Enanta Pharmaceuticals

ENTA • NASDAQ

Enanta Pharmaceuticals is a biotechnology company in the healthcare sector on NASDAQ, led by Jay R. Luly, with a market cap of $425.1M. As of Q3 2025, 89% of shares are held by 119 institutional investors, with FARALLON CAPITAL MANAGEMENT LLC as the largest holder at 9.93%.

President and Chief Executive OfficerJay R. Luly

Market Cap$425.1M

Biotechnology

Healthcare

Employees145.0

Websiteenanta.com

Country

United States of America

Overview

Overview of institutional ownership in ENTA as of Q3 2025 with a market cap of $255.9M

All Institutions

Institutions: 119
Value Held: $227.1M
Shares Held: 19.0M
Avg Position: $1.9M
Median Position: $215.5K

Hedge Funds

Hedge Funds: 23
Value Held: $94.3M
Shares Held: 7.9M
Avg Position: $4.1M
Median Position: $900.1K

Ownership Breakdown

Institutional (non-HF)

51.89%

$132.8M

Hedge Funds

36.86%

$94.3M

Retail & Other

11.25%

$28.8M

Based on market cap of $255.9M as of Q3 2025. Institutional (non-HF) excludes hedge funds to avoid double counting.

Biggest Investors

Institutions with the largest positions in ENTA as of Q3 2025

Institution	Key People	Position Value	Ownership	Owned Since	Total AUM (Long)
FARALLON CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	Edric Calvin Saito Managing Partner	$25.4M 0.14% of portfolio	9.93% 2.1M shares	Q3 2017 Held for 8y 2m	$17.7B
K Krensavage Asset Management, LLC Hedge Fund•Long/Short	Michael Paul Krensavage CEO	$25.3M 12.66% of portfolio	9.89% 2.1M shares	Q1 2015 Held for 10y 8m	$199.9M
HENDERSON GROUP PLC Institution	Ali Dibadj CEO	$23.3M 0.01% of portfolio	9.11% 1.9M shares	Q2 2025 Held for 5 months	$218.74B
VANGUARD GROUP INC Institution	Salim Ramji CEO	$23.2M 0.00% of portfolio	9.07% 1.9M shares	≤ Q2 2013 Held for 12y 5m+	$6.69T
B BlackRock, Inc. Institution	-	$21.9M 0.00% of portfolio	8.57% 1.8M shares	Q2 2014 Held for 11y 5m	$5.67T
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	Dan Michael Berkovitz Chairman	$11.3M 0.01% of portfolio	4.43% 948.1K shares	Q2 2016 Held for 9y 5m	$121.98B
ACADIAN ASSET MANAGEMENT LLC Long Only Manager	Gillian Morna Therese Savage CEO	$10.4M 0.02% of portfolio	4.06% 867.0K shares	Q2 2023 Held for 2y 5m	$51.5B
COMMODORE CAPITAL LP Hedge Fund•Long/Short	Michael Jonathan Kramarz Managing Partner	$9.6M 0.47% of portfolio	3.74% 800.0K shares	Q3 2025 Held for 2 months	$2.0B
GEODE CAPITAL MANAGEMENT LLC ETF Provider	David Kenneth Lane CEO	$5.9M 0.00% of portfolio	2.31% 493.2K shares	≤ Q2 2013 Held for 12y 5m+	$1.57T
RENAISSANCE TECHNOLOGIES LLC Hedge Fund•Quant	Peter Fitzhugh Brown CEO	$5.7M 0.01% of portfolio	2.24% 479.6K shares	Q1 2016 Held for 9y 8m	$75.8B

Net Capital Flow

Institutional buying and selling activity for ENTA in Q3 2025

Traded: +$8.9M
Buyers: 57
Sellers: 52
Total Bought: +$39.1M
Total Sold: −$30.2M
Avg Position: $1.7M

