KalVista Pharmaceuticals

KALV • NASDAQ

KalVista Pharmaceuticals is a biotechnology company in the healthcare sector on NASDAQ, led by Benjamin L. Palleiko, with a market cap of $854.7M. As of Q3 2025, 116% of shares are held by 145 institutional investors, with VR Adviser, LLC as the largest holder at 13.32%.

Chief Executive OfficerBenjamin L. Palleiko

Market Cap$854.7M

Biotechnology

Healthcare

Employees150.0

Websitekalvista.com

Country

United States of America

Overview

Overview of institutional ownership in KALV as of Q3 2025 with a market cap of $615.4M

All Institutions

Institutions: 145
Value Held: $716.0M
Shares Held: 58.8M
Avg Position: $4.9M
Median Position: $327.9K

Hedge Funds

Hedge Funds: 30
Value Held: $217.2M
Shares Held: 17.8M
Avg Position: $7.2M
Median Position: $1.7M

Ownership Breakdown

Institutional (non-HF)

81.05%

$498.7M

Hedge Funds

35.3%

$217.2M

Retail & Other

Based on market cap of $615.4M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in KALV as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	$82.0M 4.61% of portfolio	13.32% 6.7M shares	Q4 2022 Held for 2y 11m	$1.8B
T TANG CAPITAL MANAGEMENT LLC Institution	-	$61.4M 2.42% of portfolio	9.98% 5.0M shares	Q1 2022 Held for 3y 8m	$2.5B
Frazier Life Sciences Management, L.P. Venture Capital	James Newman Topper Managing Partner	$61.4M 1.84% of portfolio	9.98% 5.0M shares	Q1 2022 Held for 3y 8m	$3.3B
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	$58.1M 1.76% of portfolio	9.44% 4.8M shares	Q1 2020 Held for 5y 8m	$3.3B
C Capital World Investors Institution	-	$38.7M 0.01% of portfolio	6.29% 3.2M shares	Q1 2024 Held for 1y 8m	$730.00B
B BlackRock, Inc. Institution	-	$38.1M 0.00% of portfolio	6.19% 3.1M shares	Q1 2017 Held for 8y 8m	$5.67T
VANGUARD GROUP INC Institution	Salim Ramji CEO	$30.5M 0.00% of portfolio	4.95% 2.5M shares	Q2 2015 Held for 10y 5m	$6.69T
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$25.5M 0.02% of portfolio	4.15% 2.1M shares	Q1 2025 Held for 8 months	$121.98B
Woodline Partners LP Hedge Fund•Long/Short	Karl Heinz Kroeker CIO	$23.4M 0.11% of portfolio	3.80% 1.9M shares	Q1 2021 Held for 4y 8m	$21.3B
GOLDMAN SACHS GROUP INC Institution	David M. Solomon CEO	$21.9M 0.00% of portfolio	3.56% 1.8M shares	Q1 2019 Held for 6y 8m	$691.34B

Net Capital Flow

Institutional buying and selling activity for KALV in Q3 2025

Traded: +$66.1M
Buyers: 81
Sellers: 59
Total Bought: +$149.9M
Total Sold: −$83.8M
Avg Position: $4.3M

Biggest Buyers

Institution	Net Bought	Current Position
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	+$21.4M +1.8M shares	$25.5M 2.1M shares
GOLDMAN SACHS GROUP INC Institution	+$20.3M +1.7M shares	$21.9M 1.8M shares
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	+$12.9M +1.1M shares	$21.1M 1.7M shares
F Freestone Grove Partners LP Hedge Fund•Multi-Strategy	+$8.6M +704.4K shares	$8.6M 704.4K shares
Sio Capital Management, LLC Hedge Fund•Long/Short	+$8.3M +683.8K shares	$8.3M 683.8K shares
K Kynam Capital Management, LP Hedge Fund•Long/Short	+$7.4M +606.2K shares	$7.4M 606.2K shares
SCHRODER INVESTMENT MANAGEMENT GROUP RIA/Wealth	+$7.4M +603.5K shares	$14.1M 1.2M shares
Bank of New York Mellon Corp Institution	+$6.0M +488.8K shares	$7.3M 596.5K shares
BARCLAYS PLC Institution	+$5.0M +409.0K shares	$7.0M 577.9K shares
MORGAN STANLEY RIA/Wealth	+$4.0M +325.2K shares	$6.9M 564.9K shares

Biggest Sellers

Institution	Net Sold	Current Position
Vestal Point Capital, LP Hedge Fund•Long/Short	−$47.8M −3.9M shares	$9.1M 750.0K shares
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	−$5.7M −468.8K shares	$16.6M 1.4M shares
StemPoint Capital LP Hedge Fund•Long/Short	−$4.0M −330.0K shares	$691.5K 56.8K shares
G GREAT POINT PARTNERS LLC Private Equity	−$3.7M −323.2K shares	Sold Off 0 shares
F First Turn Management, LLC Hedge Fund•Long/Short	−$2.4M −214.1K shares	Sold Off 0 shares
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	−$2.3M −186.3K shares	$58.1M 4.8M shares
Ikarian Capital, LLC Hedge Fund•Event Driven	−$2.2M −198.5K shares	Sold Off 0 shares
D DAFNA Capital Management LLC Hedge Fund•Event Driven	−$1.9M −159.0K shares	$5.1M 422.7K shares
R Rosalind Advisors, Inc. Institution	−$1.8M −157.7K shares	Sold Off 0 shares
DIMENSIONAL FUND ADVISORS LP Long Only Manager	−$1.6M −127.8K shares	$553.5K 45.4K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited KALV in Q3 2025

