AC Immune
ACIU • NASDAQ
AC Immune is a biotechnology company in the healthcare sector on NASDAQ, led by Andrea Pfeifer, with a market cap of $316.9M. As of Q3 2025, 24% of shares are held by 40 institutional investors, with BVF INC/IL as the largest holder at 19.7%.
Chief Executive OfficerAndrea Pfeifer
Overview
Overview of institutional ownership in ACIU as of Q3 2025 with a market cap of $290.7M
All Institutions
- Institutions
- 40
- Value Held
- $71.2M
- Shares Held
- 24.6M
- Avg Position
- $1.8M
- Median Position
- $46.7K
Hedge Funds
- Hedge Funds
- 6
- Value Held
- $5.0M
- Shares Held
- 1.7M
- Avg Position
- $834.7K
- Median Position
- $59.3K
Ownership Breakdown
Based on market cap of $290.7M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in ACIU as of Q3 2025
| Institution | Position Value |
|---|---|
B BVF INC/IL Institution | $57.3M 2.32% of portfolio |
 WELLS FARGO & COMPANY/MN Institution | $2.9M 0.00% of portfolio |
 MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $2.6M 0.00% of portfolio |
 RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | $2.2M 0.00% of portfolio |
 ACADIAN ASSET MANAGEMENT LLC Long Only Manager | $1.2M 0.00% of portfolio |
B BlackRock, Inc. Institution | $1.2M 0.00% of portfolio |
 NORTHERN TRUST CORP Institution | $814.8K 0.00% of portfolio |
 DEUTSCHE BANK AG\ Institution | $732.3K 0.00% of portfolio |
A Assenagon Asset Management S.A. Institution | $548.8K 0.00% of portfolio |
 DIMENSIONAL FUND ADVISORS LP Long Only Manager | $513.3K 0.00% of portfolio |
Net Capital Flow
Institutional buying and selling activity for ACIU in Q3 2025
- Traded
- +$690.6K
- Buyers
- 18
- Sellers
- 18
- Total Bought
- +$2.5M
- Total Sold
- −$1.8M
- Avg Position
- $1.5M
Biggest Buyers
| Institution | Net Bought |
|---|---|
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | +$1.7M +603.0K shares |
A Assenagon Asset Management S.A. Institution | +$548.8K +189.9K shares |
 SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity | +$63.1K +21.8K shares |
 MORGAN STANLEY RIA/Wealth | +$55.3K +19.1K shares |
 Private Advisor Group, LLC RIA/Wealth | +$48.0K +16.6K shares |
 UBS Group AG Institution | +$25.9K +9.0K shares |
S SIMPLEX TRADING, LLC Institution | +$8.5K +2.9K shares |
 GOLDMAN SACHS GROUP INC Institution | +$6.5K +2.3K shares |
ACADIAN ASSET MANAGEMENT LLC Long Only Manager | +$4.5K +1.5K shares |
B BNP PARIBAS ARBITRAGE, SA Institution | +$4.3K +1.5K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | −$363.8K −125.9K shares |
NORTHERN TRUST CORP Institution | −$287.3K −99.4K shares |
 Marshall Wace LLP Institution | −$275.8K −135.8K shares |
H Handelsbanken Fonder AB Institution | −$213.1K −105.0K shares |
 Eversept Partners, LLC Hedge Fund•Long/Short | −$204.5K −100.8K shares |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | −$167.3K −57.9K shares |
DIMENSIONAL FUND ADVISORS LP Long Only Manager | −$62.5K −21.6K shares |
C CANTOR FITZGERALD, L. P. Institution | −$60.9K −30.0K shares |
WELLS FARGO & COMPANY/MN Institution | −$40.7K −14.1K shares |
 TWO SIGMA INVESTMENTS LLC Hedge Fund•Multi-Strategy | −$40.2K −13.9K shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited ACIU in Q3 2025
- New Positions
- 2
- New Value
- $50.9K
- Exited Positions
- 6
- Exited Value
- $800.5K
New Positions
| Institution | Position Value |
|---|---|
Private Advisor Group, LLC RIA/Wealth | $48.0K 16.6K shares |
 Rockefeller Capital Management L.P. Long Only Manager | $2.9K 1.0K shares |
Exited Positions
| Institution | Previous Position |
|---|---|
Marshall Wace LLP Institution | $275.8K 135.8K shares |
H Handelsbanken Fonder AB Institution | $213.1K 105.0K shares |
Eversept Partners, LLC Hedge Fund•Long/Short | $204.5K 100.8K shares |
C CANTOR FITZGERALD, L. P. Institution | $60.9K 30.0K shares |
S Squarepoint Ops LLC Hedge Fund•Quant | $25.7K 12.6K shares |
T TWO SIGMA SECURITIES, LLC Institution | $20.5K 10.1K shares |
Options Activity
Institutions with the largest Call and Put options positions in ACIU as of Q3 2025
- Call Positions
- 1
- Call Value
- $274.3K
- Put Positions
- 1
- Put Value
- $65.0K
Call Positions
| Institution | Position Value |
|---|---|
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | $274.3K 949.0 contracts |
Put Positions
| Institution | Position Value |
|---|---|
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy | $65.0K 225.0 contracts |
Most Committed Institutions
Institutions with ACIU as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
B BVF INC/IL Institution | 2.32% $57.3M |
S | 0.02% $28.9K |
C China Universal Asset Management Co., Ltd. Institution | 0.00% $50.9K |
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant | 0.00% $2.2M |
ACADIAN ASSET MANAGEMENT LLC Long Only Manager | 0.00% $1.2M |
 Quinn Opportunity Partners LLC Hedge Fund•Event Driven | 0.00% $29.2K |
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy | 0.00% $2.6M |
B Banque Cantonale Vaudoise Institution | 0.00% $53.3K |
A Assenagon Asset Management S.A. Institution | 0.00% $548.8K |
WELLS FARGO & COMPANY/MN Institution | 0.00% $2.9M |
Hedge Fund Spotlight
Discover hedge funds investing in ACIU
Quinn Opportunity Partners LLC
Hedge Fund • Event Driven
Portfolio ManagerPatrick Farley Quinn
- Portfolio Value
- $1.4B
- Positions
- 319
- Last Reported
- Q3 2025
Sector Allocation
Position in AC Immune
- Market Value
- $29.2K
- Shares Held
- 10.1K
- Portfolio Weight
- 0.00%
- Owned Since
- 2024-Q4
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Electronic Gaming & Multimedia Technology | $156.8M | 11.48% | |
Telecommunications Services Communication Services | $59.7M | 4.37% | |
Leisure Consumer Cyclical | $51.7M | 3.79% |