Biggest Buyers

Institution	Net Bought	Current Position
HENDERSON GROUP PLC Institution	+$17.0M +1.4M shares	$23.3M 1.9M shares
COMMODORE CAPITAL LP Hedge Fund•Long/Short	+$9.6M +800.0K shares	$9.6M 800.0K shares
Point72 Asset Management, L.P. Hedge Fund•Multi-Strategy	+$3.6M +300.0K shares	$3.6M 300.0K shares
N Nuveen, LLC Institution	+$1.4M +119.9K shares	$2.0M 164.8K shares
StemPoint Capital LP Hedge Fund•Long/Short	+$900.1K +75.2K shares	$900.1K 75.2K shares
Connor, Clark & Lunn Investment Management Ltd. Long Only Manager	+$750.6K +62.7K shares	$927.7K 77.5K shares
GOLDMAN SACHS GROUP INC Institution	+$602.1K +50.3K shares	$2.0M 166.4K shares
C Cubist Systematic Strategies, LLC Institution	+$598.3K +50.0K shares	$598.3K 50.0K shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	+$521.2K +43.5K shares	$1.4M 117.3K shares
M Man Group plc Institution	+$480.7K +40.2K shares	$480.7K 40.2K shares

Biggest Sellers

Institution	Net Sold	Current Position
Marshall Wace LLP Institution	−$7.0M −582.0K shares	$3.3M 275.4K shares
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$6.1M −510.5K shares	$11.3M 948.1K shares
S Stonepine Capital Management, LLC Institution	−$3.6M −299.1K shares	$3.7M 305.0K shares
AQR CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	−$2.0M −169.3K shares	$2.7M 226.8K shares
Trexquant Investment LP Hedge Fund•Quant	−$1.6M −137.6K shares	$1.5M 127.4K shares
Sio Capital Management, LLC Hedge Fund•Long/Short	−$1.4M −178.8K shares	Sold Off 0 shares
UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager	−$1.1M −149.2K shares	Sold Off 0 shares
Q Qube Research & Technologies Ltd Institution	−$861.7K −72.0K shares	$142.7K 11.9K shares
D D. E. Shaw & Co., Inc. Institution	−$676.7K −56.5K shares	$2.7M 225.7K shares
NORTHERN TRUST CORP Institution	−$662.2K −55.3K shares	$2.3M 195.9K shares

Entry and Exit Activity

Institutions that initiated new positions or completely exited ENTA in Q3 2025

New Positions: 8
New Value: $1.6M
Exited Positions: 10
Exited Value: $3.4M

New Positions

Institution	Position Value
StemPoint Capital LP Hedge Fund•Long/Short	$900.1K 75.2K shares
P PharVision Advisers, LLC Hedge Fund•Long/Short	$429.1K 35.8K shares
Harvest Investment Services, LLC RIA/Wealth	$146.0K 12.2K shares
Q Quarry LP Institution	$80.8K 6.8K shares
O Optiver Holding B.V. Institution	$3.1K 258.0 shares
Johnson Financial Group, Inc. RIA/Wealth	$2.3K 188.0 shares
J JONES FINANCIAL COMPANIES LLLP Institution	$474.0 60.0 shares
S SBI Securities Co., Ltd. Institution	$12.0 1.0 shares

Exited Positions

Institution	Previous Position
Sio Capital Management, LLC Hedge Fund•Long/Short	$1.4M 178.8K shares
UBS GLOBAL ASSET MANAGEMENT AMERICAS INC Long Only Manager	$1.1M 149.2K shares
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$447.1K 59.1K shares
V Virtu Financial LLC Institution	$238.4K 31.5K shares
S SHERBROOKE PARK ADVISERS LLC Hedge Fund•Quant	$94.8K 12.5K shares
INTECH INVESTMENT MANAGEMENT LLC Long Only Manager	$83.9K 11.1K shares
$US BANCORP \DE\ logo$ US BANCORP \DE\ Institution	$44.7K 5.9K shares
Caitong International Asset Management Co., Ltd RIA/Wealth	$1.5K 195.0 shares
FIFTH THIRD BANCORP Institution	$839.0 111.0 shares
RAYMOND JAMES FINANCIAL INC RIA/Wealth	$378.0 50.0 shares

Options Activity

Institutions with the largest Call and Put options positions in ENTA as of Q3 2025

