Raiffeisen Bank International AG Institution	$56.2K 4.0 contracts
UBS Group AG Institution	- - contracts
GOLDMAN SACHS GROUP INC Institution	- - contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$24.2M 1.7K contracts
BANK OF AMERICA CORP /DE/ Institution	$14.9M 1.1K contracts
J JANE STREET GROUP, LLC Institution	$8.5M 603.0 contracts
Caption Management, LLC Hedge Fund•Long/Short	$7.4M 530.0 contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	$7.1M 507.0 contracts
T Twin Tree Management, LP Hedge Fund•Vol Arbitrage	$2.6M 187.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$1.8M 125.0 contracts
GOLDMAN SACHS GROUP INC Institution	$351.0K 25.0 contracts
J J. Goldman & Co LP Hedge Fund•Multi-Strategy	- - contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	- - contracts

Most Committed Institutions

Institutions with NBIX as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
Sarissa Capital Management LP Hedge Fund•Activist	Alexander John Denner CEO	23.59% $42.6M	0.31% 303.2K shares	Q2 2023 Held for 2y 5m	$180.4M
BOONE CAPITAL MANAGEMENT LLC Hedge Fund•Long/Short	Daniel Walter Boone President	7.66% $23.4M	0.17% 166.4K shares	Q2 2025 Held for 5 months	$305.0M
E Eagle Health Investments LP Hedge Fund•Long/Short	Gary Johnathan Stern Founder	6.00% $22.9M	0.16% 162.8K shares	Q3 2024 Held for 1y 2m	$380.9M
H HealthInvest Partners AB Institution	-	5.98% $1.5M	0.10% 102.6K shares	Q4 2023 Held for 1y 11m	$25.6M
B Bellevue Group AG Institution	-	5.15% $247.5M	1.78% 1.8M shares	Q1 2016 Held for 9y 8m	$4.8B
B BRAIDWELL LP Hedge Fund•Multi-Strategy	Brian James Kreiter CEO	5.00% $123.6M	0.89% 880.3K shares	Q1 2023 Held for 2y 8m	$2.5B
F First Turn Management, LLC Hedge Fund•Long/Short	Lisa Gable Wheatley Managing Partner	3.83% $25.5M	0.18% 181.9K shares	Q3 2025 Held for 2 months	$666.0M
DIADEMA PARTNERS LP Hedge Fund•Long/Short	Timothy Beau Bassett CIO	3.70% $5.3M	0.04% 37.8K shares	Q1 2025 Held for 8 months	$143.3M
ARMISTICE CAPITAL, LLC Hedge Fund•Long/Short	Steven Joseph Boyd Managing Partner	3.11% $97.8M	0.70% 697.0K shares	Q1 2022 Held for 3y 8m	$3.2B
B Birchview Capital, LP Hedge Fund•Value	Matthew William Strobeck CIO	3.09% $4.0M	0.03% 28.7K shares	Q3 2015 Held for 10y 2m	$130.3M

Hedge Fund Spotlight

Discover hedge funds investing in NBIX

CAPITAL FUND MANAGEMENT S.A.

Hedge Fund • Quant Macro

Portfolio ManagerJacques Charles Sauliere

Portfolio Value: $10.0B
Positions: 792
Last Reported: Q3 2025

Sector Allocation

Position in Neurocrine Biosciences

Market Value: $17.4M
Shares Held: 123.7K
Portfolio Weight: 0.17%
Owned Since: 2024-Q2

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