Actuate Therapeutics, Inc.
ACTU • XNAS
Actuate Therapeutics, Inc. is a pharmaceutical preparations company on XNAS, led by Daniel M. Schmitt, with a market cap of $174.8M. As of Q3 2025, 52% of shares are held by 42 institutional investors, with BIOS Capital Management, LP as the largest holder at 43.24%.
President and Chief Executive OfficerDaniel M. Schmitt
Overview
Overview of institutional ownership in ACTU as of Q3 2025 with a market cap of $155.5M
All Institutions
- Institutions
- 42
- Value Held
- $80.5M
- Shares Held
- 12.0M
- Avg Position
- $1.9M
- Median Position
- $41.6K
Hedge Funds
- Hedge Funds
- 1
- Value Held
- $5.9K
- Shares Held
- 885.0
- Avg Position
- $5.9K
- Median Position
- $5.9K
Ownership Breakdown
Based on market cap of $155.5M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.
Biggest Investors
Institutions with the largest positions in ACTU as of Q3 2025
| Institution | Position Value |
|---|---|
 BIOS Capital Management, LP Venture Capital | $67.2M 75.62% of portfolio |
V Voss Capital LLC Institution | $6.0M 0.34% of portfolio |
 VANGUARD GROUP INC Institution | $2.1M 0.00% of portfolio |
B BlackRock, Inc. Institution | $1.9M 0.00% of portfolio |
 GEODE CAPITAL MANAGEMENT LLC ETF Provider | $972.8K 0.00% of portfolio |
 NORTHERN TRUST CORP Institution | $571.7K 0.00% of portfolio |
 STATE STREET CORP Institution | $333.8K 0.00% of portfolio |
N NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO Institution | $129.1K 0.00% of portfolio |
G Gleason Group, Inc. Institution | $127.3K 0.01% of portfolio |
 SFMG, LLC Fund of Funds | $113.7K 0.01% of portfolio |
Net Capital Flow
Institutional buying and selling activity for ACTU in Q3 2025
- Traded
- +$5.4M
- Buyers
- 22
- Sellers
- 14
- Total Bought
- +$6.1M
- Total Sold
- −$676.8K
- Avg Position
- $1.8M
Biggest Buyers
| Institution | Net Bought |
|---|---|
V Voss Capital LLC Institution | +$4.1M +610.1K shares |
B BlackRock, Inc. Institution | +$579.5K +86.6K shares |
BIOS Capital Management, LP Venture Capital | +$568.1K +84.9K shares |
VANGUARD GROUP INC Institution | +$344.8K +51.5K shares |
GEODE CAPITAL MANAGEMENT LLC ETF Provider | +$183.1K +27.4K shares |
STATE STREET CORP Institution | +$123.6K +18.5K shares |
R ROYAL BANK OF CANADA Institution | +$77.8K +11.6K shares |
 UBS Group AG Institution | +$44.0K +6.6K shares |
 Sontag Advisory, LLC RIA/Wealth | +$33.5K +5.0K shares |
SFMG, LLC Fund of Funds | +$16.4K +2.5K shares |
Biggest Sellers
| Institution | Net Sold |
|---|---|
 BARCLAYS PLC Institution | −$190.5K −28.5K shares |
N NORTHWESTERN UNIVERSITY Institution | −$142.4K −21.3K shares |
N NEW YORK STATE COMMON RETIREMENT FUND Institution | −$73.6K −11.0K shares |
 BANK OF AMERICA CORP /DE/ Institution | −$69.7K −10.4K shares |
 Chicago Partners Investment Group LLC RIA/Wealth | −$68.4K −10.4K shares |
 DEUTSCHE BANK AG\ Institution | −$61.4K −9.2K shares |
T TANG CAPITAL MANAGEMENT LLC Institution | −$32.0K −5.2K shares |
L LPL Financial LLC Institution | −$16.7K −2.5K shares |
 CITIGROUP INC Institution | −$12.2K −1.8K shares |
M MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Institution | −$3.4K −506.0 shares |
Entry and Exit Activity
Institutions that initiated new positions or completely exited ACTU in Q3 2025
- New Positions
- 7
- New Value
- $46.1K
- Exited Positions
- 2
- Exited Value
- $100.4K
New Positions
| Institution | Position Value |
|---|---|
Sontag Advisory, LLC RIA/Wealth | $33.5K 5.0K shares |
 Prosight Management, LP Hedge Fund•Long/Short | $5.9K 885.0 shares |
R Russell Investments Group, Ltd. RIA/Wealth | $3.3K 487.0 shares |
 PNC FINANCIAL SERVICES GROUP, INC. Institution | $2.6K 384.0 shares |
E EverSource Wealth Advisors, LLC RIA/Wealth | $469.0 70.0 shares |
 SRS Capital Advisors, Inc. RIA/Wealth | $401.0 60.0 shares |
 CWM, LLC RIA/Wealth | - 51.0 shares |
Exited Positions
| Institution | Previous Position |
|---|---|
Chicago Partners Investment Group LLC RIA/Wealth | $68.4K 10.4K shares |
T TANG CAPITAL MANAGEMENT LLC Institution | $32.0K 5.2K shares |
Options Activity
Institutions with the largest Call and Put options positions in ACTU as of Q3 2025
- Call Positions
- 0
- Call Value
- -
- Put Positions
- 0
- Put Value
- -
Call Positions
| Institution | Position Value |
|---|---|
| No call positions found | |
Put Positions
| Institution | Position Value |
|---|---|
| No put positions found | |
Most Committed Institutions
Institutions with ACTU as the highest % of their portfolio as of Q3 2025
| Institution | Portfolio Weight |
|---|---|
BIOS Capital Management, LP Venture Capital | 75.62% $67.2M |
V Voss Capital LLC Institution | 0.34% $6.0M |
N NORTHWESTERN UNIVERSITY Institution | 0.08% $43.4K |
G Gleason Group, Inc. Institution | 0.01% $127.3K |
SFMG, LLC Fund of Funds | 0.01% $113.7K |
F Freestone Capital Holdings, LLC RIA/Wealth | 0.00% $66.9K |
Prosight Management, LP Hedge Fund•Long/Short | 0.00% $5.9K |
 Global Retirement Partners, LLC RIA/Wealth | 0.00% $41.8K |
T Tower Research Capital LLC Institution | 0.00% $11.0K |
Sontag Advisory, LLC RIA/Wealth | 0.00% $33.5K |
Hedge Fund Spotlight
Discover hedge funds investing in ACTU
Prosight Management, LP
Hedge Fund • Long/Short
Portfolio ManagerWilliam Lawrence Hawkins
- Portfolio Value
- $376.7M
- Positions
- 40
- Last Reported
- Q3 2025
Sector Allocation
Position in Actuate Therapeutics, Inc.
- Market Value
- $5.9K
- Shares Held
- 885.0
- Portfolio Weight
- 0.00%
- Owned Since
- 2025-Q3
| Top Holding | Sector | Market Value | Weight |
|---|---|---|---|
Biotechnology Healthcare | $33.7M | 8.94% | |
Biotechnology Healthcare | $29.9M | 7.94% | |
Biotechnology Healthcare | $24.4M | 6.48% |