Call Positions: 4
Call Value: $3.5M
Put Positions: 3
Put Value: $738.5K

Call Positions

Institution	Position Value
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	$2.3M 1.9K contracts
J JANE STREET GROUP, LLC Institution	$537.5K 449.0 contracts
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$337.6K 282.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$318.4K 266.0 contracts

Put Positions

Institution	Position Value
SUSQUEHANNA INTERNATIONAL GROUP, LLP Private Equity	$396.2K 331.0 contracts
MILLENNIUM MANAGEMENT LLC Hedge Fund•Multi-Strategy	$198.7K 166.0 contracts
CITADEL ADVISORS LLC Hedge Fund•Multi-Strategy	$143.6K 120.0 contracts

Most Committed Institutions

Institutions with ENTA as the highest % of their portfolio as of Q3 2025

Institution	Key People	Portfolio Weight	Ownership	Owned Since	Total AUM (Long)
K Krensavage Asset Management, LLC Hedge Fund•Long/Short	Michael Paul Krensavage CEO	12.66% $25.3M	9.89% 2.1M shares	Q1 2015 Held for 10y 8m	$199.9M
S Stonepine Capital Management, LLC Institution	-	2.97% $3.7M	1.43% 305.0K shares	Q4 2024 Held for 11 months	$123.0M
COMMODORE CAPITAL LP Hedge Fund•Long/Short	Michael Jonathan Kramarz Managing Partner	0.47% $9.6M	3.74% 800.0K shares	Q3 2025 Held for 2 months	$2.0B
P PharVision Advisers, LLC Hedge Fund•Long/Short	Blagovest Dimitrov Baychev CEO	0.24% $429.1K	0.17% 35.8K shares	Q3 2025 Held for 2 months	$176.9M
StemPoint Capital LP Hedge Fund•Long/Short	Sean Chua Tan President	0.18% $900.1K	0.35% 75.2K shares	Q3 2025 Held for 2 months	$495.9M
FARALLON CAPITAL MANAGEMENT LLC Hedge Fund•Multi-Strategy	Edric Calvin Saito Managing Partner	0.14% $25.4M	9.93% 2.1M shares	Q3 2017 Held for 8y 2m	$17.7B
PDT Partners, LLC Hedge Fund•Quant	Peter (Nmn) Muller CEO	0.07% $1.0M	0.40% 86.0K shares	Q2 2023 Held for 2y 5m	$1.6B
T TANG CAPITAL MANAGEMENT LLC Institution	-	0.06% $1.5M	0.59% 126.7K shares	Q4 2023 Held for 1y 11m	$2.5B
S Skopos Labs, Inc. RIA/Wealth	Erkko Mikonpoika Etula CEO	0.03% $323.6K	0.20% 43.2K shares	Q2 2025 Held for 5 months	$926.8M
Portland Global Advisors LLC RIA/Wealth	John Barker Sullivan CEO	0.03% $290.6K	0.11% 24.3K shares	Q3 2021 Held for 4y 2m	$895.6M

Hedge Fund Spotlight

Discover hedge funds investing in ENTA

Campbell & CO Investment Adviser LLC

Hedge Fund • Quant Macro

Portfolio ManagerKevin Dwayne Cole

Portfolio Value: $1.3B
Positions: 1,051
Last Reported: Q3 2025

Sector Allocation

Position in Enanta Pharmaceuticals

Market Value: $225.7K
Shares Held: 18.9K
Portfolio Weight: 0.02%
Owned Since: 2025-Q3

Top Holding	Sector	Market Value	Weight
1 Wheaton Precious Metals WPM	Gold Basic Materials	$11.4M	0.86%
2 RIO Rio Tinto RIO	Unknown Unknown	$9.5M	0.72%
3 Sprouts Farmers Market SFM	Grocery Stores Consumer Defensive	$9.3M	0.71%

View full profile

Enanta Pharmaceuticals

Overview

All Institutions

Hedge Funds

Ownership Breakdown

Biggest Investors

Net Capital Flow

Biggest Buyers

Biggest Sellers

Entry and Exit Activity

New Positions

Exited Positions

Options Activity

Call Positions

Put Positions

Most Committed Institutions

Hedge Fund Spotlight

Position in Enanta Pharmaceuticals

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