New Positions: 21
New Value: $32.0M
Exited Positions: 22
Exited Value: $15.4M

New Positions

Institution	Position Value
F Freestone Grove Partners LP Hedge Fund•Multi-Strategy	$8.6M 704.4K shares
Sio Capital Management, LLC Hedge Fund•Long/Short	$8.3M 683.8K shares
K Kynam Capital Management, LP Hedge Fund•Long/Short	$7.4M 606.2K shares
TUDOR INVESTMENT CORP ET AL Hedge Fund•Multi-Strategy	$2.2M 178.8K shares
SummitTX Capital, L.P. Hedge Fund•Multi-Strategy	$1.7M 143.6K shares
B Blue Owl Capital Holdings LP Institution	$1.5M 125.0K shares
A Artia Global Partners LP Hedge Fund•Long/Short	$506.1K 41.6K shares
Magnetar Financial LLC Hedge Fund•Multi-Strategy	$327.9K 26.9K shares
CAPSTONE INVESTMENT ADVISORS, LLC Hedge Fund•Multi-Strategy	$260.9K 21.4K shares
A AXQ CAPITAL, LP Hedge Fund•Market Neutral	$209.7K 17.2K shares

Exited Positions

Institution	Previous Position
G GREAT POINT PARTNERS LLC Private Equity	$3.7M 323.2K shares
F First Turn Management, LLC Hedge Fund•Long/Short	$2.4M 214.1K shares
Ikarian Capital, LLC Hedge Fund•Event Driven	$2.2M 198.5K shares
R Rosalind Advisors, Inc. Institution	$1.8M 157.7K shares
S Stonepine Capital Management, LLC Institution	$1.1M 100.0K shares
UBS OCONNOR LLC Long Only Manager	$898.3K 79.5K shares
S Saturn V Capital Management LLC Hedge Fund•Sector	$709.9K 62.8K shares
O OMERS ADMINISTRATION Corp Institution	$383.2K 33.9K shares
V Virtu Financial LLC Institution	$347.5K 30.7K shares
S Squarepoint Ops LLC Hedge Fund•Quant	$298.3K 26.4K shares

Options Activity

Institutions with the largest Call and Put options positions in KALV as of Q3 2025

Call Positions: 8
Call Value: $14.1M
Put Positions: 3
Put Value: $10.5M

Call Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$7.1M 5.8K contracts
Ikarian Capital, LLC Hedge Fund•Event Driven	$4.9M 4.0K contracts
BOOTHBAY FUND MANAGEMENT, LLC Fund of Funds	$1.7M 1.4K contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	$243.6K 200.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$144.9K 119.0 contracts
J JANE STREET GROUP, LLC Institution	- - contracts
BARCLAYS PLC Institution	- - contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	- - contracts

Put Positions

Institution	Position Value
Caption Management, LLC Hedge Fund•Long/Short	$10.5M 8.6K contracts
Walleye Trading Advisors, LLC Hedge Fund•Multi-Strategy	- - contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	- - contracts

Most Committed Institutions

Institutions with KALV as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
VR Adviser, LLC Venture Capital	Jessica Tong Baron CFO	4.61% $82.0M	13.32% 6.7M shares	Q4 2022 Held for 2y 11m	$1.8B
Octagon Capital Advisors LP Hedge Fund•Sector	Ting (Nmn) Jia Founder	2.43% $15.5M	2.52% 1.3M shares	Q4 2024 Held for 11 months	$637.4M
T TANG CAPITAL MANAGEMENT LLC Institution	-	2.42% $61.4M	9.98% 5.0M shares	Q1 2022 Held for 3y 8m	$2.5B
SILVERARC CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Devesh Sharad Gandhi Founder	2.41% $16.6M	2.70% 1.4M shares	Q1 2023 Held for 2y 8m	$689.7M
Parkman Healthcare Partners LLC Hedge Fund•Long/Short	Gregory Arthur Martinez CIO	2.32% $21.1M	3.43% 1.7M shares	Q1 2025 Held for 8 months	$910.1M
Sio Capital Management, LLC Hedge Fund•Long/Short	Judah Zvi Drillick CEO	2.11% $8.3M	1.35% 683.8K shares	Q3 2025 Held for 2 months	$395.2M
Frazier Life Sciences Management, L.P. Venture Capital	James Newman Topper Managing Partner	1.84% $61.4M	9.98% 5.0M shares	Q1 2022 Held for 3y 8m	$3.3B
SUVRETTA CAPITAL MANAGEMENT, LLC Hedge Fund•Long/Short	Aaron Leonard Cowen CEO	1.76% $58.1M	9.44% 4.8M shares	Q1 2020 Held for 5y 8m	$3.3B
D DAFNA Capital Management LLC Hedge Fund•Event Driven	Nathan Fischel CEO	1.29% $5.1M	0.84% 422.7K shares	Q3 2018 Held for 7y 2m	$397.7M
B Birchview Capital, LP Hedge Fund•Value	Matthew William Strobeck CIO	0.63% $816.1K	0.13% 67.0K shares	Q3 2019 Held for 6y 2m	$130.3M

Hedge Fund Spotlight

Discover hedge funds investing in KALV

Quantinno Capital Management LP

Hedge Fund • Market Neutral

Portfolio ManagerHoon Nmn Kim

Portfolio Value: $36.6B
Positions: 2,911
Last Reported: Q3 2025

Sector Allocation

Position in KalVista Pharmaceuticals

Market Value: $172.4K
Shares Held: 14.2K
Portfolio Weight: 0.00%
Owned Since: 2025-Q3

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